FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148522077> ?p ?o ?g. }

• W2148522077 endingPage "35" @default.
• W2148522077 startingPage "28" @default.
• W2148522077 abstract "Mrp antiporters and their homologues in the cation/proton antiporter 3 family of the Membrane Transporter Database are widely distributed in bacteria. They have major roles in supporting cation and cytoplasmic pH homeostasis in many environmental, extremophilic, and pathogenic bacteria. These antiporters require six or seven hydrophobic proteins that form hetero-oligomeric complexes, while most other cation/proton antiporters require only one membrane protein for their activity. The resemblance of three Mrp subunits to membrane-embedded subunits of the NADH:quinone oxidoreductase of respiratory chains and to subunits of several hydrogenases has raised interest in the evolutionary path and commonalities of their proton-translocating domains. In order to move toward a greater mechanistic understanding of these unusual antiporters and to rigorously demonstrate that they function as secondary antiporters, powered by an imposed proton motive force, we established a method for purification and functional reconstitution of the seven-subunit Mrp antiporter from alkaliphilic Bacillus pseudofirmus OF4. Na(+)/H(+) antiporter activity was demonstrated by a fluorescence-based assay with proteoliposomes in which the Mrp complex was coreconstituted with a bacterial FoF1-ATPase. Proton pumping by the ATPase upon addition of ATP generated a proton motive force across the membranes that powered antiporter activity upon subsequent addition of Na(+)." @default.
• W2148522077 created "2016-06-24" @default.
• W2148522077 creator A5026902813 @default.
• W2148522077 creator A5043105729 @default.
• W2148522077 creator A5060873376 @default.
• W2148522077 creator A5065167441 @default.
• W2148522077 date "2013-10-18" @default.
• W2148522077 modified "2023-10-18" @default.
• W2148522077 title "Purification and Functional Reconstitution of a Seven-Subunit Mrp-Type Na+/H+ Antiporter" @default.
• W2148522077 cites W1550015947 @default.
• W2148522077 cites W1553636470 @default.
• W2148522077 cites W1589442858 @default.
• W2148522077 cites W1967133300 @default.
• W2148522077 cites W1977201784 @default.
• W2148522077 cites W1979460460 @default.
• W2148522077 cites W1983433311 @default.
• W2148522077 cites W1983487087 @default.
• W2148522077 cites W1991716344 @default.
• W2148522077 cites W1994568164 @default.
• W2148522077 cites W1997200285 @default.
• W2148522077 cites W2004181413 @default.
• W2148522077 cites W2005850676 @default.
• W2148522077 cites W2006090861 @default.
• W2148522077 cites W2006643836 @default.
• W2148522077 cites W2006782097 @default.
• W2148522077 cites W2025806229 @default.
• W2148522077 cites W2051311695 @default.
• W2148522077 cites W2052809239 @default.
• W2148522077 cites W2055155126 @default.
• W2148522077 cites W2058570690 @default.
• W2148522077 cites W2065228034 @default.
• W2148522077 cites W2068475311 @default.
• W2148522077 cites W2069902567 @default.
• W2148522077 cites W2070940402 @default.
• W2148522077 cites W2103351028 @default.
• W2148522077 cites W2109731814 @default.
• W2148522077 cites W2110910972 @default.
• W2148522077 cites W2111727847 @default.
• W2148522077 cites W2113755389 @default.
• W2148522077 cites W2120211414 @default.
• W2148522077 cites W2127113854 @default.
• W2148522077 cites W2145740326 @default.
• W2148522077 cites W2146546082 @default.
• W2148522077 cites W2149336336 @default.
• W2148522077 cites W2153572376 @default.
• W2148522077 cites W2155217808 @default.
• W2148522077 cites W2159299078 @default.
• W2148522077 cites W2160179761 @default.
• W2148522077 cites W2161491767 @default.
• W2148522077 cites W2169285480 @default.
• W2148522077 cites W2170841407 @default.
• W2148522077 cites W4214952473 @default.
• W2148522077 cites W4237491373 @default.
• W2148522077 cites W988977465 @default.
• W2148522077 doi "https://doi.org/10.1128/jb.01029-13" @default.
• W2148522077 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3911140" @default.
• W2148522077 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24142251" @default.
• W2148522077 hasPublicationYear "2013" @default.
• W2148522077 type Work @default.
• W2148522077 sameAs 2148522077 @default.
• W2148522077 citedByCount "20" @default.
• W2148522077 countsByYear W21485220772015 @default.
• W2148522077 countsByYear W21485220772016 @default.
• W2148522077 countsByYear W21485220772017 @default.
• W2148522077 countsByYear W21485220772018 @default.
• W2148522077 countsByYear W21485220772019 @default.
• W2148522077 countsByYear W21485220772020 @default.
• W2148522077 countsByYear W21485220772021 @default.
• W2148522077 countsByYear W21485220772022 @default.
• W2148522077 crossrefType "journal-article" @default.
• W2148522077 hasAuthorship W2148522077A5026902813 @default.
• W2148522077 hasAuthorship W2148522077A5043105729 @default.
• W2148522077 hasAuthorship W2148522077A5060873376 @default.
• W2148522077 hasAuthorship W2148522077A5065167441 @default.
• W2148522077 hasBestOaLocation W21485220771 @default.
• W2148522077 hasConcept C104292427 @default.
• W2148522077 hasConcept C104317684 @default.
• W2148522077 hasConcept C112243037 @default.
• W2148522077 hasConcept C12554922 @default.
• W2148522077 hasConcept C128892225 @default.
• W2148522077 hasConcept C144647389 @default.
• W2148522077 hasConcept C171357686 @default.
• W2148522077 hasConcept C181199279 @default.
• W2148522077 hasConcept C23265538 @default.
• W2148522077 hasConcept C2910532024 @default.
• W2148522077 hasConcept C2992012372 @default.
• W2148522077 hasConcept C41625074 @default.
• W2148522077 hasConcept C523546767 @default.
• W2148522077 hasConcept C54355233 @default.
• W2148522077 hasConcept C55493867 @default.
• W2148522077 hasConcept C57181701 @default.
• W2148522077 hasConcept C86803240 @default.
• W2148522077 hasConceptScore W2148522077C104292427 @default.
• W2148522077 hasConceptScore W2148522077C104317684 @default.
• W2148522077 hasConceptScore W2148522077C112243037 @default.
• W2148522077 hasConceptScore W2148522077C12554922 @default.
• W2148522077 hasConceptScore W2148522077C128892225 @default.
• W2148522077 hasConceptScore W2148522077C144647389 @default.

• next