FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148833567> ?p ?o ?g. }

• W2148833567 abstract "Chromothripsis is a recently recognized mode of genetic instability that generates chromosomes with strikingly large numbers of segmental re-arrangements. While the characterization of these derivative chromosomes has provided new insights into the processes by which cancer genomes can evolve, the underlying signaling events and molecular mechanisms remain unknown. In medulloblastomas, chromothripsis has been observed to occur in the context of mutational inactivation of p53 and activation of the canonical Hedgehog (Hh) pathway. Recent studies have illuminated mechanistic links between these 2 signaling pathways, including a novel PTCH1 homolog that is regulated by p53. Here, we integrate this new pathway into a hypothetical model for the catastrophic DNA breakage that appears to trigger profound chromosomal rearrangements." @default.
• W2148833567 created "2016-06-24" @default.
• W2148833567 creator A5007286578 @default.
• W2148833567 creator A5089509820 @default.
• W2148833567 date "2015-08-20" @default.
• W2148833567 modified "2023-10-03" @default.
• W2148833567 title "Pathways to chromothripsis" @default.
• W2148833567 cites W1572433661 @default.
• W2148833567 cites W1969665013 @default.
• W2148833567 cites W1983341583 @default.
• W2148833567 cites W2009392284 @default.
• W2148833567 cites W2013000007 @default.
• W2148833567 cites W2015061258 @default.
• W2148833567 cites W2015236057 @default.
• W2148833567 cites W2017168705 @default.
• W2148833567 cites W2018835039 @default.
• W2148833567 cites W2023384448 @default.
• W2148833567 cites W2041880423 @default.
• W2148833567 cites W2044315923 @default.
• W2148833567 cites W2044433401 @default.
• W2148833567 cites W2047680962 @default.
• W2148833567 cites W2049342310 @default.
• W2148833567 cites W2073571647 @default.
• W2148833567 cites W2078151888 @default.
• W2148833567 cites W2086202912 @default.
• W2148833567 cites W2087001239 @default.
• W2148833567 cites W2102618729 @default.
• W2148833567 cites W2108339331 @default.
• W2148833567 cites W2109948920 @default.
• W2148833567 cites W2116964110 @default.
• W2148833567 cites W2118966275 @default.
• W2148833567 cites W2123491442 @default.
• W2148833567 cites W2131075994 @default.
• W2148833567 cites W2154141161 @default.
• W2148833567 cites W2160538256 @default.
• W2148833567 cites W2165664339 @default.
• W2148833567 cites W2167532631 @default.
• W2148833567 cites W2335127095 @default.
• W2148833567 doi "https://doi.org/10.1080/15384101.2015.1068483" @default.
• W2148833567 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4825555" @default.
• W2148833567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26178348" @default.
• W2148833567 hasPublicationYear "2015" @default.
• W2148833567 type Work @default.
• W2148833567 sameAs 2148833567 @default.
• W2148833567 citedByCount "12" @default.
• W2148833567 countsByYear W21488335672016 @default.
• W2148833567 countsByYear W21488335672017 @default.
• W2148833567 countsByYear W21488335672018 @default.
• W2148833567 countsByYear W21488335672019 @default.
• W2148833567 countsByYear W21488335672020 @default.
• W2148833567 countsByYear W21488335672021 @default.
• W2148833567 crossrefType "journal-article" @default.
• W2148833567 hasAuthorship W2148833567A5007286578 @default.
• W2148833567 hasAuthorship W2148833567A5089509820 @default.
• W2148833567 hasBestOaLocation W21488335671 @default.
• W2148833567 hasConcept C104317684 @default.
• W2148833567 hasConcept C140752955 @default.
• W2148833567 hasConcept C143425029 @default.
• W2148833567 hasConcept C151730666 @default.
• W2148833567 hasConcept C178169997 @default.
• W2148833567 hasConcept C2779343474 @default.
• W2148833567 hasConcept C30481170 @default.
• W2148833567 hasConcept C54355233 @default.
• W2148833567 hasConcept C552990157 @default.
• W2148833567 hasConcept C62478195 @default.
• W2148833567 hasConcept C70721500 @default.
• W2148833567 hasConcept C86803240 @default.
• W2148833567 hasConcept C88498014 @default.
• W2148833567 hasConcept C95444343 @default.
• W2148833567 hasConcept C99983632 @default.
• W2148833567 hasConceptScore W2148833567C104317684 @default.
• W2148833567 hasConceptScore W2148833567C140752955 @default.
• W2148833567 hasConceptScore W2148833567C143425029 @default.
• W2148833567 hasConceptScore W2148833567C151730666 @default.
• W2148833567 hasConceptScore W2148833567C178169997 @default.
• W2148833567 hasConceptScore W2148833567C2779343474 @default.
• W2148833567 hasConceptScore W2148833567C30481170 @default.
• W2148833567 hasConceptScore W2148833567C54355233 @default.
• W2148833567 hasConceptScore W2148833567C552990157 @default.
• W2148833567 hasConceptScore W2148833567C62478195 @default.
• W2148833567 hasConceptScore W2148833567C70721500 @default.
• W2148833567 hasConceptScore W2148833567C86803240 @default.
• W2148833567 hasConceptScore W2148833567C88498014 @default.
• W2148833567 hasConceptScore W2148833567C95444343 @default.
• W2148833567 hasConceptScore W2148833567C99983632 @default.
• W2148833567 hasLocation W21488335671 @default.
• W2148833567 hasLocation W21488335672 @default.
• W2148833567 hasLocation W21488335673 @default.
• W2148833567 hasLocation W21488335674 @default.
• W2148833567 hasOpenAccess W2148833567 @default.
• W2148833567 hasPrimaryLocation W21488335671 @default.
• W2148833567 hasRelatedWork W1505909540 @default.
• W2148833567 hasRelatedWork W1601755300 @default.
• W2148833567 hasRelatedWork W1969665013 @default.
• W2148833567 hasRelatedWork W2045762186 @default.
• W2148833567 hasRelatedWork W2069098370 @default.
• W2148833567 hasRelatedWork W2095617425 @default.
• W2148833567 hasRelatedWork W2098152017 @default.
• W2148833567 hasRelatedWork W2109948920 @default.
• W2148833567 hasRelatedWork W2150194381 @default.

• next