FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148022618> ?p ?o ?g. }

• W2148022618 endingPage "718" @default.
• W2148022618 startingPage "709" @default.
• W2148022618 abstract "We have examined the effects of the pituitary gonadotropins on expression of the progesterone receptor (PR) gene in rat ovary and in granulosa cell cultures. Both gonadotropins (LH/hCG and FSH) rapidly induce PR mRNA expression in the granulosa cells of preovulatory follicles in vivo. Gonadotropins also effectively induce PR mRNA expression in primary cultures of rat granulosa cells, and this action can be mimicked by agents that elevate intracellular cAMP (forskolin or 8-bromo-cAMP). Estrogen does not induce PR mRNA expression in these cells. The cAMP-induced PR mRNA expression in rat granulosa cells is blocked by an inhibitor of transcription, but not by an inhibitor of protein synthesis. Structural characterization of the rat PR gene 5'-flanking region indicates that the proximal promoter does not contain a consensus cAMP response element. However, when luciferase fusion genes containing a 1375-basepair rat PR gene promoter were transiently transfected into rat granulosa cells, luciferase activity could be stimulated several-fold by hCG or forskolin, but not by estrogen. These results indicate that gonadotropins, most likely acting through a pathway mediated by cAMP, are able to stimulate transcription of the PR gene in rat granulosa cells and suggest a mechanism for regulating the intraovarian actions of progesterone." @default.
• W2148022618 created "2016-06-24" @default.
• W2148022618 creator A5055696858 @default.
• W2148022618 creator A5063142526 @default.
• W2148022618 date "1994-02-01" @default.
• W2148022618 modified "2023-09-27" @default.
• W2148022618 title "Regulation of the progesterone receptor gene by gonadotropins and cyclic adenosine 3',5'-monophosphate in rat granulosa cells." @default.
• W2148022618 cites W1530523756 @default.
• W2148022618 cites W1829587598 @default.
• W2148022618 cites W1979801990 @default.
• W2148022618 cites W2006000426 @default.
• W2148022618 cites W2008901904 @default.
• W2148022618 cites W2033805578 @default.
• W2148022618 cites W2041219190 @default.
• W2148022618 cites W2052636645 @default.
• W2148022618 cites W2065647047 @default.
• W2148022618 cites W2068673201 @default.
• W2148022618 cites W2071479712 @default.
• W2148022618 cites W2073505399 @default.
• W2148022618 cites W2093204677 @default.
• W2148022618 cites W2097794242 @default.
• W2148022618 cites W2105612963 @default.
• W2148022618 cites W2109102732 @default.
• W2148022618 cites W2124685759 @default.
• W2148022618 cites W2124965472 @default.
• W2148022618 cites W2146467003 @default.
• W2148022618 cites W2149573140 @default.
• W2148022618 doi "https://doi.org/10.1210/endo.134.2.8299566" @default.
• W2148022618 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8299566" @default.
• W2148022618 hasPublicationYear "1994" @default.
• W2148022618 type Work @default.
• W2148022618 sameAs 2148022618 @default.
• W2148022618 citedByCount "98" @default.
• W2148022618 countsByYear W21480226182012 @default.
• W2148022618 countsByYear W21480226182013 @default.
• W2148022618 countsByYear W21480226182014 @default.
• W2148022618 countsByYear W21480226182015 @default.
• W2148022618 countsByYear W21480226182016 @default.
• W2148022618 countsByYear W21480226182017 @default.
• W2148022618 countsByYear W21480226182018 @default.
• W2148022618 countsByYear W21480226182020 @default.
• W2148022618 countsByYear W21480226182022 @default.
• W2148022618 countsByYear W21480226182023 @default.
• W2148022618 crossrefType "journal-article" @default.
• W2148022618 hasAuthorship W2148022618A5055696858 @default.
• W2148022618 hasAuthorship W2148022618A5063142526 @default.
• W2148022618 hasConcept C104317684 @default.
• W2148022618 hasConcept C121608353 @default.
• W2148022618 hasConcept C126322002 @default.
• W2148022618 hasConcept C134018914 @default.
• W2148022618 hasConcept C150194340 @default.
• W2148022618 hasConcept C170493617 @default.
• W2148022618 hasConcept C24998067 @default.
• W2148022618 hasConcept C2776668983 @default.
• W2148022618 hasConcept C2777164284 @default.
• W2148022618 hasConcept C2777203538 @default.
• W2148022618 hasConcept C2778324911 @default.
• W2148022618 hasConcept C2778782382 @default.
• W2148022618 hasConcept C2779276759 @default.
• W2148022618 hasConcept C530470458 @default.
• W2148022618 hasConcept C54009773 @default.
• W2148022618 hasConcept C54355233 @default.
• W2148022618 hasConcept C55493867 @default.
• W2148022618 hasConcept C71315377 @default.
• W2148022618 hasConcept C71924100 @default.
• W2148022618 hasConcept C81885089 @default.
• W2148022618 hasConcept C84606932 @default.
• W2148022618 hasConcept C86803240 @default.
• W2148022618 hasConcept C98717036 @default.
• W2148022618 hasConceptScore W2148022618C104317684 @default.
• W2148022618 hasConceptScore W2148022618C121608353 @default.
• W2148022618 hasConceptScore W2148022618C126322002 @default.
• W2148022618 hasConceptScore W2148022618C134018914 @default.
• W2148022618 hasConceptScore W2148022618C150194340 @default.
• W2148022618 hasConceptScore W2148022618C170493617 @default.
• W2148022618 hasConceptScore W2148022618C24998067 @default.
• W2148022618 hasConceptScore W2148022618C2776668983 @default.
• W2148022618 hasConceptScore W2148022618C2777164284 @default.
• W2148022618 hasConceptScore W2148022618C2777203538 @default.
• W2148022618 hasConceptScore W2148022618C2778324911 @default.
• W2148022618 hasConceptScore W2148022618C2778782382 @default.
• W2148022618 hasConceptScore W2148022618C2779276759 @default.
• W2148022618 hasConceptScore W2148022618C530470458 @default.
• W2148022618 hasConceptScore W2148022618C54009773 @default.
• W2148022618 hasConceptScore W2148022618C54355233 @default.
• W2148022618 hasConceptScore W2148022618C55493867 @default.
• W2148022618 hasConceptScore W2148022618C71315377 @default.
• W2148022618 hasConceptScore W2148022618C71924100 @default.
• W2148022618 hasConceptScore W2148022618C81885089 @default.
• W2148022618 hasConceptScore W2148022618C84606932 @default.
• W2148022618 hasConceptScore W2148022618C86803240 @default.
• W2148022618 hasConceptScore W2148022618C98717036 @default.
• W2148022618 hasIssue "2" @default.
• W2148022618 hasLocation W21480226181 @default.
• W2148022618 hasLocation W21480226182 @default.
• W2148022618 hasOpenAccess W2148022618 @default.
• W2148022618 hasPrimaryLocation W21480226181 @default.
• W2148022618 hasRelatedWork W1981477956 @default.

• next