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- W2148373407 abstract "This paper presents the synthesis and characterization of a mesoporous silica obtained from rice husk; This silica was used as a new carrier for griseofulvin (antifungal). This silica showed a maximum of 15% by weight of drug adsorption; Studies of adsorption and desorption of N2 suggest silicas drug adsorption mostly goes into the pores of the material. The maximum rate of release of the drug adsorbed on the silica at pH 7 was 60%. Moreover, the study of drug - SiO2 system in controlling the growth of C. albicans observing control of 90 % in the growth of the fungus for a maximum period of 6 h, with minimum dosages of 750 mg of SiO2-drug corresponding to 112.5 mg of drug. Furthermore, a null pharmacological activity both griseofulvin and silica separately administered was observed. The results indicated that the SiO2- rice can be an excellent carrier for griseofulvin. Keyword— SiO2-farmaco, biogenica, control, crecimiento, griseofulvina." @default.
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- W2148373407 date "2014-07-21" @default.
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- W2148373407 title "Estudio del control de crecimiento de C. albicans con sistemas de griseofulvina adsorbida en SiO 2 - porosa obtenida de la cascara de arroz" @default.
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