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- W2148496622 abstract "Detection of misuse of peptides and proteins as growth promoters is a major issue for sport and food regulatory agencies. The limitations of current analytical detection strategies for this class of compounds, in combination with their efficacy in growth‐promoting effects, make peptide and protein drugs highly susceptible to abuse by either athletes or farmers who seek for products to illicitly enhance muscle growth. Mass spectrometry (MS) for qualitative analysis of peptides and proteins is well‐established, particularly due to tremendous efforts in the proteomics community. Similarly, due to advancements in targeted proteomic strategies and the rapid growth of protein‐based biopharmaceuticals, MS for quantitative analysis of peptides and proteins is becoming more widely accepted. These continuous advances in MS instrumentation and MS‐based methodologies offer enormous opportunities for detection and confirmation of peptides and proteins. Therefore, MS seems to be the method of choice to improve the qualitative and quantitative analysis of peptide and proteins with growth‐promoting properties. This review aims to address the opportunities of MS for peptide and protein analysis in veterinary control and sports‐doping control with a particular focus on detection of illicit growth promotion. An overview of potential peptide and protein targets, including their amino acid sequence characteristics and current MS‐based detection strategies is, therefore, provided. Furthermore, improvements of current and new detection strategies with state‐of‐the‐art MS instrumentation are discussed for qualitative and quantitative approaches. © 2015 Wiley Periodicals, Inc. Mass Spec Rev 34: 571–594, 2015." @default.
- W2148496622 created "2016-06-24" @default.
- W2148496622 creator A5051412631 @default.
- W2148496622 creator A5062415396 @default.
- W2148496622 creator A5082394608 @default.
- W2148496622 creator A5083633698 @default.
- W2148496622 date "2013-12-21" @default.
- W2148496622 modified "2023-10-05" @default.
- W2148496622 title "Current trends in mass spectrometry of peptides and proteins: Application to veterinary and sports-doping control" @default.
- W2148496622 cites W102720024 @default.
- W2148496622 cites W104774753 @default.
- W2148496622 cites W1503704376 @default.
- W2148496622 cites W1518339162 @default.
- W2148496622 cites W1543584393 @default.
- W2148496622 cites W1548224592 @default.
- W2148496622 cites W1893925664 @default.
- W2148496622 cites W1946343641 @default.
- W2148496622 cites W1964203865 @default.
- W2148496622 cites W1968157219 @default.
- W2148496622 cites W1968166904 @default.
- W2148496622 cites W1968742064 @default.
- W2148496622 cites W1971411779 @default.
- W2148496622 cites W1974830441 @default.
- W2148496622 cites W1974921104 @default.
- W2148496622 cites W1975558168 @default.
- W2148496622 cites W1979677540 @default.
- W2148496622 cites W1980240275 @default.
- W2148496622 cites W1981326910 @default.
- W2148496622 cites W1982281137 @default.
- W2148496622 cites W1983312160 @default.
- W2148496622 cites W1984895672 @default.
- W2148496622 cites W1985262375 @default.
- W2148496622 cites W1986273268 @default.
- W2148496622 cites W1989833877 @default.
- W2148496622 cites W1990281642 @default.
- W2148496622 cites W1990895382 @default.
- W2148496622 cites W1991552897 @default.
- W2148496622 cites W1994243355 @default.
- W2148496622 cites W2001474571 @default.
- W2148496622 cites W2001675611 @default.
- W2148496622 cites W2002778277 @default.
- W2148496622 cites W2003162418 @default.
- W2148496622 cites W2004543829 @default.
- W2148496622 cites W2007600529 @default.
- W2148496622 cites W2013710189 @default.
- W2148496622 cites W2013835332 @default.
- W2148496622 cites W2014492028 @default.
- W2148496622 cites W2014754598 @default.
- W2148496622 cites W2014837568 @default.
- W2148496622 cites W2016394687 @default.
- W2148496622 cites W2017375426 @default.
- W2148496622 cites W2017816417 @default.
- W2148496622 cites W2022488157 @default.
- W2148496622 cites W2023055302 @default.
- W2148496622 cites W2023096047 @default.
- W2148496622 cites W2026850118 @default.
- W2148496622 cites W2028933014 @default.
- W2148496622 cites W2029173116 @default.
- W2148496622 cites W2029935277 @default.
- W2148496622 cites W2030655468 @default.
- W2148496622 cites W2030844152 @default.
- W2148496622 cites W2031462738 @default.
- W2148496622 cites W2031609868 @default.
- W2148496622 cites W2032202083 @default.
- W2148496622 cites W2033890956 @default.
- W2148496622 cites W2034001550 @default.
- W2148496622 cites W2034465974 @default.
- W2148496622 cites W2034608454 @default.
- W2148496622 cites W2035037428 @default.
- W2148496622 cites W2037501897 @default.
- W2148496622 cites W2039692675 @default.
- W2148496622 cites W2040073953 @default.
- W2148496622 cites W2040829733 @default.
- W2148496622 cites W2041615376 @default.
- W2148496622 cites W2043418796 @default.
- W2148496622 cites W2044860700 @default.
- W2148496622 cites W2045865140 @default.
- W2148496622 cites W2046249267 @default.
- W2148496622 cites W2046520841 @default.
- W2148496622 cites W2047769662 @default.
- W2148496622 cites W2048598879 @default.
- W2148496622 cites W2051118435 @default.
- W2148496622 cites W2051930920 @default.
- W2148496622 cites W2052484895 @default.
- W2148496622 cites W2053219779 @default.
- W2148496622 cites W2054888532 @default.
- W2148496622 cites W2056779899 @default.
- W2148496622 cites W2058019808 @default.
- W2148496622 cites W2058906299 @default.
- W2148496622 cites W2059436777 @default.
- W2148496622 cites W2061442101 @default.
- W2148496622 cites W2062014287 @default.
- W2148496622 cites W2062311239 @default.
- W2148496622 cites W2064842327 @default.
- W2148496622 cites W2066322883 @default.
- W2148496622 cites W2066466157 @default.
- W2148496622 cites W2067623853 @default.
- W2148496622 cites W2068481474 @default.