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- W2148406502 abstract "Abstract Although most of what is known about the biology and function of arachidonic acid metabolites comes from the study of mammalian biology, these compounds can also be produced by lower eukaryotes, including yeasts and other fungi. It is also in this group of organisms that the least is known about the metabolic pathways leading to the production of these compounds as well as the functions of these compounds in the biology of fungi and yeasts. This review will deal with the discovery of oxylipins from polyunsaturated fatty acids, and more specifically the arachidonic acid derived eicosanoids, such as 3-hydroxy eicosatetraenoic acid, prostaglandin F 2α and prostaglandin E 2 , in yeasts starting in the early 1990s. This review will also focus on what is known about the metabolic pathways and/or proteins involved in the production of these compounds in pathogenic yeasts. The possible roles of these compounds in the biology, including the pathology, of these organisms will be discussed." @default.
- W2148406502 created "2016-06-24" @default.
- W2148406502 creator A5015489111 @default.
- W2148406502 creator A5040718542 @default.
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- W2148406502 date "2012-08-08" @default.
- W2148406502 modified "2023-10-14" @default.
- W2148406502 title "Arachidonic acid metabolites in pathogenic yeasts" @default.
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- W2148406502 doi "https://doi.org/10.1186/1476-511x-11-100" @default.
- W2148406502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3475069" @default.
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