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• W2148682015 abstract "The genetic variances and covariances of traits must be known to predict how they may respond to selection and how covariances among them might affect their evolutionary trajectories. We used the animal model to estimate the genetic variances and covariances of basal metabolic rate (BMR) and maximal metabolic rate (MMR) in a genetically heterogeneous stock of laboratory mice. Narrow-sense heritability ( h 2 ) was approximately 0.38 ± 0.08 for body mass, 0.26 ± 0.08 for whole-animal BMR, 0.24 ± 0.07 for whole-animal MMR, 0.19 ± 0.07 for mass-independent BMR, and 0.16 ± 0.06 for mass-independent MMR. All h 2 estimates were significantly different from zero. The phenotypic correlation of whole animal BMR and MMR was 0.56 ± 0.02, and the corresponding genetic correlation was 0.79 ± 0.12. The phenotypic correlation of mass-independent BMR and MMR was 0.13 ± 0.03, and the corresponding genetic correlation was 0.72 ± 0.03. The genetic correlations of metabolic rates were significantly different from zero, but not significantly different from one. A key assumption of the aerobic capacity model for the evolution of endothermy is that BMR and MMR are linked. The estimated genetic correlation between BMR and MMR is consistent with that assumption, but the genetic correlation is not so high as to preclude independent evolution of BMR and MMR." @default.
• W2148682015 created "2016-06-24" @default.
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• W2148682015 date "2009-08-05" @default.
• W2148682015 modified "2023-10-17" @default.
• W2148682015 title "Genetic variances and covariances of aerobic metabolic rates in laboratory mice" @default.
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• W2148682015 doi "https://doi.org/10.1098/rspb.2009.0980" @default.
• W2148682015 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2817310" @default.
• W2148682015 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19656796" @default.
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