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• W2147492435 endingPage "9342" @default.
• W2147492435 startingPage "9342" @default.
• W2147492435 abstract "The molecular in-plane and out-of-plane structure of dimyristoylphosphatidylcholine (DMPC) membranes containing up to 60 mol% of cholesterol was studied using X-ray diffraction. Up to 37.5 mol% cholesterol could be dissolved in the membranes, resulting in a disordered lateral membrane structure. Highly ordered cholesterol structures were observed at cholesterol concentrations of more than 40 mol% cholesterol. These structures were characterized as immiscible cholesterol plaques, i.e., bilayers of cholesterol molecules coexisting with the lipid bilayer. The cholesterol molecules were found to form a monoclinic structure at 40 mol% cholesterol, which transformed into a triclinic arrangement at the highest concentration of 60 mol%. Monoclinic and triclinic structures were found to coexist at cholesterol concentrations between 50 and 55 mol%." @default.
• W2147492435 created "2016-06-24" @default.
• W2147492435 creator A5006256457 @default.
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• W2147492435 date "2013-01-01" @default.
• W2147492435 modified "2023-10-10" @default.
• W2147492435 title "Solubility of cholesterol in lipid membranes and the formation of immiscible cholesterol plaques at high cholesterol concentrations" @default.
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• W2147492435 doi "https://doi.org/10.1039/c3sm50700a" @default.
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