Matches in SemOpenAlex for { <https://semopenalex.org/work/W2148989073> ?p ?o ?g. }
- W2148989073 endingPage "98" @default.
- W2148989073 startingPage "83" @default.
- W2148989073 abstract "Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis and essential to maintain the continuous production of spermatozoa after the onset of puberty in the male. The study of the male germ line is important for understanding the process of spermatogenesis, unravelling mechanisms of stemness maintenance, cell differentiation, and cell-to-cell interactions. The transplantation of SSCs can contribute to the preservation of the genome of valuable individuals in assisted reproduction programs. In addition to the importance of SSCs for male fertility, their study has recently stimulated interest in the generation of genetically modified animals because manipulations of the male germ line at the SSC stage will be maintained in the long term and transmitted to the offspring. Studies performed mainly in the mouse model have laid the groundwork for facilitating advancements in the field of male germ line biology, but more progress is needed in nonrodent species in order to translate the technology to the agricultural and biomedical fields. The lack of reliable markers for isolating germ cells from testicular somatic cells and the lack of knowledge of the requirements for germ cell maintenance have precluded their long-term maintenance in domestic animals. Nevertheless, some progress has been made. In this review, we will focus on the state of the art in the isolation, characterization, culture, and manipulation of SSCs and the use of germ cell transplantation in domestic animals." @default.
- W2148989073 created "2016-06-24" @default.
- W2148989073 creator A5009143826 @default.
- W2148989073 creator A5061235320 @default.
- W2148989073 date "2015-05-19" @default.
- W2148989073 modified "2023-09-30" @default.
- W2148989073 title "Beyond the Mouse Monopoly: Studying the Male Germ Line in Domestic Animal Models" @default.
- W2148989073 cites W1505671001 @default.
- W2148989073 cites W1530276093 @default.
- W2148989073 cites W1582722466 @default.
- W2148989073 cites W1668126494 @default.
- W2148989073 cites W1820910203 @default.
- W2148989073 cites W1832500487 @default.
- W2148989073 cites W1893831771 @default.
- W2148989073 cites W1919819691 @default.
- W2148989073 cites W1963910681 @default.
- W2148989073 cites W1964699298 @default.
- W2148989073 cites W1965959993 @default.
- W2148989073 cites W1970448922 @default.
- W2148989073 cites W1970574041 @default.
- W2148989073 cites W1974157202 @default.
- W2148989073 cites W1976067201 @default.
- W2148989073 cites W1976102588 @default.
- W2148989073 cites W1976508887 @default.
- W2148989073 cites W1977825177 @default.
- W2148989073 cites W1977846682 @default.
- W2148989073 cites W1978397931 @default.
- W2148989073 cites W1980440773 @default.
- W2148989073 cites W1982756787 @default.
- W2148989073 cites W1983892940 @default.
- W2148989073 cites W1989644493 @default.
- W2148989073 cites W1989958081 @default.
- W2148989073 cites W1990205198 @default.
- W2148989073 cites W1990406664 @default.
- W2148989073 cites W1991417722 @default.
- W2148989073 cites W1995096578 @default.
- W2148989073 cites W1995321595 @default.
- W2148989073 cites W1995869647 @default.
- W2148989073 cites W1997108574 @default.
- W2148989073 cites W1999681243 @default.
- W2148989073 cites W2001812565 @default.
- W2148989073 cites W2002120333 @default.
- W2148989073 cites W2003280782 @default.
- W2148989073 cites W2004352384 @default.
- W2148989073 cites W2009024144 @default.
- W2148989073 cites W2009778512 @default.
- W2148989073 cites W2009932279 @default.
- W2148989073 cites W2012457295 @default.
- W2148989073 cites W2013253333 @default.
- W2148989073 cites W2013470002 @default.
- W2148989073 cites W2016789158 @default.
- W2148989073 cites W2016979788 @default.
- W2148989073 cites W2021730536 @default.
- W2148989073 cites W2021887764 @default.
- W2148989073 cites W2021971921 @default.
- W2148989073 cites W2024174661 @default.
- W2148989073 cites W2026286888 @default.
- W2148989073 cites W2026475860 @default.
- W2148989073 cites W2029775528 @default.
- W2148989073 cites W2031616319 @default.
- W2148989073 cites W2032486885 @default.
- W2148989073 cites W2033767465 @default.
- W2148989073 cites W2034488904 @default.
- W2148989073 cites W203515890 @default.
- W2148989073 cites W2036324729 @default.
- W2148989073 cites W2036363447 @default.
- W2148989073 cites W2043621728 @default.
- W2148989073 cites W2045519522 @default.
- W2148989073 cites W2046441178 @default.
- W2148989073 cites W2048329493 @default.
- W2148989073 cites W2049621829 @default.
- W2148989073 cites W2050887341 @default.
- W2148989073 cites W2051957261 @default.
- W2148989073 cites W2054743870 @default.
- W2148989073 cites W2056708915 @default.
- W2148989073 cites W2056849756 @default.
- W2148989073 cites W2059126165 @default.
- W2148989073 cites W2060180820 @default.
- W2148989073 cites W2060932360 @default.
- W2148989073 cites W2061184966 @default.
- W2148989073 cites W2062116038 @default.
- W2148989073 cites W2062448341 @default.
- W2148989073 cites W2066859997 @default.
- W2148989073 cites W2069061113 @default.
- W2148989073 cites W2070861068 @default.
- W2148989073 cites W2071496358 @default.
- W2148989073 cites W2073358461 @default.
- W2148989073 cites W2073738799 @default.
- W2148989073 cites W2076676430 @default.
- W2148989073 cites W2077915031 @default.
- W2148989073 cites W2080195551 @default.
- W2148989073 cites W2081023675 @default.
- W2148989073 cites W2084591699 @default.
- W2148989073 cites W2086183863 @default.
- W2148989073 cites W2087776075 @default.
- W2148989073 cites W2088424258 @default.
- W2148989073 cites W2089173926 @default.
- W2148989073 cites W2089902726 @default.