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- W2148607599 abstract "In the past, various approaches have been developed to detect adverse effects of pollutants on the thyroid of vertebrates, most of these with special emphasis on the South African clawed frog, Xenopus laevis. Although fish are primarily affected by thyroid-disrupting chemicals, studies into alterations of the thyroid of fish are scarce. Therefore, effects of the reference compound propylthiouracil on histopathology of the thyroid axis were analyzed in a modified early life-stage test with zebrafish (Danio rerio) exposed to propylthiouracil. The test substance induced dose-dependent alterations of thyroidal tissue concomitant with increases in the number of surrounding blood vessels. Despite this massive proliferation of the thyroid, zebrafish were not able to maintain thyroxin concentrations. The pituitary was affected displaying significant alterations in thyroid-stimulating hormone cell counts. Quantitative evaluation of pituitary surface areas revealed a dose-dependent increase of adenohypophyseal tissue. Distinct histopathological effects may contribute to a more easy identification and interpretation of alterations induced by thyroid-disrupting chemicals." @default.
- W2148607599 created "2016-06-24" @default.
- W2148607599 creator A5042450452 @default.
- W2148607599 creator A5070267774 @default.
- W2148607599 date "2011-01-01" @default.
- W2148607599 modified "2023-09-29" @default.
- W2148607599 title "Alterations along the Hypothalamic-Pituitary-Thyroid Axis of the Zebrafish (<i>Danio rerio</i>) after Exposure to Propylthiouracil" @default.
- W2148607599 cites W144254091 @default.
- W2148607599 cites W1495400959 @default.
- W2148607599 cites W1513569516 @default.
- W2148607599 cites W1638168008 @default.
- W2148607599 cites W1664924085 @default.
- W2148607599 cites W1965900034 @default.
- W2148607599 cites W1966110694 @default.
- W2148607599 cites W1967419775 @default.
- W2148607599 cites W1967575722 @default.
- W2148607599 cites W1972238619 @default.
- W2148607599 cites W1973257953 @default.
- W2148607599 cites W1977920168 @default.
- W2148607599 cites W1979292473 @default.
- W2148607599 cites W1979426376 @default.
- W2148607599 cites W1981769026 @default.
- W2148607599 cites W1984711327 @default.
- W2148607599 cites W1989157785 @default.
- W2148607599 cites W1989649132 @default.
- W2148607599 cites W1990137921 @default.
- W2148607599 cites W2001508977 @default.
- W2148607599 cites W2001896136 @default.
- W2148607599 cites W2003889007 @default.
- W2148607599 cites W2004595719 @default.
- W2148607599 cites W2005192674 @default.
- W2148607599 cites W2008644667 @default.
- W2148607599 cites W2013826707 @default.
- W2148607599 cites W2023892207 @default.
- W2148607599 cites W2026302267 @default.
- W2148607599 cites W2026484090 @default.
- W2148607599 cites W2028384573 @default.
- W2148607599 cites W2028644455 @default.
- W2148607599 cites W2029636708 @default.
- W2148607599 cites W2031192188 @default.
- W2148607599 cites W2035189205 @default.
- W2148607599 cites W2036546672 @default.
- W2148607599 cites W2038487944 @default.
- W2148607599 cites W2040915151 @default.
- W2148607599 cites W2042961921 @default.
- W2148607599 cites W2044959308 @default.
- W2148607599 cites W2047735796 @default.
- W2148607599 cites W2048565438 @default.
- W2148607599 cites W2053977487 @default.
- W2148607599 cites W2054213101 @default.
- W2148607599 cites W2056754362 @default.
- W2148607599 cites W2060309278 @default.
- W2148607599 cites W2060940665 @default.
- W2148607599 cites W2064950621 @default.
- W2148607599 cites W2065379855 @default.
- W2148607599 cites W2066084087 @default.
- W2148607599 cites W2067490033 @default.
- W2148607599 cites W2069072867 @default.
- W2148607599 cites W2070936807 @default.
- W2148607599 cites W2073447884 @default.
- W2148607599 cites W2074988774 @default.
- W2148607599 cites W2079596704 @default.
- W2148607599 cites W2087165967 @default.
- W2148607599 cites W2087168987 @default.
- W2148607599 cites W2088708637 @default.
- W2148607599 cites W2089164938 @default.
- W2148607599 cites W2094017054 @default.
- W2148607599 cites W2096093850 @default.
- W2148607599 cites W2097336373 @default.
- W2148607599 cites W2098277494 @default.
- W2148607599 cites W2098597135 @default.
- W2148607599 cites W2100074717 @default.
- W2148607599 cites W2105012459 @default.
- W2148607599 cites W2105270067 @default.
- W2148607599 cites W2106608954 @default.
- W2148607599 cites W2109401564 @default.
- W2148607599 cites W2109429198 @default.
- W2148607599 cites W2110634607 @default.
- W2148607599 cites W2113425082 @default.
- W2148607599 cites W2114437251 @default.
- W2148607599 cites W2117184248 @default.
- W2148607599 cites W2117306616 @default.
- W2148607599 cites W2127911529 @default.
- W2148607599 cites W2135172604 @default.
- W2148607599 cites W2135719238 @default.
- W2148607599 cites W2137804089 @default.
- W2148607599 cites W2138703558 @default.
- W2148607599 cites W2146743950 @default.
- W2148607599 cites W2150132198 @default.
- W2148607599 cites W2151410031 @default.
- W2148607599 cites W2161750831 @default.
- W2148607599 cites W2162779381 @default.
- W2148607599 cites W2164184330 @default.
- W2148607599 cites W2167303201 @default.
- W2148607599 cites W2167803942 @default.
- W2148607599 cites W2169545266 @default.
- W2148607599 cites W21787296 @default.
- W2148607599 cites W2227417895 @default.