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• W2149196660 startingPage "31" @default.
• W2149196660 abstract "ABSTRACT The mitochondrial component coenzyme Q 10 (CoQ 10 b ) Has been used for many years as a Dietary supplement intended to promote good health by trapping free radicals, thus preventing lipid peroxidation and DNA damage. We have tested its use as a generic anti‐apoptotic compound and have found that its ability to protect against apoptosis varies depending on both cell type and mode of cell death induction. We have further established that this protection may be mediated by its effect on mitochondrial function and viability. We provide additional evidence that CoQ 10 's protective effect on mitochondrial membrane potnetial does not always result in altered mitochondrial enzyme activity and neither does it guarantee survival. These observations open the way for further investigations into the mechanisms involved in mitochondrial control of apoptosis." @default.
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• W2149196660 date "1999-12-01" @default.
• W2149196660 modified "2023-10-11" @default.
• W2149196660 title "Coenzyme Q₁₀Can in Some Circumstances Block Apoptosis, and This Effect Is Mediated through Mitochondria" @default.
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• W2149196660 doi "https://doi.org/10.1111/j.1749-6632.1999.tb07920.x" @default.
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