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• W2148003925 abstract "Immunological ReviewsVolume 52, Issue 1 p. 75-88 Control of Idiotope Expression by Monoclonal Anti-Idiotope Antibodies Garnett Kelsoe, Garnett Kelsoe Institute for Genetics, University of Cologne, Weyertal 121, D-5000 Köln 41, Federal Republic of Germany.Search for more papers by this authorMichael Reth, Michael Reth Institute for Genetics, University of Cologne, Weyertal 121, D-5000 Köln 41, Federal Republic of Germany.Search for more papers by this authorKlaus Rajewsky, Klaus Rajewsky Institute for Genetics, University of Cologne, Weyertal 121, D-5000 Köln 41, Federal Republic of Germany.Search for more papers by this author Garnett Kelsoe, Garnett Kelsoe Institute for Genetics, University of Cologne, Weyertal 121, D-5000 Köln 41, Federal Republic of Germany.Search for more papers by this authorMichael Reth, Michael Reth Institute for Genetics, University of Cologne, Weyertal 121, D-5000 Köln 41, Federal Republic of Germany.Search for more papers by this authorKlaus Rajewsky, Klaus Rajewsky Institute for Genetics, University of Cologne, Weyertal 121, D-5000 Köln 41, Federal Republic of Germany.Search for more papers by this author First published: October 1980 https://doi.org/10.1111/j.1600-065X.1980.tb00331.xCitations: 85AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Augustin, A. & Cosenza, H. (1976) Expression of new idiotypes following neonatal idiotypic suppression of a dominant clone. Eur. J. Immunol. 6, 497. Berek-Jack, C., Schreier, M. H., Sidman, J. L. Jaton, J. C., Kocher, H. P. & Cosenza, H. (1980) Phosphorylcholine-binding hybridoma proteins of normal and idiotypic suppressed BALB/C mice. I. Characterization and idiotypic analysis. Eur. J. Immunol. In press. Bernard, O., Hozumi, N. & Tonegawa, S. (1978) Sequences of mouse immunoglobulin light chain genes before and after somatic changes. Cell 15, 1133. Cohn, M., Blomberg, B., Geckler, W., Raschke, W., Riblet, R. & Weigert, M. (1974) First order considerations in analyzing the generator of diversity. In The Immune System. Genes. Receptors, and Signals, eds. E. E. Sercarz, A. R. Williamson & C. F. Fox, p. 89, Academic Press, New York . Cosenza, H., Julius, M. H. & Augustin, A. A. (1977) Idiotypes as variable region markers: Analogies between receptors on phosphorylcholine-specific T and B lymphocytes. Immunol. Rev. 34, 3. Eichmann, K. (1974) Idiotype suppression. I. Influence of the dose and of the effector functions of anti-idiotypic antibody on the production of an idiotype. Eur. J. Immunol. 4, 296. Eichmann, K. (1975) Idiotype suppression. II. Amplification of a suppressor T cell with anti-idiotypic activity. Eur. J. Immunol. 5, 511. Eichmann, K. (1979) Expression and function of idiotypes on lymphocytes. Adv. Immunol. 25, 195. Eichmann, K. & Rajewsky, K. (1975) Induction of T and B cell immunity by anti-idiotypic antibody. Eur. J. Immunol. 5, 661. Imanishi-Kari, T., Rajnavölgyi, E., Takemori, T., Jack, R. S. & Rajewsky, K. (1979) The effect of light chain gene expression on the inheritance of an idiotype associated with primary anti-(4-hydroxy-3-nitrophenyi)acetyl (NP) antibodies. Eur. J. Immunol. 9, 324. Imanishi-Kari, T., Reth, M., Hämmerling, G. J. & Rajewsky, K. (1978) Analysis of V gene expression in the immune response by cell fusion. In Curr Top. Microbiol Immunol. Vol. 81 Lymphocyte Hybridomas, eds. F. Melchers, M. Potter & N. Warner, p. 20. Springer-Verlag. Berlin, Heidelberg . Imanishi, T. & Mäkelä, O. (1973) Strain differences in the fine specificity of mouse anti-hapten antibodies. Eur. J. Immunol. 3, 323. Jack, R. S., Imanishi-Kari, T. & Rajewsky, K. (1977) Idiotypic analysis of the response of C57BL/6 mice to the (4-bydroxy-3-nitrophenyl)acetyl group, Eur. J. Immunol. 8, 559. Jerne, N. K. (1974) Towards a network theory of the immune system. Ann. Immunol. (Inst. Pasteur) 125C, 373. Julius, M. H., Augustin, A. A, & Consenza, H. (1977) Regulation of idiotypes expressed on receptors of phosphorylcholine-specific T and B lymphocytes. In Regulatory Genetics of the Immune System (ICN-UCLA Symposia on Molecular and Cellular Biology), eds. E. E. Sercarz, L.A. Herzenberg, & C. F. Fox, Vol. 6, p. 179, Academic Press, New York . Karjalainen, K. & Mäkelä. O. (1978) A Mendelian idiotype is demonstrable in the heteroclitic anti-NP antibodies of the mouse, Eur. J. Immunol. 8, 105. Kearney, J. F., Radbruch, A., Liesegang, B. & Rajewsky, K. (1979) A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J. Immunol. 123, 1548. Köhler, G. & Milstein, C. (1975) Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256, 495. Kohler, H., Richardson, B. C., Rowley, D. A. & Smyk, S. (1977) Immune response to phosphorylcholine. III. Requirement of the Fe portion and equal effectiveness of IgG subclasses in antireceptor antibody-induced suppression. J. Immunol. 119, 1979. Mäkelä, O. & Karjalainen, K. (1977) Inherited immunoglobulin idiotypes of the mouse. Transplant. Rev. 34, 119. Marshak-Rothstein, A., Siekevitz, M., Mudgett-Hunter, M., Margolies, M. N. & Gefter, M. L. (1980) Hybridoma proteins expressing the predominant idiotype of the anti-azophenylarsenate response in the A/J mouse. Proc. nat. Acad. Sci. (USA) In press. Rajewsky, K., Hämmerling, G. J., Black, S. J., Berek, C. & Eichmann, K. (1976) T lymphocyte receptor analysis by anti-idiotypic stimulation. In The Role of Products of the Histo-compatibility Gene Complex in Immune Responses, eds. D. H. Katz & B. Benacerraf, p, 445. Academic Press, New York . Rao, D N, Rudikoff, S., Krutzsch, H. & Potter, M. (1979) Structural evidence for independent joining region gene in immunoglobulin heavy chains from antigalactan myeloma proteins and Its potential role in generating diversity in complementarity-determining regions. Proc. nat. Acad. Sci. USA 76, 2890. Reth, M., Hammerling, G. J. & Rajewsky, K. (1978) Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion. I. Characterization of antibody families in the primary and hyperimmune response. Eur. J. Immunol. 8, 393. Reth, M., Imanishi-Kari, T., Jack, R. S., Cramer, M., Krawinkel, U., Hämmerling, G. J. & Rajewsky, K. (1977) The variable portion of T and B cell receptors for antigen; Binding sites for the hapten 4-hydroxy-3-nitro-phenacetyl in C57BL/6 mice. In Regulatory Genetics of the Immune System (ICN-UCLA Symposia on Molecular and Cellular Biology), eds. E.E. Sercarz, L. A. Herzenberg & C. F. Fox, Vol. 6, p. 139. Academic Press. New York . Reth, M., Imanishi-Kari, T. & Rajewsky, K. (1979) Analysis of the repertoire of anti-NP antibodies in C57BL/6 mice by cell fusion, II, Characterization of idiotopes by monoclonal anti-idiotope antibodies. Eur. J. Immunol. 9, 1004. Sakano, H., Hüppi, K., Heinrich, G., & Tonegawa, S. (1979) Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature 280, 288. Schilling, J., Clearinger, B., Davie, J. M. & Hood, L. (1980) Amino acid sequence of homogenous antibodies to dextran and DNA rearrangements in heavy chain V-region gene segments. Nature 283, 35. Scidmann, J. G., Max, E. E, & Leder, P. (1979) A K-immunoglobulin gene is formed by site-specific recombination without further somatic mutation. Nature 280, 370. Seppälä. I. & Eichmann, K. (1979) Induction and characterization of isogeneic anti-idiotypic antibodies to BALB/c myeloma S1 17; lack of reactivity with major idiolypic determinants. Eur. J. Immunol. 9, 243. Trenkner, E. & Riblet, R. (1975) Induction of antiphosphorylcholine antibody formation by anti-idiotypic antibodies. J. exp. med. 142, 1121. Weigert, M. & Potter, M. (1977) Antibody variable region genetics: Summary and abstracts of the homogeneous immunoglobulin workshop VII (April 1976. Bethesda, MD). Immunogenetics 4, 401. Weigert, M. & Riblet, R. (1978) The genetic control of antibody variable regions in the mouse. Springer Semin. Immunopathol. 1, 133. Citing Literature Volume52, Issue1October 1980Pages 75-88 ReferencesRelatedInformation" @default.
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