Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149105261> ?p ?o ?g. }
- W2149105261 endingPage "2133" @default.
- W2149105261 startingPage "2125" @default.
- W2149105261 abstract "Abstract IL-12 is such a pivotal cytokine that it has been called the third signal for T cell activation, TCR engagement being the first and costimulation being the second. It has been generally viewed that the resident CD8+ dendritic cell (DC) subset is the predominant IL-12–producing cell type. In this study, we found, although this is so under steady state conditions, under inflammatory conditions monocyte-derived DC (mDC) became a major cell type producing IL-12. Depletion of either type of DC resulted in reduced production of IL-12 in vivo. For CD8+ DC, IL-12 production could be stimulated by various pathways viz. signaling through MyD88, Trif, or nucleotide-binding oligomerization domain (Nod)-like receptors. In contrast, for mDC, IL-12 production was mainly dependent on MyD88 signaling. Thus, conventional DCs and mDCs use different pathways to regulate IL-12 production." @default.
- W2149105261 created "2016-06-24" @default.
- W2149105261 creator A5029800824 @default.
- W2149105261 creator A5039875937 @default.
- W2149105261 creator A5043091521 @default.
- W2149105261 creator A5066921033 @default.
- W2149105261 creator A5076399455 @default.
- W2149105261 creator A5083195546 @default.
- W2149105261 creator A5085680061 @default.
- W2149105261 creator A5089160734 @default.
- W2149105261 creator A5089975854 @default.
- W2149105261 creator A5090743958 @default.
- W2149105261 date "2010-08-15" @default.
- W2149105261 modified "2023-10-07" @default.
- W2149105261 title "Resident and Monocyte-Derived Dendritic Cells Become Dominant IL-12 Producers under Different Conditions and Signaling Pathways" @default.
- W2149105261 cites W1492418658 @default.
- W2149105261 cites W1646363625 @default.
- W2149105261 cites W1689372518 @default.
- W2149105261 cites W1906900122 @default.
- W2149105261 cites W1935913665 @default.
- W2149105261 cites W1969975290 @default.
- W2149105261 cites W1976851579 @default.
- W2149105261 cites W1977142289 @default.
- W2149105261 cites W1981087308 @default.
- W2149105261 cites W1981718801 @default.
- W2149105261 cites W1987481383 @default.
- W2149105261 cites W1990083653 @default.
- W2149105261 cites W1992439632 @default.
- W2149105261 cites W1995744610 @default.
- W2149105261 cites W1997951134 @default.
- W2149105261 cites W1998844140 @default.
- W2149105261 cites W2000952771 @default.
- W2149105261 cites W2009219530 @default.
- W2149105261 cites W2030745929 @default.
- W2149105261 cites W2051927549 @default.
- W2149105261 cites W2067677689 @default.
- W2149105261 cites W2073541049 @default.
- W2149105261 cites W2077084122 @default.
- W2149105261 cites W2095881540 @default.
- W2149105261 cites W2100313593 @default.
- W2149105261 cites W2103748070 @default.
- W2149105261 cites W2104904748 @default.
- W2149105261 cites W2104910525 @default.
- W2149105261 cites W2108765339 @default.
- W2149105261 cites W2117985944 @default.
- W2149105261 cites W2125600524 @default.
- W2149105261 cites W2126735123 @default.
- W2149105261 cites W2128287837 @default.
- W2149105261 cites W2133266616 @default.
- W2149105261 cites W2136786880 @default.
- W2149105261 cites W2141120240 @default.
- W2149105261 cites W2151369808 @default.
- W2149105261 cites W2159470225 @default.
- W2149105261 cites W2169539795 @default.
- W2149105261 cites W2258289510 @default.
- W2149105261 cites W2466626717 @default.
- W2149105261 cites W4313333789 @default.
- W2149105261 cites W78744612 @default.
- W2149105261 doi "https://doi.org/10.4049/jimmunol.0903793" @default.
- W2149105261 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20644172" @default.
- W2149105261 hasPublicationYear "2010" @default.
- W2149105261 type Work @default.
- W2149105261 sameAs 2149105261 @default.
- W2149105261 citedByCount "43" @default.
- W2149105261 countsByYear W21491052612012 @default.
- W2149105261 countsByYear W21491052612013 @default.
- W2149105261 countsByYear W21491052612014 @default.
- W2149105261 countsByYear W21491052612015 @default.
- W2149105261 countsByYear W21491052612016 @default.
- W2149105261 countsByYear W21491052612017 @default.
- W2149105261 countsByYear W21491052612018 @default.
- W2149105261 countsByYear W21491052612019 @default.
- W2149105261 countsByYear W21491052612020 @default.
- W2149105261 countsByYear W21491052612021 @default.
- W2149105261 countsByYear W21491052612022 @default.
- W2149105261 countsByYear W21491052612023 @default.
- W2149105261 crossrefType "journal-article" @default.
- W2149105261 hasAuthorship W2149105261A5029800824 @default.
- W2149105261 hasAuthorship W2149105261A5039875937 @default.
- W2149105261 hasAuthorship W2149105261A5043091521 @default.
- W2149105261 hasAuthorship W2149105261A5066921033 @default.
- W2149105261 hasAuthorship W2149105261A5076399455 @default.
- W2149105261 hasAuthorship W2149105261A5083195546 @default.
- W2149105261 hasAuthorship W2149105261A5085680061 @default.
- W2149105261 hasAuthorship W2149105261A5089160734 @default.
- W2149105261 hasAuthorship W2149105261A5089975854 @default.
- W2149105261 hasAuthorship W2149105261A5090743958 @default.
- W2149105261 hasBestOaLocation W21491052611 @default.
- W2149105261 hasConcept C136449434 @default.
- W2149105261 hasConcept C167672396 @default.
- W2149105261 hasConcept C170493617 @default.
- W2149105261 hasConcept C185592680 @default.
- W2149105261 hasConcept C19317047 @default.
- W2149105261 hasConcept C203014093 @default.
- W2149105261 hasConcept C2776090121 @default.
- W2149105261 hasConcept C2776709828 @default.
- W2149105261 hasConcept C2778170410 @default.
- W2149105261 hasConcept C2778690821 @default.