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• W2149177534 abstract "Numerous studies have been conducted investigating the reproductive toxicology of ethanol, the overwhelming majority concerning the adverse effects of consuming alcohol in beverages during pregnancy. Because many of the in vivo studies were designed to model alcoholism, they used comparatively high doses and assessed relatively few endpoints. Outcomes may have been affected by disturbances of metabolism at such high exposures, giving rise to secondary effects on development. The available data on ethanol from conventional developmental toxicity study test methods of the type used for regulatory hazard assessment of chemicals are limited. It is in this context, however, i.e. the use of ethanol as an industrial chemical rather than as a component of beverages, that this review is based. Using the usual criteria applied for the purpose of hazard assessment of industrial chemicals, it is concluded that there is no evidence that industrial exposure to ethanol is a developmental toxicity hazard. Developmental toxicity may result from drinking alcoholic beverages, the threshold level for all aspects of which has yet to be de fi ned. This is not, however, considered relevant to the low blood alcohol concentrations resulting from any conceivable inhalation or dermal exposure in the workplace or through the directed use of any consumer product containing ethanol." @default.
• W2149177534 created "2016-06-24" @default.
• W2149177534 creator A5044405652 @default.
• W2149177534 date "2003-01-01" @default.
• W2149177534 modified "2023-10-12" @default.
• W2149177534 title "Relevance of the developmental toxicity of ethanol in the occupational setting: a review" @default.
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• W2149177534 doi "https://doi.org/10.1002/jat.937" @default.
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• W2149177534 hasPublicationYear "2003" @default.
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