FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147711212> ?p ?o ?g. }

• W2147711212 abstract "Micropapillary differentiation in adenocarcinomas has recently been associated with poor prognosis because these tumors are more likely to metastasize. However, no clear explanation exists as to why the presence of a micropapillary pattern is associated with metastasis. A case of primary lung adenocarcinoma with a prominent micropapillary pattern is presented here, with special reference to the immunohistochemical expression of the E-cadherin-mediated system and IQGAP1. Histologically, the tumor was diagnosed as a moderately differentiated papillary adenocarcinoma, showing an extensive micropapillary pattern, with intrapulmonary metastases, pulmonary disseminations, lymphovascular invasions, and lymph node metastases. Immunohistochemically, positive staining for the adhesion molecules E-cadherin, alpha-catenin, and beta-catenin was detected in both the micropapillary and non-micropapillary areas, whereas IQGAP1 was detected in the micropapillary, but not in the non-micropapillary, area. The adhesive function of E-cadherin depends on the integrity of the entire cadherin-catenin-actin network, and thus the expression of IQGAP1 may lead to adherens junction disassembly, and consequently, the release of carcinoma cells organizing in a micropapillary pattern. This is the first report to suggest correlation between adenocarcinoma with a micropapillary pattern and the presence of adhesion molecules, and offers an intriguing first glimpse on the role of the micropapillary pattern in the process of metastasis." @default.
• W2147711212 created "2016-06-24" @default.
• W2147711212 creator A5021016213 @default.
• W2147711212 creator A5021359572 @default.
• W2147711212 creator A5041964655 @default.
• W2147711212 creator A5044572958 @default.
• W2147711212 creator A5062214131 @default.
• W2147711212 creator A5072457551 @default.
• W2147711212 creator A5072680416 @default.
• W2147711212 creator A5083195953 @default.
• W2147711212 date "2005-07-01" @default.
• W2147711212 modified "2023-09-26" @default.
• W2147711212 title "Possible mechanism of metastasis in lung adenocarcinomas with a micropapillary pattern" @default.
• W2147711212 cites W1526118656 @default.
• W2147711212 cites W1969337484 @default.
• W2147711212 cites W1979053361 @default.
• W2147711212 cites W1986942381 @default.
• W2147711212 cites W2019602368 @default.
• W2147711212 cites W2028134580 @default.
• W2147711212 cites W2058003216 @default.
• W2147711212 cites W2066367871 @default.
• W2147711212 cites W2066629426 @default.
• W2147711212 cites W2076337034 @default.
• W2147711212 cites W2081046050 @default.
• W2147711212 cites W2084457841 @default.
• W2147711212 cites W2085761963 @default.
• W2147711212 cites W2314681666 @default.
• W2147711212 cites W2323499669 @default.
• W2147711212 cites W2414205908 @default.
• W2147711212 cites W4232704618 @default.
• W2147711212 doi "https://doi.org/10.1111/j.1440-1827.2005.01847.x" @default.
• W2147711212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15982217" @default.
• W2147711212 hasPublicationYear "2005" @default.
• W2147711212 type Work @default.
• W2147711212 sameAs 2147711212 @default.
• W2147711212 citedByCount "39" @default.
• W2147711212 countsByYear W21477112122012 @default.
• W2147711212 countsByYear W21477112122013 @default.
• W2147711212 countsByYear W21477112122014 @default.
• W2147711212 countsByYear W21477112122015 @default.
• W2147711212 countsByYear W21477112122016 @default.
• W2147711212 countsByYear W21477112122018 @default.
• W2147711212 countsByYear W21477112122019 @default.
• W2147711212 countsByYear W21477112122020 @default.
• W2147711212 countsByYear W21477112122021 @default.
• W2147711212 crossrefType "journal-article" @default.
• W2147711212 hasAuthorship W2147711212A5021016213 @default.
• W2147711212 hasAuthorship W2147711212A5021359572 @default.
• W2147711212 hasAuthorship W2147711212A5041964655 @default.
• W2147711212 hasAuthorship W2147711212A5044572958 @default.
• W2147711212 hasAuthorship W2147711212A5062214131 @default.
• W2147711212 hasAuthorship W2147711212A5072457551 @default.
• W2147711212 hasAuthorship W2147711212A5072680416 @default.
• W2147711212 hasAuthorship W2147711212A5083195953 @default.
• W2147711212 hasConcept C121608353 @default.
• W2147711212 hasConcept C126322002 @default.
• W2147711212 hasConcept C142724271 @default.
• W2147711212 hasConcept C1491633281 @default.
• W2147711212 hasConcept C149402561 @default.
• W2147711212 hasConcept C16224149 @default.
• W2147711212 hasConcept C201508349 @default.
• W2147711212 hasConcept C203014093 @default.
• W2147711212 hasConcept C204232928 @default.
• W2147711212 hasConcept C2777714996 @default.
• W2147711212 hasConcept C2778740770 @default.
• W2147711212 hasConcept C2779013556 @default.
• W2147711212 hasConcept C2780849966 @default.
• W2147711212 hasConcept C2781182431 @default.
• W2147711212 hasConcept C54355233 @default.
• W2147711212 hasConcept C71924100 @default.
• W2147711212 hasConcept C86803240 @default.
• W2147711212 hasConceptScore W2147711212C121608353 @default.
• W2147711212 hasConceptScore W2147711212C126322002 @default.
• W2147711212 hasConceptScore W2147711212C142724271 @default.
• W2147711212 hasConceptScore W2147711212C1491633281 @default.
• W2147711212 hasConceptScore W2147711212C149402561 @default.
• W2147711212 hasConceptScore W2147711212C16224149 @default.
• W2147711212 hasConceptScore W2147711212C201508349 @default.
• W2147711212 hasConceptScore W2147711212C203014093 @default.
• W2147711212 hasConceptScore W2147711212C204232928 @default.
• W2147711212 hasConceptScore W2147711212C2777714996 @default.
• W2147711212 hasConceptScore W2147711212C2778740770 @default.
• W2147711212 hasConceptScore W2147711212C2779013556 @default.
• W2147711212 hasConceptScore W2147711212C2780849966 @default.
• W2147711212 hasConceptScore W2147711212C2781182431 @default.
• W2147711212 hasConceptScore W2147711212C54355233 @default.
• W2147711212 hasConceptScore W2147711212C71924100 @default.
• W2147711212 hasConceptScore W2147711212C86803240 @default.
• W2147711212 hasLocation W21477112121 @default.
• W2147711212 hasLocation W21477112122 @default.
• W2147711212 hasOpenAccess W2147711212 @default.
• W2147711212 hasPrimaryLocation W21477112121 @default.
• W2147711212 hasRelatedWork W141125555 @default.
• W2147711212 hasRelatedWork W2046629102 @default.
• W2147711212 hasRelatedWork W2060123991 @default.
• W2147711212 hasRelatedWork W2072140828 @default.
• W2147711212 hasRelatedWork W2076775935 @default.
• W2147711212 hasRelatedWork W2123863025 @default.
• W2147711212 hasRelatedWork W2133847945 @default.
• W2147711212 hasRelatedWork W2147711212 @default.

• next