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• W2148260799 abstract "The antihyperglycaemic and hypolipidaemic effects of the methanolic extract of Caralluma tuberculata were investigated in streptozotocin (STZ)-induced diabetic rats. The antihyperglycaemic activity was assessed by the reduction in fasting blood glucose (54% at 4th week) and the peak of blood glucose at 120 min of an oral glucose tolerance test in diabetic rats. Further, the tested extract also increased plasma insulin by 206.8%. The hypolipidaemic action of the extract was evident by the significant decrease in the levels of total cholesterol, triglycerides and LDL-cholesterol by 41.5%, 36.7% and 49.1%, respectively, compared to diabetic rat values. Interestingly, the extract increased the cardio-protective lipid HDL-cholesterol by 147.97% as compared to diabetic rat value. The present data suggests that the methanolic extract of C. tuberculata has both antihyperglycaemic and hypolipidaemic effects in STZ-induced diabetic rats that may need further studies to be used in the management of diabetes and associated hyperlipedaemia." @default.
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• W2148260799 date "2011-07-01" @default.
• W2148260799 modified "2023-10-16" @default.
• W2148260799 title "Antihyperglycaemic and hypolipidaemic effects of the methanolic extract of<i>Caralluma tuberculata</i>in streptozotocin-induced diabetic rats" @default.
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• W2148260799 doi "https://doi.org/10.1080/14786419.2010.490782" @default.
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