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- W2148522034 abstract "Autoregulation of blood flow has been observed in the denervated carotid bodies of rabbits and cats, using a method which measures the arterial inflow at various perfusion pressures. In almost half of experiments in rabbits, autoregulation was observed. It was abolished by hyperventilation, and by raising the perfusion pressure very high. It has been produced by administering carbon dioxide into the inspired gas. Sympathetic stimulation and adrenaline or noradrenaline reduced carotid body flow, and in one experiment adrenaline lowered the level of flow without abolishing autoregulation. Autoregulation of flow was also observed in the carotid bodies of cats under chloralose, but not when barbiturate anaesthesia was used. The significance of autoregulation of flow for carotid body function, and possible mechanisms causing the phenomenon are discussed. An elaboration of the myogenic hypothesis of autoregulation is proposed." @default.
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- W2148522034 date "1971-10-01" @default.
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- W2148522034 title "Autoregulation of blood flow in the carotid body" @default.
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- W2148522034 doi "https://doi.org/10.1016/0034-5687(71)90062-4" @default.
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