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- W2149171683 abstract "There has been interest in using environmental screening procedures for enhancing the metabolomic production profiles by fungi which are of pharmaceutical interest. This study examined two ecologically distinct species, Epicoccum nigrum and Sarophorum palmicola , in solid substrate fermentation systems over a range of water availability conditions (water activity, a W ). Total secondary metabolite profiles were obtained by HPLC + diode array detection after 14 days incubation on cereal-based substrates in relation to four a W treatments. Temporal studies (24 d, E. nigrum and 18 d, S. palmicola ) showed that metabolite production profiles varied markedly between the two fungi. For E. nigrum , metabolite production generally increased with reduction in a W , and was optimal in the range 0.99 – 0.97. In contrast to this, for S. palmicola , metabolite production was restricted to the highest a W level used, 0.998, and declined to zero at 0.99 a W . Statistical analysis revealed that time, a W and their interactions were significant in all cases (p" @default.
- W2149171683 created "2016-06-24" @default.
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- W2149171683 date "2005-02-01" @default.
- W2149171683 modified "2023-09-26" @default.
- W2149171683 title "Water availability and metabolomic profiles of Epicoccum nigrum and Sarophorum palmicola grown in solid substrate fermentation systems" @default.
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- W2149171683 doi "https://doi.org/10.1017/s0269915x05001035" @default.
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