FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148596844> ?p ?o ?g. }

• W2148596844 endingPage "851" @default.
• W2148596844 startingPage "835" @default.
• W2148596844 abstract "This review examines selected areas of cardiovascular physiology where there have been impressive gains of knowledge and indicates fertile areas for future research. Because arterial blood is usually fully saturated with oxygen, increasing cardiac output is the only means for transferring substantially more oxygen to tissues. Consequently, any behavioural or environmental change that alters oxygen uptake typically involves a change in cardiac output, which in fishes can amount to a threefold change. During exercise, not all fishes necessarily have the same ability as salmonids to increase cardiac output by increasing stroke volume; they rely more on increases in heart rate instead. The benefits associated with increasing cardiac output via stroke volume or heart rate are unclear. Regardless, all fishes examined so far show an exquisite cardiac sensitivity to filling pressure and the cellular basis for this heightened cardiac stretch sensitivity in fish is being unraveled. Even so, a fully integrated picture of cardiovascular functioning in fishes is hampered by a dearth of studies on venous circulatory control. Potent positive cardiac inotropy involves stimulation of sarcolemmal β-adrenoceptors, which increases the peak trans-sarcolemmal current for calcium and the intracellular calcium transient available for binding to troponin C. However, adrenergic sensitivity is temperature-dependent in part through effects on membrane currents and receptor density. The membrane currents contributing to the pacemaker action potential are also being studied but remain a prime area for further study. Why maximum heart rate is limited to a low rate in most fishes compared with similar-sized mammals, even when Q 10 effects are considered, remains a mystery. Fish hearts have up to three oxygen supply routes. The degree of coronary capillarization circulation is of primary importance to the compact myocardium, unlike the spongy myocardium, where venous oxygen partial pressure appears to be the critical factor in terms of oxygen delivery. Air-breathing fishes can boost the venous oxygen content and oxygen partial pressure by taking an air breath, thereby providing a third myocardial oxygen supply route that perhaps compensates for the potentially precarious supply to the spongy myocardium during hypoxia and exercise. In addition to venous hypoxemia, acidemia and hyperkalemia can accompany exhaustive exercise and acute warming, perhaps impairing the heart were it not for a cardiac protection mechanism afforded by β-adrenergic stimulation. With warming, however, a mismatch between an animal’s demand for oxygen (a Q 10 effect) and the capacity of the circulatory and ventilatory systems to delivery this oxygen develops beyond an optimum temperature. At temperature extremes in salmon, it is proposed that detrimental changes in venous blood composition, coupled with a breakdown of the cardiac protective mechanism, is a potential mechanism to explain the decline in maximum and cardiac arrhythmias that are observed. Furthermore, the fall off in scope for heart rate and cardiac output is used to explain the decrease in aerobic scope above the optimum temperature, which may then explain the field observation that adult sockeye salmon ( Oncorhynchus nerka (Walbaum in Artedi, 1792)) have difficulty migrating to their spawning area at temperatures above their optimum. Such mechanistic linkages to lifetime fitness, whether they are cardiovascular or not, should assist with predictions in this era of global climate change." @default.
• W2148596844 created "2016-06-24" @default.
• W2148596844 creator A5047650276 @default.
• W2148596844 creator A5049798624 @default.
• W2148596844 creator A5077450789 @default.
• W2148596844 creator A5077459501 @default.
• W2148596844 date "2009-10-01" @default.
• W2148596844 modified "2023-10-18" @default.
• W2148596844 title "Fish cardiorespiratory physiology in an era of climate changeThe present review is one of a series of occasional review articles that have been invited by the Editors and will feature the broad range of disciplines and expertise represented in our Editorial Advisory Board." @default.
• W2148596844 cites W1238563228 @default.
• W2148596844 cites W1503900815 @default.
• W2148596844 cites W1513626006 @default.
• W2148596844 cites W1673483003 @default.
• W2148596844 cites W1848568106 @default.
• W2148596844 cites W1913374361 @default.
• W2148596844 cites W1921232173 @default.
• W2148596844 cites W1923649370 @default.
• W2148596844 cites W1927674724 @default.
• W2148596844 cites W1953940091 @default.
• W2148596844 cites W1955316225 @default.
• W2148596844 cites W1964965105 @default.
• W2148596844 cites W1967098305 @default.
• W2148596844 cites W1968963998 @default.
• W2148596844 cites W1969381979 @default.
• W2148596844 cites W1974677367 @default.
• W2148596844 cites W1974782955 @default.
• W2148596844 cites W1976729380 @default.
• W2148596844 cites W1981812869 @default.
• W2148596844 cites W1985692345 @default.
• W2148596844 cites W1993811257 @default.
• W2148596844 cites W1995467600 @default.
• W2148596844 cites W1998644905 @default.
• W2148596844 cites W1999305924 @default.
• W2148596844 cites W2010211043 @default.
• W2148596844 cites W2013067980 @default.
• W2148596844 cites W2014977251 @default.
• W2148596844 cites W2015327658 @default.
• W2148596844 cites W2025407784 @default.
• W2148596844 cites W2025426319 @default.
• W2148596844 cites W2035648884 @default.
• W2148596844 cites W2036274765 @default.
• W2148596844 cites W2037884819 @default.
• W2148596844 cites W2040659947 @default.
• W2148596844 cites W2047009709 @default.
• W2148596844 cites W2047986381 @default.
• W2148596844 cites W2048682842 @default.
• W2148596844 cites W2052049091 @default.
• W2148596844 cites W2053110663 @default.
• W2148596844 cites W2056066723 @default.
• W2148596844 cites W2058667701 @default.
• W2148596844 cites W2059667297 @default.
• W2148596844 cites W2060213223 @default.
• W2148596844 cites W2061141141 @default.
• W2148596844 cites W2063607699 @default.
• W2148596844 cites W2063686985 @default.
• W2148596844 cites W2065510122 @default.
• W2148596844 cites W2068568379 @default.
• W2148596844 cites W2071099171 @default.
• W2148596844 cites W2076344992 @default.
• W2148596844 cites W2076715987 @default.
• W2148596844 cites W2079087232 @default.
• W2148596844 cites W2081114784 @default.
• W2148596844 cites W2081781056 @default.
• W2148596844 cites W2083061903 @default.
• W2148596844 cites W2083395355 @default.
• W2148596844 cites W2088101221 @default.
• W2148596844 cites W2092036283 @default.
• W2148596844 cites W2092346296 @default.
• W2148596844 cites W2093714195 @default.
• W2148596844 cites W2097613054 @default.
• W2148596844 cites W2100828200 @default.
• W2148596844 cites W2104762462 @default.
• W2148596844 cites W2107281697 @default.
• W2148596844 cites W2109115928 @default.
• W2148596844 cites W2109503246 @default.
• W2148596844 cites W2114417613 @default.
• W2148596844 cites W2115435507 @default.
• W2148596844 cites W2115571172 @default.
• W2148596844 cites W2119027736 @default.
• W2148596844 cites W2120318456 @default.
• W2148596844 cites W2121906467 @default.
• W2148596844 cites W2123032544 @default.
• W2148596844 cites W2125171769 @default.
• W2148596844 cites W2125505135 @default.
• W2148596844 cites W2126329285 @default.
• W2148596844 cites W2127057175 @default.
• W2148596844 cites W2127451354 @default.
• W2148596844 cites W2130272397 @default.
• W2148596844 cites W2134257996 @default.
• W2148596844 cites W2134419893 @default.
• W2148596844 cites W2134899273 @default.
• W2148596844 cites W2135528343 @default.
• W2148596844 cites W2136228484 @default.
• W2148596844 cites W2137631906 @default.
• W2148596844 cites W2139696468 @default.
• W2148596844 cites W2142373229 @default.
• W2148596844 cites W2148725662 @default.
• W2148596844 cites W2150423161 @default.

• next