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- W2149061610 abstract "A 27-year-old woman with anorexia nervosa took 60 tablets of Slow-K (sustained release potassium chloride 600 mg; 8 mmol each of K+ and Cl -) and soon started to vomit. Her potassium supplement therapy had been discontinued one week prior to admission when the plasma potassium concentration was 3 9 mmol/litre. Twelve hours after the ingestion she was cyanosed with cold extremities, poor peripheral pulses, a regular pulse of 70/min and blood pressure 100/60 mmHg. The electrocardiogram showed first degree heart block, wide QRS complexes and tall T waves (Fig. 1). The plasma potassium concentration was 9 1 mmol/litre and urea concentration 3-4 mmol/ litre. Blood gas analysis revealed a mixed metabolic and respiratory acidosis; H+ 58 nmol/litre, PCO2 4-6 kPa, HCO3 14-8 mmol/litre and P02 6-8 kPa. She was given oxygen and 30 g calcium polystyrene sulphonate (calcium resonium) orally. Twenty ml 10% calcium gluconate and 50 ml 50% dextrose with 10 units soluble insulin were administered intravenously; 100 ml 8-4% sodium bicarbonate were given to correct the metabolic component of the acidosis. Within 1-2 minutes of giving calcium gluconate, the QRS complexes on the electrocardiogram reverted to normal and the PR interval shortened (Fig. 1). Repeat blood gas analysis 30 minutes following admission revealed H+ 50 nmol/litre, PCO2 5 0 kPa, HCO3 18 5 nmol/litre and P02 12-7 kPa. Intravenous fluids and frusemide were given to force a diuresis during which the urine output was" @default.
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- W2149061610 date "1988-12-01" @default.
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- W2149061610 title "Poisoning with sustained release potassium." @default.
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- W2149061610 doi "https://doi.org/10.1136/emj.5.4.206" @default.
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