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- W2149142746 abstract "This study investigated the frequency and importance of Ki-ras codon 12 mutations in 99 Hong Kong Chinese colorectal carcinoma specimens by allele-specific oligonucleotide hybridization. The frequency of mutations detected was 30% and the most common mutation observed resulted in aspartic acid substitutions. Previous studies showed that specific Ki-ras mutations have been significantly associated with prognosis. Ki-ras codon 12 point mutational activation in CRC was significantly associated with the differentiation status of tumors in this study. Ethnic differences in the patterns of Ki-ras codon 12 point mutations were observed." @default.
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- W2149142746 date "1998-12-01" @default.
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- W2149142746 title "Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients" @default.
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- W2149142746 doi "https://doi.org/10.1016/s0304-3835(98)00257-2" @default.
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