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- W2148436610 abstract "<h2>Abstract</h2><h3>Background</h3> Commonly the frequency of international normalized ratio (INR) monitoring with a conventional laboratory test in stable patients is once a month. When using a dedicated personal device for INR assessment, the frequency may be increased to two or more times a month. <h3>Objective</h3> To show that INR assessed by self-measurement at home is reliable and feasible in the mid-term and improves medical care. <h3>Patients and methods</h3> All patients in the study on INR self-measurement (clinical trial.gov: NCT00925197), conducted between 2004 and 2007, were re-contacted for mid-term follow-up. One hundred and seventy eight out of 192 patients who participated in the study answered a questionnaire. The average follow-up time was 4.2years (±1) for the self-measurement group and 4.9years (±1) for the laboratory-analyzed control group. <h3>Results</h3> Only 26 patients (group A) continued to use INR self-measurement to monitor treatment with vitamin K antagonists (VKA). The main reasons to stop INR self-measurement were its high cost and difficulty in obtaining strips. There were significantly fewer bleeding complications (p=0.04) and complications related to VKA (p=0.01) in self-measured patients compared to the control group. Feelings of security and quality of life were also significantly better (p=0.002) for self-measured patients. <h3>Conclusion</h3> Many patients with a mechanical heart valve, who self-measured INR, continue to use this method for their follow-up because of its positive effects on their health and quality of life." @default.
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- W2148436610 date "2014-02-01" @default.
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- W2148436610 title "Mid-term results of self-testing of the international normalized ratio in adults with a mechanical heart valve" @default.
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- W2148436610 doi "https://doi.org/10.1016/j.thromres.2013.09.013" @default.
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