Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149205609> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2149205609 endingPage "566" @default.
- W2149205609 startingPage "563" @default.
- W2149205609 abstract "Intracerebroventricular (ICV) microinjection of glucagon (0.0025-2.5 micrograms) produced significant dose-dependent hyperglycemia in mice. This hyperglycemic effect was prevented by pretreatment with the sympathetic ganglionic blocker chlorisondamine chloride or bilateral adrenalectomy plus chemical sympathectomy with 6-hydroxydopamine. Similar pretreatments had no effect on the plasma glucose responses to systemic glucagon administration. Pretreatment with somatostatin, which blocks pancreatic glucagon secretion had no effect on the hyperglycemic response to central glucagon administration. The results suggest that the increase in plasma glucose following central glucagon administration is mediated by combined action of adrenal and sympathetic amines to stimulate hepatic glucose production, or additionally to inhibit insulin release from the pancreas. The possible involvement of glucagon in the central nervous system in systemic glucoregulation is discussed." @default.
- W2149205609 created "2016-06-24" @default.
- W2149205609 creator A5069775419 @default.
- W2149205609 date "1986-01-01" @default.
- W2149205609 modified "2023-10-15" @default.
- W2149205609 title "Central glucagon-induced hyperglycemia is mediated by combined activation of the adrenal medulla and sympathetic nerve endings" @default.
- W2149205609 cites W125656417 @default.
- W2149205609 cites W1965927574 @default.
- W2149205609 cites W1975322235 @default.
- W2149205609 cites W1984619996 @default.
- W2149205609 cites W1985939147 @default.
- W2149205609 cites W1987262644 @default.
- W2149205609 cites W1994112692 @default.
- W2149205609 cites W1996876787 @default.
- W2149205609 cites W2005926028 @default.
- W2149205609 cites W2006103366 @default.
- W2149205609 cites W2009051567 @default.
- W2149205609 cites W2016710770 @default.
- W2149205609 cites W2044985824 @default.
- W2149205609 cites W2058435144 @default.
- W2149205609 cites W2063722863 @default.
- W2149205609 cites W2065408322 @default.
- W2149205609 cites W2089629071 @default.
- W2149205609 cites W2089974661 @default.
- W2149205609 cites W2120120377 @default.
- W2149205609 cites W2157164734 @default.
- W2149205609 cites W2260757043 @default.
- W2149205609 cites W230545017 @default.
- W2149205609 cites W2412133373 @default.
- W2149205609 cites W2735178939 @default.
- W2149205609 cites W4243537836 @default.
- W2149205609 doi "https://doi.org/10.1016/0031-9384(86)90286-6" @default.
- W2149205609 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3092255" @default.
- W2149205609 hasPublicationYear "1986" @default.
- W2149205609 type Work @default.
- W2149205609 sameAs 2149205609 @default.
- W2149205609 citedByCount "24" @default.
- W2149205609 countsByYear W21492056092012 @default.
- W2149205609 countsByYear W21492056092013 @default.
- W2149205609 countsByYear W21492056092014 @default.
- W2149205609 countsByYear W21492056092016 @default.
- W2149205609 countsByYear W21492056092017 @default.
- W2149205609 countsByYear W21492056092023 @default.
- W2149205609 crossrefType "journal-article" @default.
- W2149205609 hasAuthorship W2149205609A5069775419 @default.
- W2149205609 hasConcept C126322002 @default.
- W2149205609 hasConcept C134018914 @default.
- W2149205609 hasConcept C2775894120 @default.
- W2149205609 hasConcept C2776533406 @default.
- W2149205609 hasConcept C2777012931 @default.
- W2149205609 hasConcept C2777391703 @default.
- W2149205609 hasConcept C2777597313 @default.
- W2149205609 hasConcept C2778563252 @default.
- W2149205609 hasConcept C2779190097 @default.
- W2149205609 hasConcept C2779306644 @default.
- W2149205609 hasConcept C2780352109 @default.
- W2149205609 hasConcept C2908748658 @default.
- W2149205609 hasConcept C62525196 @default.
- W2149205609 hasConcept C71924100 @default.
- W2149205609 hasConcept C84393581 @default.
- W2149205609 hasConceptScore W2149205609C126322002 @default.
- W2149205609 hasConceptScore W2149205609C134018914 @default.
- W2149205609 hasConceptScore W2149205609C2775894120 @default.
- W2149205609 hasConceptScore W2149205609C2776533406 @default.
- W2149205609 hasConceptScore W2149205609C2777012931 @default.
- W2149205609 hasConceptScore W2149205609C2777391703 @default.
- W2149205609 hasConceptScore W2149205609C2777597313 @default.
- W2149205609 hasConceptScore W2149205609C2778563252 @default.
- W2149205609 hasConceptScore W2149205609C2779190097 @default.
- W2149205609 hasConceptScore W2149205609C2779306644 @default.
- W2149205609 hasConceptScore W2149205609C2780352109 @default.
- W2149205609 hasConceptScore W2149205609C2908748658 @default.
- W2149205609 hasConceptScore W2149205609C62525196 @default.
- W2149205609 hasConceptScore W2149205609C71924100 @default.
- W2149205609 hasConceptScore W2149205609C84393581 @default.
- W2149205609 hasIssue "4" @default.
- W2149205609 hasLocation W21492056091 @default.
- W2149205609 hasLocation W21492056092 @default.
- W2149205609 hasOpenAccess W2149205609 @default.
- W2149205609 hasPrimaryLocation W21492056091 @default.
- W2149205609 hasRelatedWork W1980720899 @default.
- W2149205609 hasRelatedWork W1992078922 @default.
- W2149205609 hasRelatedWork W2003144879 @default.
- W2149205609 hasRelatedWork W2056882537 @default.
- W2149205609 hasRelatedWork W2080562066 @default.
- W2149205609 hasRelatedWork W2081584694 @default.
- W2149205609 hasRelatedWork W2084753756 @default.
- W2149205609 hasRelatedWork W2149205609 @default.
- W2149205609 hasRelatedWork W2409434193 @default.
- W2149205609 hasRelatedWork W2592864982 @default.
- W2149205609 hasVolume "37" @default.
- W2149205609 isParatext "false" @default.
- W2149205609 isRetracted "false" @default.
- W2149205609 magId "2149205609" @default.
- W2149205609 workType "article" @default.