Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149179622> ?p ?o ?g. }
- W2149179622 endingPage "60" @default.
- W2149179622 startingPage "56" @default.
- W2149179622 abstract "Objective We aimed to investigate the effects of unilateral total salpingectomy procedure on ovarian follicular reserve, apoptosis, and proliferating cell nuclear antigen (PCNA) staining in this study. Study design Fourteen female Wistar Albino rats of 12 weeks were randomly divided into two groups. Abdomen midline incision was conducted under general anesthesia. Group 1(G1) (n = 7): Group in which only the abdomen was opened and closed, Group 2(G2) (n = 7): Group that underwent right total salpingectomy. After 1 month, abdomens of all rats were opened. Ovaries were macroscopically evaluated. Right ovarian tissue was quickly removed, fixed in 10% formaldehyde, and paraffin blocks were prepared.’ The existence of fibrosis was identified with the usage of light microscope. Follicles were microscopically classified and counted. The prevalence of cytoplasmic immune staining and TUNEL staining was scored semi-quantitatively. Statistical analysis : SPSS 17.0 software was used for the statistical analysis of data. First, Kruskal–Wallis variance analysis was conducted, and then Mann–Whitney U test was utilized for inter-group dual comparisons for parameters found as p < 0.05. Results While the number of CL was found out dramatically high, secondary follicle count was found out to be significantly low in G2. Also in G2, although the number of atretic follicle and fibrosis were found out significantly increased, and the score of the angiogenesis was found to be significantly decreased in CL. When compared PCNA immunoreactivity in granulosa cells with the control group, there was a significant decrease in G2. When compared the malondialdehyde (MDA) immunoreactivity with G1 a significant increase was established in G2. Apoptosis score of ovarian follicles in granulosa cells was significantly higher in G2. Conclusions In this experimental study, the decrease in the ovarian reserve and PCNA staning of granulosa cells, an increase in apoptosis, fibrosis and the number of atretic follicles in unilateral total salpingectomy operation were analyzed in rats. We found out significantly higher MDA staining rates in G2 in comparison to in G1. According to the study, the unilateral total salpingectomy procedure can damage to the same side ovarian tissue by means of the ischemia and reperfusion injury at the ovarian tissue." @default.
- W2149179622 created "2016-06-24" @default.
- W2149179622 creator A5018555705 @default.
- W2149179622 creator A5024939706 @default.
- W2149179622 creator A5044355259 @default.
- W2149179622 creator A5052832399 @default.
- W2149179622 creator A5059747891 @default.
- W2149179622 creator A5067818741 @default.
- W2149179622 creator A5080306709 @default.
- W2149179622 date "2015-05-01" @default.
- W2149179622 modified "2023-09-27" @default.
- W2149179622 title "Investigation of the effects of unilateral total salpingectomy on ovarian proliferating cell nuclear antigen and follicular reserve: experimental study" @default.
- W2149179622 cites W1915589840 @default.
- W2149179622 cites W1967971828 @default.
- W2149179622 cites W1979917621 @default.
- W2149179622 cites W1994489910 @default.
- W2149179622 cites W1998445016 @default.
- W2149179622 cites W2002146218 @default.
- W2149179622 cites W2005250335 @default.
- W2149179622 cites W2009916250 @default.
- W2149179622 cites W2015039463 @default.
- W2149179622 cites W2016048383 @default.
- W2149179622 cites W2045165475 @default.
- W2149179622 cites W2047173037 @default.
- W2149179622 cites W2061949605 @default.
- W2149179622 cites W2075776805 @default.
- W2149179622 cites W2123791519 @default.
- W2149179622 cites W2126668136 @default.
- W2149179622 cites W2129639911 @default.
- W2149179622 cites W2134353144 @default.
- W2149179622 cites W2142538175 @default.
- W2149179622 cites W2160329305 @default.
- W2149179622 cites W2160336344 @default.
- W2149179622 cites W2168860685 @default.
- W2149179622 cites W2141313705 @default.
- W2149179622 doi "https://doi.org/10.1016/j.ejogrb.2015.02.028" @default.
- W2149179622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25790915" @default.
- W2149179622 hasPublicationYear "2015" @default.
- W2149179622 type Work @default.
- W2149179622 sameAs 2149179622 @default.
- W2149179622 citedByCount "14" @default.
- W2149179622 countsByYear W21491796222015 @default.
- W2149179622 countsByYear W21491796222016 @default.
- W2149179622 countsByYear W21491796222017 @default.
- W2149179622 countsByYear W21491796222018 @default.
- W2149179622 countsByYear W21491796222020 @default.
- W2149179622 countsByYear W21491796222021 @default.
- W2149179622 countsByYear W21491796222022 @default.
- W2149179622 crossrefType "journal-article" @default.
- W2149179622 hasAuthorship W2149179622A5018555705 @default.
- W2149179622 hasAuthorship W2149179622A5024939706 @default.
- W2149179622 hasAuthorship W2149179622A5044355259 @default.
- W2149179622 hasAuthorship W2149179622A5052832399 @default.
- W2149179622 hasAuthorship W2149179622A5059747891 @default.
- W2149179622 hasAuthorship W2149179622A5067818741 @default.
- W2149179622 hasAuthorship W2149179622A5080306709 @default.
- W2149179622 hasConcept C102570824 @default.
- W2149179622 hasConcept C126322002 @default.
- W2149179622 hasConcept C142724271 @default.
- W2149179622 hasConcept C16685009 @default.
- W2149179622 hasConcept C187785154 @default.
- W2149179622 hasConcept C204232928 @default.
- W2149179622 hasConcept C2776018949 @default.
- W2149179622 hasConcept C2776600139 @default.
- W2149179622 hasConcept C2776659692 @default.
- W2149179622 hasConcept C2777688143 @default.
- W2149179622 hasConcept C2778324911 @default.
- W2149179622 hasConcept C2779234561 @default.
- W2149179622 hasConcept C2780164438 @default.
- W2149179622 hasConcept C2780536345 @default.
- W2149179622 hasConcept C2780559512 @default.
- W2149179622 hasConcept C34688535 @default.
- W2149179622 hasConcept C54355233 @default.
- W2149179622 hasConcept C5512455 @default.
- W2149179622 hasConcept C71924100 @default.
- W2149179622 hasConcept C74864618 @default.
- W2149179622 hasConcept C86803240 @default.
- W2149179622 hasConceptScore W2149179622C102570824 @default.
- W2149179622 hasConceptScore W2149179622C126322002 @default.
- W2149179622 hasConceptScore W2149179622C142724271 @default.
- W2149179622 hasConceptScore W2149179622C16685009 @default.
- W2149179622 hasConceptScore W2149179622C187785154 @default.
- W2149179622 hasConceptScore W2149179622C204232928 @default.
- W2149179622 hasConceptScore W2149179622C2776018949 @default.
- W2149179622 hasConceptScore W2149179622C2776600139 @default.
- W2149179622 hasConceptScore W2149179622C2776659692 @default.
- W2149179622 hasConceptScore W2149179622C2777688143 @default.
- W2149179622 hasConceptScore W2149179622C2778324911 @default.
- W2149179622 hasConceptScore W2149179622C2779234561 @default.
- W2149179622 hasConceptScore W2149179622C2780164438 @default.
- W2149179622 hasConceptScore W2149179622C2780536345 @default.
- W2149179622 hasConceptScore W2149179622C2780559512 @default.
- W2149179622 hasConceptScore W2149179622C34688535 @default.
- W2149179622 hasConceptScore W2149179622C54355233 @default.
- W2149179622 hasConceptScore W2149179622C5512455 @default.
- W2149179622 hasConceptScore W2149179622C71924100 @default.
- W2149179622 hasConceptScore W2149179622C74864618 @default.
- W2149179622 hasConceptScore W2149179622C86803240 @default.