Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147911575> ?p ?o ?g. }
- W2147911575 endingPage "356" @default.
- W2147911575 startingPage "346" @default.
- W2147911575 abstract "The current World Health Organization classification considers myelodysplastic syndrome with isolated del(5q) a distinct entity owing to its characteristic clinical and pathologic features. Recently, several studies have examined survival, leukemic transformation, and various prognostic factors in these patients. However, there is a lack of detailed comparative pathologic analysis of myelodysplastic syndrome cases in which del(5q) is present in association with additional cytogenetic abnormalities. We studied 26 cases of myelodysplastic syndrome at initial diagnosis with 5q − alone, 5q − plus 1 additional abnormality, and 5q − as part of a complex karyotype. Four of 17 patients had evidence of JAK2 V617F mutation. In contrast to cases of myelodysplastic syndrome with isolated 5q−, patients with additional abnormalities had normal mean corpuscular volume and decreased platelet counts (P < .001). Based on bone marrow examination, they were significantly more likely to have increased cellularity, trilineage dysplasia, lower proportion of small hypolobated megakaryocytes, higher number of blasts, and fibrosis. The presence of these morphologic features can be used to distinguish these more aggressive cases from those with myelodysplastic syndrome with isolated 5q − and a more benign clinical course." @default.
- W2147911575 created "2016-06-24" @default.
- W2147911575 creator A5011066626 @default.
- W2147911575 creator A5014684708 @default.
- W2147911575 creator A5014710016 @default.
- W2147911575 creator A5035164689 @default.
- W2147911575 creator A5037453366 @default.
- W2147911575 creator A5043668902 @default.
- W2147911575 creator A5062344658 @default.
- W2147911575 creator A5079620168 @default.
- W2147911575 creator A5087160650 @default.
- W2147911575 date "2013-03-01" @default.
- W2147911575 modified "2023-10-16" @default.
- W2147911575 title "Bone marrow morphology predicts additional chromosomal abnormalities in patients with myelodysplastic syndrome with del(5q)" @default.
- W2147911575 cites W130856763 @default.
- W2147911575 cites W140365778 @default.
- W2147911575 cites W1528707239 @default.
- W2147911575 cites W1590689384 @default.
- W2147911575 cites W1605230984 @default.
- W2147911575 cites W161996477 @default.
- W2147911575 cites W1971885624 @default.
- W2147911575 cites W1975470759 @default.
- W2147911575 cites W1975692202 @default.
- W2147911575 cites W1978255488 @default.
- W2147911575 cites W1980344036 @default.
- W2147911575 cites W1981965189 @default.
- W2147911575 cites W1983262037 @default.
- W2147911575 cites W1986987869 @default.
- W2147911575 cites W1993884835 @default.
- W2147911575 cites W1999608888 @default.
- W2147911575 cites W2001457852 @default.
- W2147911575 cites W2001477292 @default.
- W2147911575 cites W2019828567 @default.
- W2147911575 cites W2028642168 @default.
- W2147911575 cites W2033556677 @default.
- W2147911575 cites W2034863154 @default.
- W2147911575 cites W2040462473 @default.
- W2147911575 cites W2052032788 @default.
- W2147911575 cites W2052176049 @default.
- W2147911575 cites W2052833236 @default.
- W2147911575 cites W2093845572 @default.
- W2147911575 cites W2094676835 @default.
- W2147911575 cites W2095486213 @default.
- W2147911575 cites W2100840054 @default.
- W2147911575 cites W2102895132 @default.
- W2147911575 cites W2113530911 @default.
- W2147911575 cites W2113944247 @default.
- W2147911575 cites W2114492363 @default.
- W2147911575 cites W2121533623 @default.
- W2147911575 cites W2123772708 @default.
- W2147911575 cites W2131128792 @default.
- W2147911575 cites W2133838758 @default.
- W2147911575 cites W2168052772 @default.
- W2147911575 cites W2208491121 @default.
- W2147911575 cites W2339359539 @default.
- W2147911575 cites W2424847179 @default.
- W2147911575 cites W629021208 @default.
- W2147911575 cites W2256013189 @default.
- W2147911575 cites W3044574244 @default.
- W2147911575 doi "https://doi.org/10.1016/j.humpath.2012.05.022" @default.
- W2147911575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22995330" @default.
- W2147911575 hasPublicationYear "2013" @default.
- W2147911575 type Work @default.
- W2147911575 sameAs 2147911575 @default.
- W2147911575 citedByCount "14" @default.
- W2147911575 countsByYear W21479115752014 @default.
- W2147911575 countsByYear W21479115752015 @default.
- W2147911575 countsByYear W21479115752016 @default.
- W2147911575 countsByYear W21479115752017 @default.
- W2147911575 countsByYear W21479115752018 @default.
- W2147911575 countsByYear W21479115752020 @default.
- W2147911575 countsByYear W21479115752023 @default.
- W2147911575 crossrefType "journal-article" @default.
- W2147911575 hasAuthorship W2147911575A5011066626 @default.
- W2147911575 hasAuthorship W2147911575A5014684708 @default.
- W2147911575 hasAuthorship W2147911575A5014710016 @default.
- W2147911575 hasAuthorship W2147911575A5035164689 @default.
- W2147911575 hasAuthorship W2147911575A5037453366 @default.
- W2147911575 hasAuthorship W2147911575A5043668902 @default.
- W2147911575 hasAuthorship W2147911575A5062344658 @default.
- W2147911575 hasAuthorship W2147911575A5079620168 @default.
- W2147911575 hasAuthorship W2147911575A5087160650 @default.
- W2147911575 hasConcept C104317684 @default.
- W2147911575 hasConcept C118552586 @default.
- W2147911575 hasConcept C126322002 @default.
- W2147911575 hasConcept C142724271 @default.
- W2147911575 hasConcept C174475383 @default.
- W2147911575 hasConcept C2775894508 @default.
- W2147911575 hasConcept C2780007613 @default.
- W2147911575 hasConcept C2780817109 @default.
- W2147911575 hasConcept C30481170 @default.
- W2147911575 hasConcept C50965678 @default.
- W2147911575 hasConcept C53226629 @default.
- W2147911575 hasConcept C54355233 @default.
- W2147911575 hasConcept C71924100 @default.
- W2147911575 hasConcept C86803240 @default.
- W2147911575 hasConceptScore W2147911575C104317684 @default.
- W2147911575 hasConceptScore W2147911575C118552586 @default.