Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149144611> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2149144611 endingPage "39" @default.
- W2149144611 startingPage "35" @default.
- W2149144611 abstract "Proper evaluation of lung nodules is a difficult issue for clinical management of patients. Discriminating metastatic endometrial stromal sarcoma (ESS) from other primary spindle cell neoplasms of the lung using histological analysis can be challenging. This is particularly true when an adequate clinical history is lacking, because ESS metastasis can be delayed by a couple of decades. To emphasize the importance of the correlation of pathological findings with clinical history and imaging studies, we investigated 11 cases of ESS (seven low grade and four high grade) metastatic to the lung. All cases presented with one to multiple unilateral or bilateral lung nodules that were detected by chest computed tomography. Primary ESS was diagnosed from hysterectomy specimens except for one by endometrial biopsy, 0.5 to 23 years prior to metastasis. Immunohistochemical studies showed that all ESS cases were moderately to strongly positive for Bcl-2 and CD10 with >50% of tumor cells stained, except for one high grade ESS that was negative for CD10. Eight (72.7%) and seven (63.6) of the 11 cases showed positive estrogen and progesterone receptors, respectively, with a majority of positive cases showing diffuse and moderate to strong staining. Strong but patchy staining for CD34 was detected in one (9.1%) case with smooth muscle differentiation. CK7 and TTF-1 were negative in all cases. Two (18.2%) cases exhibited patchy and strong positivity for caldesmon. Two (18.2%) low grade ESS cases showed moderate to strong AE1/AE3 positivity in >50% of tumor cells, one of which also showed moderate CK19 and Cam 5.2 staining in >30% of tumor cells. One should be cautious when assessing spindle cell neoplasms of the lung in women with a history of hysterectomy. Correlation of clinical history and imaging studies with histological and immunohistochemical findings is essential to diagnosis of metastatic ESS to the lung." @default.
- W2149144611 created "2016-06-24" @default.
- W2149144611 creator A5008581924 @default.
- W2149144611 creator A5042723430 @default.
- W2149144611 creator A5049477662 @default.
- W2149144611 creator A5051965167 @default.
- W2149144611 creator A5070525280 @default.
- W2149144611 creator A5074231400 @default.
- W2149144611 creator A5089276174 @default.
- W2149144611 creator A5090428050 @default.
- W2149144611 date "2011-08-15" @default.
- W2149144611 modified "2023-09-27" @default.
- W2149144611 title "Metastatic endometrial stromal sarcoma of the lung: importance of immunohistochemical staining, clinical history and imaging studies" @default.
- W2149144611 cites W1577320559 @default.
- W2149144611 cites W1993087863 @default.
- W2149144611 cites W2004304259 @default.
- W2149144611 cites W2041907050 @default.
- W2149144611 cites W2043679774 @default.
- W2149144611 cites W2046352139 @default.
- W2149144611 cites W2053237722 @default.
- W2149144611 cites W2058778654 @default.
- W2149144611 cites W2094818926 @default.
- W2149144611 cites W2129654603 @default.
- W2149144611 cites W2187067613 @default.
- W2149144611 cites W2314442209 @default.
- W2149144611 cites W2317544664 @default.
- W2149144611 doi "https://doi.org/10.3109/10520295.2011.591834" @default.
- W2149144611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21838613" @default.
- W2149144611 hasPublicationYear "2011" @default.
- W2149144611 type Work @default.
- W2149144611 sameAs 2149144611 @default.
- W2149144611 citedByCount "2" @default.
- W2149144611 countsByYear W21491446112013 @default.
- W2149144611 crossrefType "journal-article" @default.
- W2149144611 hasAuthorship W2149144611A5008581924 @default.
- W2149144611 hasAuthorship W2149144611A5042723430 @default.
- W2149144611 hasAuthorship W2149144611A5049477662 @default.
- W2149144611 hasAuthorship W2149144611A5051965167 @default.
- W2149144611 hasAuthorship W2149144611A5070525280 @default.
- W2149144611 hasAuthorship W2149144611A5074231400 @default.
- W2149144611 hasAuthorship W2149144611A5089276174 @default.
- W2149144611 hasAuthorship W2149144611A5090428050 @default.
- W2149144611 hasConcept C10205521 @default.
- W2149144611 hasConcept C121608353 @default.
- W2149144611 hasConcept C126322002 @default.
- W2149144611 hasConcept C142724271 @default.
- W2149144611 hasConcept C16930146 @default.
- W2149144611 hasConcept C204232928 @default.
- W2149144611 hasConcept C207886595 @default.
- W2149144611 hasConcept C2775934546 @default.
- W2149144611 hasConcept C2777007597 @default.
- W2149144611 hasConcept C2777714996 @default.
- W2149144611 hasConcept C2778256501 @default.
- W2149144611 hasConcept C2779013556 @default.
- W2149144611 hasConcept C2780057860 @default.
- W2149144611 hasConcept C28328180 @default.
- W2149144611 hasConcept C54355233 @default.
- W2149144611 hasConcept C71924100 @default.
- W2149144611 hasConcept C74864618 @default.
- W2149144611 hasConcept C86803240 @default.
- W2149144611 hasConceptScore W2149144611C10205521 @default.
- W2149144611 hasConceptScore W2149144611C121608353 @default.
- W2149144611 hasConceptScore W2149144611C126322002 @default.
- W2149144611 hasConceptScore W2149144611C142724271 @default.
- W2149144611 hasConceptScore W2149144611C16930146 @default.
- W2149144611 hasConceptScore W2149144611C204232928 @default.
- W2149144611 hasConceptScore W2149144611C207886595 @default.
- W2149144611 hasConceptScore W2149144611C2775934546 @default.
- W2149144611 hasConceptScore W2149144611C2777007597 @default.
- W2149144611 hasConceptScore W2149144611C2777714996 @default.
- W2149144611 hasConceptScore W2149144611C2778256501 @default.
- W2149144611 hasConceptScore W2149144611C2779013556 @default.
- W2149144611 hasConceptScore W2149144611C2780057860 @default.
- W2149144611 hasConceptScore W2149144611C28328180 @default.
- W2149144611 hasConceptScore W2149144611C54355233 @default.
- W2149144611 hasConceptScore W2149144611C71924100 @default.
- W2149144611 hasConceptScore W2149144611C74864618 @default.
- W2149144611 hasConceptScore W2149144611C86803240 @default.
- W2149144611 hasIssue "1" @default.
- W2149144611 hasLocation W21491446111 @default.
- W2149144611 hasLocation W21491446112 @default.
- W2149144611 hasOpenAccess W2149144611 @default.
- W2149144611 hasPrimaryLocation W21491446111 @default.
- W2149144611 hasRelatedWork W1986619006 @default.
- W2149144611 hasRelatedWork W2168580299 @default.
- W2149144611 hasRelatedWork W2188035050 @default.
- W2149144611 hasRelatedWork W2355792856 @default.
- W2149144611 hasRelatedWork W2370812173 @default.
- W2149144611 hasRelatedWork W2388984648 @default.
- W2149144611 hasRelatedWork W2742519752 @default.
- W2149144611 hasRelatedWork W3029310622 @default.
- W2149144611 hasRelatedWork W3030191502 @default.
- W2149144611 hasRelatedWork W3031112875 @default.
- W2149144611 hasVolume "87" @default.
- W2149144611 isParatext "false" @default.
- W2149144611 isRetracted "false" @default.
- W2149144611 magId "2149144611" @default.
- W2149144611 workType "article" @default.