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• W2148764576 abstract "We present a generally applicable method allowing rapid identification of causal alleles in mutagenized genomes by next-generation sequencing. Currently used approaches rely on recovering homozygotes or extensive backcrossing. In contrast, SNP-ratio mapping allows rapid cloning of lethal and/or poorly transmitted mutations and second-site modifiers, which are often in complex genetic/transgenic backgrounds." @default.
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• W2148764576 date "2012-08-01" @default.
• W2148764576 modified "2023-10-06" @default.
• W2148764576 title "SNP-Ratio Mapping (SRM): Identifying Lethal Alleles and Mutations in Complex Genetic Backgrounds by Next-Generation Sequencing" @default.
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• W2148764576 doi "https://doi.org/10.1534/genetics.112.141341" @default.
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