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- W2148972318 abstract "A highly enantioselective aldol reaction of acetaldehyde and a wide scope of isatins has been presented only using readily available 4-hydroxydiarylprolinol as catalyst, affording various desired 3-substituted 3-hydroxyindolin-2-one adducts with moderate to high yield (up to 95%) and good enantioselectivities (up to 98% ee). This method not only represents an example of concise stereoselective synthesis of enantiopure (R)-convolutamydines B and E, but also firstly exhibits expedient asymmetric synthesis optically active (−)-donaxaridine and (R)-chimonamidine." @default.
- W2148972318 created "2016-06-24" @default.
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- W2148972318 date "2010-02-01" @default.
- W2148972318 modified "2023-10-18" @default.
- W2148972318 title "Highly enantioselective aldol reaction of acetaldehyde and isatins only with 4-hydroxydiarylprolinol as catalyst: concise stereoselective synthesis of (R)-convolutamydines B and E, (−)-donaxaridine and (R)-chimonamidine" @default.
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- W2148972318 doi "https://doi.org/10.1016/j.tet.2009.12.041" @default.
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