Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148626146> ?p ?o ?g. }
- W2148626146 endingPage "220" @default.
- W2148626146 startingPage "212" @default.
- W2148626146 abstract "Sub-valvular aortic stenosis (SAS) is a common form of left ventricular outflow tract (LVOT) obstruction, which can lead to aortic valve damage. Although surgery for SAS is an accepted treatment, the timing of surgical intervention of SAS remains controversial. This review aims to establish an overview of the natural history and outcome after surgery and factors associated with prognosis in paediatric SAS patients. We searched PubMed and EMBASE for studies that reported factors that negatively affected the prognosis of patients with SAS. Studies were included if they were written in English, published between 1 January 1997 and 31 December 2012 and the mean patient age was <18 years at the time of study entry. Studies were excluded if the study size was <20 patients. A distinction was made between natural history and surgical cohorts. Twenty-four studies were included in this review, encompassing a total of 809 natural history and 1476 surgical patients. Fifty-one percent of natural history patients required surgery. After surgery, there was a substantial reoperation rate. Higher LVOT gradient and the presence of aortic regurgitation (AR) were identified as the foremost independent predictors of a worse outcome. Valve-to-membrane distance was also found to be associated with prognosis, although the results were contradictory. This systematic review underlines the importance of LVOT gradient, aortic valve-to-membrane distance and AR in surgical decision-making in paediatric SAS patients. There is need for collaborative effort to further study the optimal timing of surgery based on LVOT gradient, valve-to-membrane distance and the presence of AR." @default.
- W2148626146 created "2016-06-24" @default.
- W2148626146 creator A5042300012 @default.
- W2148626146 creator A5061259853 @default.
- W2148626146 creator A5080670496 @default.
- W2148626146 creator A5081857846 @default.
- W2148626146 creator A5088415063 @default.
- W2148626146 date "2014-11-05" @default.
- W2148626146 modified "2023-10-10" @default.
- W2148626146 title "Paediatric subvalvular aortic stenosis: a systematic review and meta-analysis of natural history and surgical outcome" @default.
- W2148626146 cites W1644596033 @default.
- W2148626146 cites W1970589587 @default.
- W2148626146 cites W1975210751 @default.
- W2148626146 cites W1996115881 @default.
- W2148626146 cites W1997892354 @default.
- W2148626146 cites W2003660442 @default.
- W2148626146 cites W2020785130 @default.
- W2148626146 cites W2025379709 @default.
- W2148626146 cites W2029900132 @default.
- W2148626146 cites W2033465810 @default.
- W2148626146 cites W2033854597 @default.
- W2148626146 cites W2041478256 @default.
- W2148626146 cites W2044979907 @default.
- W2148626146 cites W2050457367 @default.
- W2148626146 cites W2050848255 @default.
- W2148626146 cites W2051542092 @default.
- W2148626146 cites W2056898608 @default.
- W2148626146 cites W2071148306 @default.
- W2148626146 cites W2071625031 @default.
- W2148626146 cites W2081594713 @default.
- W2148626146 cites W2091652385 @default.
- W2148626146 cites W2095646928 @default.
- W2148626146 cites W2097840408 @default.
- W2148626146 cites W2098763231 @default.
- W2148626146 cites W2111153609 @default.
- W2148626146 cites W2111538796 @default.
- W2148626146 cites W2119354519 @default.
- W2148626146 cites W2122264987 @default.
- W2148626146 cites W2134036852 @default.
- W2148626146 cites W2163122529 @default.
- W2148626146 cites W2163390732 @default.
- W2148626146 cites W2165417199 @default.
- W2148626146 cites W2168924589 @default.
- W2148626146 cites W2169209513 @default.
- W2148626146 cites W4294215472 @default.
- W2148626146 doi "https://doi.org/10.1093/ejcts/ezu423" @default.
- W2148626146 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25378361" @default.
- W2148626146 hasPublicationYear "2014" @default.
- W2148626146 type Work @default.
- W2148626146 sameAs 2148626146 @default.
- W2148626146 citedByCount "18" @default.
- W2148626146 countsByYear W21486261462016 @default.
- W2148626146 countsByYear W21486261462018 @default.
- W2148626146 countsByYear W21486261462019 @default.
- W2148626146 countsByYear W21486261462020 @default.
- W2148626146 countsByYear W21486261462021 @default.
- W2148626146 countsByYear W21486261462022 @default.
- W2148626146 countsByYear W21486261462023 @default.
- W2148626146 crossrefType "journal-article" @default.
- W2148626146 hasAuthorship W2148626146A5042300012 @default.
- W2148626146 hasAuthorship W2148626146A5061259853 @default.
- W2148626146 hasAuthorship W2148626146A5080670496 @default.
- W2148626146 hasAuthorship W2148626146A5081857846 @default.
- W2148626146 hasAuthorship W2148626146A5088415063 @default.
- W2148626146 hasBestOaLocation W21486261461 @default.
- W2148626146 hasConcept C126322002 @default.
- W2148626146 hasConcept C141071460 @default.
- W2148626146 hasConcept C163276114 @default.
- W2148626146 hasConcept C164705383 @default.
- W2148626146 hasConcept C2776570981 @default.
- W2148626146 hasConcept C2777361368 @default.
- W2148626146 hasConcept C2777543888 @default.
- W2148626146 hasConcept C2778789114 @default.
- W2148626146 hasConcept C2780007028 @default.
- W2148626146 hasConcept C2780168065 @default.
- W2148626146 hasConcept C2780225090 @default.
- W2148626146 hasConcept C2780714102 @default.
- W2148626146 hasConcept C71924100 @default.
- W2148626146 hasConceptScore W2148626146C126322002 @default.
- W2148626146 hasConceptScore W2148626146C141071460 @default.
- W2148626146 hasConceptScore W2148626146C163276114 @default.
- W2148626146 hasConceptScore W2148626146C164705383 @default.
- W2148626146 hasConceptScore W2148626146C2776570981 @default.
- W2148626146 hasConceptScore W2148626146C2777361368 @default.
- W2148626146 hasConceptScore W2148626146C2777543888 @default.
- W2148626146 hasConceptScore W2148626146C2778789114 @default.
- W2148626146 hasConceptScore W2148626146C2780007028 @default.
- W2148626146 hasConceptScore W2148626146C2780168065 @default.
- W2148626146 hasConceptScore W2148626146C2780225090 @default.
- W2148626146 hasConceptScore W2148626146C2780714102 @default.
- W2148626146 hasConceptScore W2148626146C71924100 @default.
- W2148626146 hasIssue "2" @default.
- W2148626146 hasLocation W21486261461 @default.
- W2148626146 hasLocation W21486261462 @default.
- W2148626146 hasOpenAccess W2148626146 @default.
- W2148626146 hasPrimaryLocation W21486261461 @default.
- W2148626146 hasRelatedWork W1689122987 @default.
- W2148626146 hasRelatedWork W2053279299 @default.