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- W2148719488 abstract "The direct synthesis of the title amino acid derivatives from carboxylic esters and nitrones can be achieved in fair to good yields when lithium or magnesium ester enolates were treated with nitrones in THF at -78 °C or in Et2O at -20 to 0 °C, respectively. The products from the reaction of t-butyl acetate with 3,4-dihydroisoquinoline N-oxide or 5,5-dimethylpyrroline 1-oxide were transformed into (1,2,3,4-tetrahydroisoquinolin-1-ylidene)acetate or (pyrrolidin-2-ylidene)acetate derivatives in the presence of triphenylphosphine, carbon tetrachloride, and triethylamine in refluxing dichloromethane." @default.
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- W2148719488 date "2001-04-10" @default.
- W2148719488 modified "2023-09-24" @default.
- W2148719488 title "ChemInform Abstract: Direct Synthesis of N-Hydroxy β-Amino Acid Esters from Carboxylic Esters and Nitrones." @default.
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- W2148719488 doi "https://doi.org/10.1002/chin.200115190" @default.
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