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• W2148634928 abstract "In contrast to classical chemical phenomenology, theory suggests that proteins may undergo downhill folding without an activation barrier under certain thermodynamic conditions. Recently, the BBL protein was proposed to fold by such a downhill scenario, but discrepancies between experimental results found in different groups argue against this. After briefly reviewing the major experimental studies of the BBL folding mechanism, we show that simulations of both coarse-grained and atomistic models can reconcile the seemingly conflicting observations." @default.
• W2148634928 created "2016-06-24" @default.
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• W2148634928 date "2008-01-08" @default.
• W2148634928 modified "2023-09-27" @default.
• W2148634928 title "Origins of barriers and barrierless folding in BBL" @default.
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• W2148634928 doi "https://doi.org/10.1073/pnas.0709376104" @default.
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