FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2147919015> ?p ?o ?g. }

• W2147919015 endingPage "670" @default.
• W2147919015 startingPage "665" @default.
• W2147919015 abstract "ABSTRACT Three serial isolates of Candida albicans were obtained by direct swab or by oral saline rinses from each of five human immunodeficiency virus-infected patients with recurrent oropharyngeal candidiasis. Genotyping techniques confirmed the presence of a persistent strain in multiple episodes from the same patient, which was different from the strains isolated from other patients. Fluconazole susceptibility was determined by both an agar dilution method and the National Committee for Clinical Laboratory Standards macrobroth procedure. In four of these patients the strains developed fluconazole resistance, and in one patient the strain remained susceptible. The different isolates were propagated as yeast cells on a synthetic medium, and their cell wall proteinaceous components were extracted by treatment with β-mercaptoethanol. Protein and mannoprotein components present in the extracts were analyzed by electrophoresis, immunoblotting, and lectin-blotting techniques. The analysis showed a similar composition, with only minor qualitative and quantitative differences in the polypeptidic and antigenic patterns associated with the cell wall extracts from serial isolates from the same patient, as well as those from different strains isolated from different patients. Use of monospecific antibodies generated against two immunodominant antigens during candidiasis (enolase and the 58-kDa fibrinogen-binding mannoprotein) demonstrated their expression in all isolates tested. Overall, the antigenic makeup of C. albicans strains remained constant during the course of infection and was not affected by development of fluconazole resistance. In contrast to previous reports, the low degree of antigenic variability observed in this study may be due to the fact that the isolates were obtained from a highly homogeneous population of patients and to the uniformity in techniques used for the isolation, storage, and culture of the different strains, as well as extraction methodologies." @default.
• W2147919015 created "2016-06-24" @default.
• W2147919015 creator A5021310794 @default.
• W2147919015 creator A5022852723 @default.
• W2147919015 creator A5045811531 @default.
• W2147919015 creator A5079234292 @default.
• W2147919015 creator A5052271884 @default.
• W2147919015 date "1999-09-01" @default.
• W2147919015 modified "2023-10-18" @default.
• W2147919015 title "Low Levels of Antigenic Variability in Fluconazole-Susceptible and -Resistant Candida albicans Isolates from Human Immunodeficiency Virus-Infected Patients with Oropharyngeal Candidiasis" @default.
• W2147919015 cites W143123087 @default.
• W2147919015 cites W1760120130 @default.
• W2147919015 cites W1805917040 @default.
• W2147919015 cites W1817842078 @default.
• W2147919015 cites W1832945357 @default.
• W2147919015 cites W1872260506 @default.
• W2147919015 cites W1902891146 @default.
• W2147919015 cites W1916931565 @default.
• W2147919015 cites W1930370363 @default.
• W2147919015 cites W1945490231 @default.
• W2147919015 cites W1951872079 @default.
• W2147919015 cites W1968834637 @default.
• W2147919015 cites W1973413265 @default.
• W2147919015 cites W1973697574 @default.
• W2147919015 cites W1983377701 @default.
• W2147919015 cites W1983614856 @default.
• W2147919015 cites W1997790108 @default.
• W2147919015 cites W2006640197 @default.
• W2147919015 cites W2015027883 @default.
• W2147919015 cites W2038048862 @default.
• W2147919015 cites W2042579582 @default.
• W2147919015 cites W2045642546 @default.
• W2147919015 cites W2051567455 @default.
• W2147919015 cites W2082998571 @default.
• W2147919015 cites W2096476766 @default.
• W2147919015 cites W2100126581 @default.
• W2147919015 cites W2100285257 @default.
• W2147919015 cites W2100366750 @default.
• W2147919015 cites W2103384804 @default.
• W2147919015 cites W2107364505 @default.
• W2147919015 cites W2111464846 @default.
• W2147919015 cites W2113880496 @default.
• W2147919015 cites W2116794461 @default.
• W2147919015 cites W2120987573 @default.
• W2147919015 cites W2122567752 @default.
• W2147919015 cites W2127063318 @default.
• W2147919015 cites W2129629034 @default.
• W2147919015 cites W2135037409 @default.
• W2147919015 cites W2136186113 @default.
• W2147919015 cites W2139596056 @default.
• W2147919015 cites W2146139320 @default.
• W2147919015 cites W2153631681 @default.
• W2147919015 cites W2166427367 @default.
• W2147919015 cites W2336541137 @default.
• W2147919015 cites W33368611 @default.
• W2147919015 cites W4297940007 @default.
• W2147919015 doi "https://doi.org/10.1128/cdli.6.5.665-670.1999" @default.
• W2147919015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/95751" @default.
• W2147919015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10473514" @default.
• W2147919015 hasPublicationYear "1999" @default.
• W2147919015 type Work @default.
• W2147919015 sameAs 2147919015 @default.
• W2147919015 citedByCount "11" @default.
• W2147919015 countsByYear W21479190152013 @default.
• W2147919015 crossrefType "journal-article" @default.
• W2147919015 hasAuthorship W2147919015A5021310794 @default.
• W2147919015 hasAuthorship W2147919015A5022852723 @default.
• W2147919015 hasAuthorship W2147919015A5045811531 @default.
• W2147919015 hasAuthorship W2147919015A5052271884 @default.
• W2147919015 hasAuthorship W2147919015A5079234292 @default.
• W2147919015 hasBestOaLocation W21479190151 @default.
• W2147919015 hasConcept C10389963 @default.
• W2147919015 hasConcept C104317684 @default.
• W2147919015 hasConcept C133229898 @default.
• W2147919015 hasConcept C135763542 @default.
• W2147919015 hasConcept C145081991 @default.
• W2147919015 hasConcept C147483822 @default.
• W2147919015 hasConcept C159047783 @default.
• W2147919015 hasConcept C159654299 @default.
• W2147919015 hasConcept C203014093 @default.
• W2147919015 hasConcept C2779548794 @default.
• W2147919015 hasConcept C2780651595 @default.
• W2147919015 hasConcept C2780917455 @default.
• W2147919015 hasConcept C31467283 @default.
• W2147919015 hasConcept C45189115 @default.
• W2147919015 hasConcept C55493867 @default.
• W2147919015 hasConcept C86803240 @default.
• W2147919015 hasConcept C89423630 @default.
• W2147919015 hasConceptScore W2147919015C10389963 @default.
• W2147919015 hasConceptScore W2147919015C104317684 @default.
• W2147919015 hasConceptScore W2147919015C133229898 @default.
• W2147919015 hasConceptScore W2147919015C135763542 @default.
• W2147919015 hasConceptScore W2147919015C145081991 @default.
• W2147919015 hasConceptScore W2147919015C147483822 @default.
• W2147919015 hasConceptScore W2147919015C159047783 @default.
• W2147919015 hasConceptScore W2147919015C159654299 @default.
• W2147919015 hasConceptScore W2147919015C203014093 @default.
• W2147919015 hasConceptScore W2147919015C2779548794 @default.

• next