FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149115674> ?p ?o ?g. }

• W2149115674 endingPage "1104" @default.
• W2149115674 startingPage "1094" @default.
• W2149115674 abstract "T antigen (Galbeta1-3GalNAcalpha1-Ser/Thr), the well-known tumor-associated antigen, is a core 1 mucin-type O-glycan structure that is synthesized by core 1 beta1,3-galactosyltransferase (C1beta3GalT), which transfers Gal from UDP-Gal to Tn antigen (GalNAcalpha1-Ser/Thr). Three putative C1beta3GalTs have been identified in Drosophila. However, although all three are expressed in embryos, their roles during embryogenesis have not yet been clarified. In this study, we used P-element inserted mutants to show that CG9520, one of the three putative C1beta3GalTs, synthesizes T antigen expressed on the central nervous system (CNS) during embryogenesis. We also found that T antigen was expressed on a subset of the embryonic hemocytes. CG9520 mutant embryos showed the loss of T antigens on the CNS and on a subset of hemocytes. Then, the loss of T antigens was rescued by precise excision of the P-element inserted into the CG9520 gene. Our data demonstrate that T antigens expressed on the CNS and on a subset of hemocytes are synthesized by CG9520 in the Drosophila embryo. In addition, we found that the number of circulating hemocytes was reduced in third instar larvae of CG9520 mutant. We, therefore, named the CG9520 gene Drosophila core 1 beta1,3-galactosyltransferase 1 because it is responsible for the synthesis and function of T antigen in vivo." @default.
• W2149115674 created "2016-06-24" @default.
• W2149115674 creator A5021578125 @default.
• W2149115674 creator A5025429263 @default.
• W2149115674 creator A5030237364 @default.
• W2149115674 creator A5035471264 @default.
• W2149115674 creator A5047636089 @default.
• W2149115674 creator A5053618837 @default.
• W2149115674 creator A5061673601 @default.
• W2149115674 creator A5065566375 @default.
• W2149115674 creator A5085432609 @default.
• W2149115674 date "2008-08-29" @default.
• W2149115674 modified "2023-09-27" @default.
• W2149115674 title "Identification of the Drosophila core 1 1,3-galactosyltransferase gene that synthesizes T antigen in the embryonic central nervous system and hemocytes" @default.
• W2149115674 cites W1505499718 @default.
• W2149115674 cites W1966913492 @default.
• W2149115674 cites W1982650114 @default.
• W2149115674 cites W1984980675 @default.
• W2149115674 cites W1985356079 @default.
• W2149115674 cites W1996070154 @default.
• W2149115674 cites W1997955557 @default.
• W2149115674 cites W1999721821 @default.
• W2149115674 cites W2007372895 @default.
• W2149115674 cites W2007731313 @default.
• W2149115674 cites W2009865010 @default.
• W2149115674 cites W2014677429 @default.
• W2149115674 cites W2019881628 @default.
• W2149115674 cites W2020773645 @default.
• W2149115674 cites W2024115143 @default.
• W2149115674 cites W2030131753 @default.
• W2149115674 cites W2031409384 @default.
• W2149115674 cites W2034108485 @default.
• W2149115674 cites W2036625856 @default.
• W2149115674 cites W2040236732 @default.
• W2149115674 cites W2050803950 @default.
• W2149115674 cites W2051782048 @default.
• W2149115674 cites W2054652369 @default.
• W2149115674 cites W2068627747 @default.
• W2149115674 cites W2069557642 @default.
• W2149115674 cites W2071735046 @default.
• W2149115674 cites W2080656460 @default.
• W2149115674 cites W2080957219 @default.
• W2149115674 cites W2087302864 @default.
• W2149115674 cites W2092239727 @default.
• W2149115674 cites W2114340303 @default.
• W2149115674 cites W2115151917 @default.
• W2149115674 cites W2116497667 @default.
• W2149115674 cites W2128367954 @default.
• W2149115674 cites W2139368593 @default.
• W2149115674 cites W2141932361 @default.
• W2149115674 cites W2144014252 @default.
• W2149115674 cites W2150675831 @default.
• W2149115674 cites W2151927994 @default.
• W2149115674 cites W2152911705 @default.
• W2149115674 cites W2153139888 @default.
• W2149115674 cites W2158117114 @default.
• W2149115674 cites W2159334577 @default.
• W2149115674 cites W2159384610 @default.
• W2149115674 cites W2164001459 @default.
• W2149115674 cites W2308566911 @default.
• W2149115674 cites W4212995480 @default.
• W2149115674 doi "https://doi.org/10.1093/glycob/cwn094" @default.
• W2149115674 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18824562" @default.
• W2149115674 hasPublicationYear "2008" @default.
• W2149115674 type Work @default.
• W2149115674 sameAs 2149115674 @default.
• W2149115674 citedByCount "29" @default.
• W2149115674 countsByYear W21491156742012 @default.
• W2149115674 countsByYear W21491156742013 @default.
• W2149115674 countsByYear W21491156742014 @default.
• W2149115674 countsByYear W21491156742015 @default.
• W2149115674 countsByYear W21491156742016 @default.
• W2149115674 countsByYear W21491156742017 @default.
• W2149115674 countsByYear W21491156742018 @default.
• W2149115674 countsByYear W21491156742019 @default.
• W2149115674 countsByYear W21491156742021 @default.
• W2149115674 countsByYear W21491156742022 @default.
• W2149115674 crossrefType "journal-article" @default.
• W2149115674 hasAuthorship W2149115674A5021578125 @default.
• W2149115674 hasAuthorship W2149115674A5025429263 @default.
• W2149115674 hasAuthorship W2149115674A5030237364 @default.
• W2149115674 hasAuthorship W2149115674A5035471264 @default.
• W2149115674 hasAuthorship W2149115674A5047636089 @default.
• W2149115674 hasAuthorship W2149115674A5053618837 @default.
• W2149115674 hasAuthorship W2149115674A5061673601 @default.
• W2149115674 hasAuthorship W2149115674A5065566375 @default.
• W2149115674 hasAuthorship W2149115674A5085432609 @default.
• W2149115674 hasBestOaLocation W21491156741 @default.
• W2149115674 hasConcept C104317684 @default.
• W2149115674 hasConcept C143065580 @default.
• W2149115674 hasConcept C145103041 @default.
• W2149115674 hasConcept C147483822 @default.
• W2149115674 hasConcept C153911025 @default.
• W2149115674 hasConcept C196843134 @default.
• W2149115674 hasConcept C54355233 @default.
• W2149115674 hasConcept C86803240 @default.
• W2149115674 hasConcept C87073359 @default.
• W2149115674 hasConcept C95444343 @default.

• next