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- W2148445154 abstract "A strategy of full-site occupancy and stereospecific recognition in the triphosphate subsite was used to specifically inhibit two protein kinases HER-2 and HER-4 from the EGFR family. The SAR profiles of a panel of adenosine-anchored bicyclic heterocycles against HER-2 and HER-4 indicated that specificity can be derived for highly homologous protein kinases from stereospecific recognition in the triphosphate-subsite." @default.
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- W2148445154 date "2003-10-01" @default.
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- W2148445154 title "Adenosine-anchored triphosphate subsite probing: distinguishing between HER-2 and HER-4 tyrosine protein kinases" @default.
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- W2148445154 doi "https://doi.org/10.1016/s0960-894x(03)00761-3" @default.
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