FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149074966> ?p ?o ?g. }

• W2149074966 endingPage "7060" @default.
• W2149074966 startingPage "7053" @default.
• W2149074966 abstract "Abstract Pseudoalteromonas haloplanktis TAB 23 is a Gram‐negative psychrophilic bacterium isolated from the Antarctic coastal sea. To survive in these conditions psychrophilic bacteria have evolved typical membrane lipids and “antifreeze” proteins to protect the inner side of the microorganism. As for Gram‐negative bacteria, the outer membrane is mainly constituted by lipopoly‐ or lipooligosaccharides (LPS or LOS, respectively), which lean towards the external environment. Despite this, very little is known about the peculiarity of LPS from Gram‐negative psychrophilic bacteria and what their role is in adaptation to cold temperature. Here we report the complete structure of the LOS from P. haloplanktis TAB 23. The lipid A was characterized by MALDI‐TOF MS analysis and was tested in vitro showing a significant inhibitory effect on the LPS‐induced pro‐inflammatory cytokine production when added in culture with LPS from Escherichia coli . The product obtained after de‐O‐acylation of the LPS was analyzed by MALDI‐TOF MS revealing the presence of several molecular species, differing in phosphorylation degree and oligosaccharide length. The oligosaccharide portion released after strong alkaline hydrolysis was purified by anion‐exchange chromatography–pulsed amperometric detection (HPAEC‐PAD) to give three main fractions, characterized by means of 2D NMR spectroscopy, which showed a very short highly phosphorylated saccharidic chain with the following general structure. α‐Hep p 3R,6R,4R′‐(1→5)‐α‐Kdo p4P ‐(2→6)‐β‐Glc p N4R‐(1→6)‐α‐Glc p N 1P (R=H 2 PO 3 or H; R′=α‐Gal p ‐(1→4)‐β‐Gal p ‐(1→ or H)." @default.
• W2149074966 created "2016-06-24" @default.
• W2149074966 creator A5011970616 @default.
• W2149074966 creator A5019938964 @default.
• W2149074966 creator A5032641933 @default.
• W2149074966 creator A5046090387 @default.
• W2149074966 creator A5048966484 @default.
• W2149074966 creator A5053320934 @default.
• W2149074966 creator A5054577883 @default.
• W2149074966 creator A5054749081 @default.
• W2149074966 date "2011-05-09" @default.
• W2149074966 modified "2023-10-18" @default.
• W2149074966 title "Structural Investigation and Biological Activity of the Lipooligosaccharide from the Psychrophilic Bacterium Pseudoalteromonas haloplanktis TAB 23" @default.
• W2149074966 cites W1523758704 @default.
• W2149074966 cites W1593561740 @default.
• W2149074966 cites W163485404 @default.
• W2149074966 cites W166706415 @default.
• W2149074966 cites W1753217596 @default.
• W2149074966 cites W1927751033 @default.
• W2149074966 cites W1929084397 @default.
• W2149074966 cites W1978290603 @default.
• W2149074966 cites W1997902049 @default.
• W2149074966 cites W2002439671 @default.
• W2149074966 cites W2002559694 @default.
• W2149074966 cites W2007390507 @default.
• W2149074966 cites W2010683661 @default.
• W2149074966 cites W2011683499 @default.
• W2149074966 cites W2012313889 @default.
• W2149074966 cites W2014211280 @default.
• W2149074966 cites W2019636412 @default.
• W2149074966 cites W2020925800 @default.
• W2149074966 cites W2024119672 @default.
• W2149074966 cites W2049151620 @default.
• W2149074966 cites W2054766392 @default.
• W2149074966 cites W2057007315 @default.
• W2149074966 cites W2057287956 @default.
• W2149074966 cites W2062835892 @default.
• W2149074966 cites W2075540648 @default.
• W2149074966 cites W2083118614 @default.
• W2149074966 cites W2084040948 @default.
• W2149074966 cites W2084053592 @default.
• W2149074966 cites W2087886577 @default.
• W2149074966 cites W2091447158 @default.
• W2149074966 cites W2092258627 @default.
• W2149074966 cites W2101303284 @default.
• W2149074966 cites W2106305746 @default.
• W2149074966 cites W2108948932 @default.
• W2149074966 cites W2128469341 @default.
• W2149074966 cites W2136540250 @default.
• W2149074966 cites W2137659876 @default.
• W2149074966 cites W2146867625 @default.
• W2149074966 cites W2146948320 @default.
• W2149074966 cites W968790055 @default.
• W2149074966 doi "https://doi.org/10.1002/chem.201100579" @default.
• W2149074966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21557359" @default.
• W2149074966 hasPublicationYear "2011" @default.
• W2149074966 type Work @default.
• W2149074966 sameAs 2149074966 @default.
• W2149074966 citedByCount "31" @default.
• W2149074966 countsByYear W21490749662012 @default.
• W2149074966 countsByYear W21490749662013 @default.
• W2149074966 countsByYear W21490749662014 @default.
• W2149074966 countsByYear W21490749662015 @default.
• W2149074966 countsByYear W21490749662016 @default.
• W2149074966 countsByYear W21490749662017 @default.
• W2149074966 countsByYear W21490749662018 @default.
• W2149074966 countsByYear W21490749662019 @default.
• W2149074966 countsByYear W21490749662020 @default.
• W2149074966 countsByYear W21490749662021 @default.
• W2149074966 countsByYear W21490749662022 @default.
• W2149074966 countsByYear W21490749662023 @default.
• W2149074966 crossrefType "journal-article" @default.
• W2149074966 hasAuthorship W2149074966A5011970616 @default.
• W2149074966 hasAuthorship W2149074966A5019938964 @default.
• W2149074966 hasAuthorship W2149074966A5032641933 @default.
• W2149074966 hasAuthorship W2149074966A5046090387 @default.
• W2149074966 hasAuthorship W2149074966A5048966484 @default.
• W2149074966 hasAuthorship W2149074966A5053320934 @default.
• W2149074966 hasAuthorship W2149074966A5054577883 @default.
• W2149074966 hasAuthorship W2149074966A5054749081 @default.
• W2149074966 hasConcept C104317684 @default.
• W2149074966 hasConcept C134018914 @default.
• W2149074966 hasConcept C144464004 @default.
• W2149074966 hasConcept C146587185 @default.
• W2149074966 hasConcept C181199279 @default.
• W2149074966 hasConcept C185592680 @default.
• W2149074966 hasConcept C22802001 @default.
• W2149074966 hasConcept C2778754761 @default.
• W2149074966 hasConcept C523546767 @default.
• W2149074966 hasConcept C54355233 @default.
• W2149074966 hasConcept C547475151 @default.
• W2149074966 hasConcept C55493867 @default.
• W2149074966 hasConcept C86803240 @default.
• W2149074966 hasConcept C89423630 @default.
• W2149074966 hasConceptScore W2149074966C104317684 @default.
• W2149074966 hasConceptScore W2149074966C134018914 @default.
• W2149074966 hasConceptScore W2149074966C144464004 @default.
• W2149074966 hasConceptScore W2149074966C146587185 @default.

• next