FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147447690> ?p ?o ?g. }

• W2147447690 endingPage "2603" @default.
• W2147447690 startingPage "2595" @default.
• W2147447690 abstract "Extensive studies of the well-known legume and rhizobium symbiosis model system suggest that the purine metabolic pathway plays a key role in microbe–plant interactions, although the exact mechanism is unknown. Here, we report the impact of a key purine metabolic gene, purL , on the symbiotic interaction between the bacterium Photorhabdus temperata and its nematode partner Heterorhabditis bacteriophora . Real-time PCR assays showed that the purL gene was upregulated in P. temperata in the nematode infective juvenile compared with artificial media. Mutation of the purL gene by in-frame deletion dramatically decreased the capacity of the bacterium to persist in infective juveniles and its ability to form biofilm in vitro . It was further demonstrated that purL gene expression was positively related to bacterial biofilm formation and the symbiotic persistence of the bacterium in nematode infective juveniles. A Δ purL mutant lost the ability to support infective juvenile formation in the media which weakly supported biofilm formation, suggesting that a critical level of biofilm formation is required by the bacteria to support infective juvenile formation and thus establish their partnership. In addition, the defects in both biofilm formation and symbiotic ability due to the disruption of the purL gene could be partially restored by the addition of 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR), an intermediate of the purine biosynthesis pathway. Overall, these data indicate that the purine metabolic pathway is important in microbe–animal symbioses, and that it may influence symbiotic interactions at the level of biofilm formation." @default.
• W2147447690 created "2016-06-24" @default.
• W2147447690 creator A5019269636 @default.
• W2147447690 creator A5057365183 @default.
• W2147447690 date "2011-09-01" @default.
• W2147447690 modified "2023-10-17" @default.
• W2147447690 title "purL gene expression affects biofilm formation and symbiotic persistence of Photorhabdus temperata in the nematode Heterorhabditis bacteriophora" @default.
• W2147447690 cites W1493879424 @default.
• W2147447690 cites W1538322069 @default.
• W2147447690 cites W1592582327 @default.
• W2147447690 cites W1847545745 @default.
• W2147447690 cites W1984063404 @default.
• W2147447690 cites W1985782125 @default.
• W2147447690 cites W1994799842 @default.
• W2147447690 cites W2016158447 @default.
• W2147447690 cites W2017232450 @default.
• W2147447690 cites W2021273689 @default.
• W2147447690 cites W2037442681 @default.
• W2147447690 cites W2060081344 @default.
• W2147447690 cites W2066210978 @default.
• W2147447690 cites W2070590323 @default.
• W2147447690 cites W2070729321 @default.
• W2147447690 cites W2074228260 @default.
• W2147447690 cites W2075194456 @default.
• W2147447690 cites W2077586102 @default.
• W2147447690 cites W2078767021 @default.
• W2147447690 cites W2091621218 @default.
• W2147447690 cites W2107277218 @default.
• W2147447690 cites W2124057262 @default.
• W2147447690 cites W2124416833 @default.
• W2147447690 cites W2129016044 @default.
• W2147447690 cites W2139048483 @default.
• W2147447690 cites W2153414926 @default.
• W2147447690 cites W2159652684 @default.
• W2147447690 cites W2164028009 @default.
• W2147447690 cites W2169255384 @default.
• W2147447690 cites W2171498110 @default.
• W2147447690 cites W2171776117 @default.
• W2147447690 cites W2782373744 @default.
• W2147447690 cites W4238069606 @default.
• W2147447690 cites W4254394441 @default.
• W2147447690 cites W840998445 @default.
• W2147447690 doi "https://doi.org/10.1099/mic.0.048959-0" @default.
• W2147447690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21700665" @default.
• W2147447690 hasPublicationYear "2011" @default.
• W2147447690 type Work @default.
• W2147447690 sameAs 2147447690 @default.
• W2147447690 citedByCount "17" @default.
• W2147447690 countsByYear W21474476902012 @default.
• W2147447690 countsByYear W21474476902013 @default.
• W2147447690 countsByYear W21474476902016 @default.
• W2147447690 countsByYear W21474476902018 @default.
• W2147447690 countsByYear W21474476902019 @default.
• W2147447690 countsByYear W21474476902020 @default.
• W2147447690 countsByYear W21474476902022 @default.
• W2147447690 countsByYear W21474476902023 @default.
• W2147447690 crossrefType "journal-article" @default.
• W2147447690 hasAuthorship W2147447690A5019269636 @default.
• W2147447690 hasAuthorship W2147447690A5057365183 @default.
• W2147447690 hasBestOaLocation W21474476901 @default.
• W2147447690 hasConcept C108319773 @default.
• W2147447690 hasConcept C18903297 @default.
• W2147447690 hasConcept C2776074613 @default.
• W2147447690 hasConcept C2776213388 @default.
• W2147447690 hasConcept C2778172128 @default.
• W2147447690 hasConcept C2778758119 @default.
• W2147447690 hasConcept C2778830712 @default.
• W2147447690 hasConcept C2780004239 @default.
• W2147447690 hasConcept C43144210 @default.
• W2147447690 hasConcept C51785407 @default.
• W2147447690 hasConcept C523546767 @default.
• W2147447690 hasConcept C54355233 @default.
• W2147447690 hasConcept C55493867 @default.
• W2147447690 hasConcept C58123911 @default.
• W2147447690 hasConcept C86803240 @default.
• W2147447690 hasConcept C89423630 @default.
• W2147447690 hasConceptScore W2147447690C108319773 @default.
• W2147447690 hasConceptScore W2147447690C18903297 @default.
• W2147447690 hasConceptScore W2147447690C2776074613 @default.
• W2147447690 hasConceptScore W2147447690C2776213388 @default.
• W2147447690 hasConceptScore W2147447690C2778172128 @default.
• W2147447690 hasConceptScore W2147447690C2778758119 @default.
• W2147447690 hasConceptScore W2147447690C2778830712 @default.
• W2147447690 hasConceptScore W2147447690C2780004239 @default.
• W2147447690 hasConceptScore W2147447690C43144210 @default.
• W2147447690 hasConceptScore W2147447690C51785407 @default.
• W2147447690 hasConceptScore W2147447690C523546767 @default.
• W2147447690 hasConceptScore W2147447690C54355233 @default.
• W2147447690 hasConceptScore W2147447690C55493867 @default.
• W2147447690 hasConceptScore W2147447690C58123911 @default.
• W2147447690 hasConceptScore W2147447690C86803240 @default.
• W2147447690 hasConceptScore W2147447690C89423630 @default.
• W2147447690 hasIssue "9" @default.
• W2147447690 hasLocation W21474476901 @default.
• W2147447690 hasLocation W21474476902 @default.
• W2147447690 hasOpenAccess W2147447690 @default.
• W2147447690 hasPrimaryLocation W21474476901 @default.
• W2147447690 hasRelatedWork W1498410084 @default.

• next