FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148688897> ?p ?o ?g. }

• W2148688897 endingPage "2588" @default.
• W2148688897 startingPage "2582" @default.
• W2148688897 abstract "Anthocyanins are reported to have many health promoting properties; however, despite numerous reports of their bioactivities, their absorption and metabolism in humans are poorly understood. The objective of this research was to detail the pharmacokinetic parameters of anthocyanins after the administration of a 721-mg oral dose of cyanidin 3-glycosides from chokeberry extract to human subjects. Solid-phase extraction, preparative-HPLC, preparative-TLC, HPLC-diode array detection, HPLC-MS, and NMR were utilized to isolate, identity, and quantify anthocyanins in 0- to 7-h (0, 1, 2, 3, 4, 5, 6, 7 h) serum and 0- to 24-h urine samples (total individual urine voids over 24 h). The cumulative concentration of total anthocyanins (parent and metabolites) detected in the serum (0-7 h) was 376.65 +/- 16.20 (nmol x h)/L (area under the concentration time curve), reaching a maximum concentration (C(max) = 96.08 +/- 6.04 nmol/L) within 2.8 h. The parent anthocyanins represented only 32.0% [120.63 +/- 2.85 (nmol x h)/L] of the total anthocyanins detected with 68.0% [256.02 +/- 5.23 (nmol x h) identified as conjugated metabolites. Additionally, the total urinary excretion of anthocyanins over 24 h was 1071.54 +/- 375.46 microg, reaching a maximal rate of excretion (R(max) = 202.74 +/- 85.06 microg/h) at 3.72 +/- 0.83 h. Parallel to the serum data, only 32.5% (347.85 +/- 60.61 microg) of the anthocyanins excreted in the urine (total 24 h) were the parent compounds with 67.5% (723.69 +/- 92.59 microg) occurring as conjugated metabolites. The metabolites were identified as glucuronidated and methylated derivatives of the parent cyanidin 3-glycosides. The above results indicate that cyanidin 3-glycosides are rapidly absorbed and metabolized extensively following a moderate-to-high oral dose in humans." @default.
• W2148688897 created "2016-06-24" @default.
• W2148688897 creator A5037730464 @default.
• W2148688897 creator A5063430213 @default.
• W2148688897 creator A5077067230 @default.
• W2148688897 date "2005-11-01" @default.
• W2148688897 modified "2023-10-16" @default.
• W2148688897 title "Anthocyanins Exist in the Circulation Primarily as Metabolites in Adult Men" @default.
• W2148688897 cites W1900499697 @default.
• W2148688897 cites W1918965474 @default.
• W2148688897 cites W1936440928 @default.
• W2148688897 cites W1948827876 @default.
• W2148688897 cites W1968829227 @default.
• W2148688897 cites W1968985568 @default.
• W2148688897 cites W1971171764 @default.
• W2148688897 cites W1975202491 @default.
• W2148688897 cites W1981145469 @default.
• W2148688897 cites W1986527680 @default.
• W2148688897 cites W1993464664 @default.
• W2148688897 cites W2006949479 @default.
• W2148688897 cites W2016299197 @default.
• W2148688897 cites W2021171647 @default.
• W2148688897 cites W2032115282 @default.
• W2148688897 cites W2052620716 @default.
• W2148688897 cites W2062904391 @default.
• W2148688897 cites W2063765017 @default.
• W2148688897 cites W2115984051 @default.
• W2148688897 cites W2118756389 @default.
• W2148688897 cites W2141832633 @default.
• W2148688897 cites W2147905503 @default.
• W2148688897 cites W2240428226 @default.
• W2148688897 doi "https://doi.org/10.1093/jn/135.11.2582" @default.
• W2148688897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16251615" @default.
• W2148688897 hasPublicationYear "2005" @default.
• W2148688897 type Work @default.
• W2148688897 sameAs 2148688897 @default.
• W2148688897 citedByCount "194" @default.
• W2148688897 countsByYear W21486888972012 @default.
• W2148688897 countsByYear W21486888972013 @default.
• W2148688897 countsByYear W21486888972014 @default.
• W2148688897 countsByYear W21486888972015 @default.
• W2148688897 countsByYear W21486888972016 @default.
• W2148688897 countsByYear W21486888972017 @default.
• W2148688897 countsByYear W21486888972018 @default.
• W2148688897 countsByYear W21486888972019 @default.
• W2148688897 countsByYear W21486888972020 @default.
• W2148688897 countsByYear W21486888972021 @default.
• W2148688897 countsByYear W21486888972022 @default.
• W2148688897 countsByYear W21486888972023 @default.
• W2148688897 crossrefType "journal-article" @default.
• W2148688897 hasAuthorship W2148688897A5037730464 @default.
• W2148688897 hasAuthorship W2148688897A5063430213 @default.
• W2148688897 hasAuthorship W2148688897A5077067230 @default.
• W2148688897 hasBestOaLocation W21486888971 @default.
• W2148688897 hasConcept C10146269 @default.
• W2148688897 hasConcept C112705442 @default.
• W2148688897 hasConcept C179998833 @default.
• W2148688897 hasConcept C185592680 @default.
• W2148688897 hasConcept C194671627 @default.
• W2148688897 hasConcept C2777667348 @default.
• W2148688897 hasConcept C2778945092 @default.
• W2148688897 hasConcept C2780026642 @default.
• W2148688897 hasConcept C31903555 @default.
• W2148688897 hasConcept C43617362 @default.
• W2148688897 hasConcept C55493867 @default.
• W2148688897 hasConcept C62231903 @default.
• W2148688897 hasConcept C71240020 @default.
• W2148688897 hasConcept C71924100 @default.
• W2148688897 hasConcept C81426234 @default.
• W2148688897 hasConcept C98274493 @default.
• W2148688897 hasConceptScore W2148688897C10146269 @default.
• W2148688897 hasConceptScore W2148688897C112705442 @default.
• W2148688897 hasConceptScore W2148688897C179998833 @default.
• W2148688897 hasConceptScore W2148688897C185592680 @default.
• W2148688897 hasConceptScore W2148688897C194671627 @default.
• W2148688897 hasConceptScore W2148688897C2777667348 @default.
• W2148688897 hasConceptScore W2148688897C2778945092 @default.
• W2148688897 hasConceptScore W2148688897C2780026642 @default.
• W2148688897 hasConceptScore W2148688897C31903555 @default.
• W2148688897 hasConceptScore W2148688897C43617362 @default.
• W2148688897 hasConceptScore W2148688897C55493867 @default.
• W2148688897 hasConceptScore W2148688897C62231903 @default.
• W2148688897 hasConceptScore W2148688897C71240020 @default.
• W2148688897 hasConceptScore W2148688897C71924100 @default.
• W2148688897 hasConceptScore W2148688897C81426234 @default.
• W2148688897 hasConceptScore W2148688897C98274493 @default.
• W2148688897 hasIssue "11" @default.
• W2148688897 hasLocation W21486888971 @default.
• W2148688897 hasLocation W21486888972 @default.
• W2148688897 hasOpenAccess W2148688897 @default.
• W2148688897 hasPrimaryLocation W21486888971 @default.
• W2148688897 hasRelatedWork W1979301814 @default.
• W2148688897 hasRelatedWork W1990402960 @default.
• W2148688897 hasRelatedWork W2005097882 @default.
• W2148688897 hasRelatedWork W2008727242 @default.
• W2148688897 hasRelatedWork W2012905376 @default.
• W2148688897 hasRelatedWork W2029670251 @default.
• W2148688897 hasRelatedWork W2412066373 @default.

• next