FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149233865> ?p ?o ?g. }

• W2149233865 endingPage "455" @default.
• W2149233865 startingPage "448" @default.
• W2149233865 abstract "Background & Aims: The first therapeutic experiences with the conventional photosensitizer dihematoporphyrinester in the treatment of Barrett's esophagus show the curative potential of photodynamic therapy (PDT). The aim of this study was to test 5-aminolevulinic acid (5-ALA)-induced protoporphyrin IX, a photosensitizer with a high mucosa specificity without phototoxic side effects on the skin, as a new form of PDT. Methods: Thirty-two patients (mean age, 68.5 years) with histologically proven high-grade dysplasia (n = 10) and mucosal cancer (n = 22) in Barrett's esophagus were treated. Four to 6 hours after oral ingestion of 5-ALA (dose, 60 mg/kg body wt), irradiation was conducted with a dye laser system (635 nm) with a light dose of 150 J/cm2. The patients received 20–80 mg omeprazole daily after PDT. Results: High-grade dysplasia was eradicated in all patients (10 of 10), and mucosal cancer was eliminated in 17 of 22 patients (77%) at a mean follow-up of 9.9 months (range, 1–30 months). All tumors ≤2 mm in thickness were completely ablated (17 of 17). The method-related mortality and morbidity was 0%. Conclusions: Severe dysplasia and thin (≤2 mm) mucosal cancer of Barrett's esophagus can be completely ablated. PDT might offer a minimally invasive treatment modality as an alternative to esophagectomy.GASTROENTEROLOGY 1998;114:448-455" @default.
• W2149233865 created "2016-06-24" @default.
• W2149233865 creator A5016594964 @default.
• W2149233865 creator A5023060755 @default.
• W2149233865 creator A5023485183 @default.
• W2149233865 creator A5054331215 @default.
• W2149233865 creator A5059688508 @default.
• W2149233865 creator A5070459365 @default.
• W2149233865 creator A5084527744 @default.
• W2149233865 date "1998-03-01" @default.
• W2149233865 modified "2023-10-16" @default.
• W2149233865 title "Photodynamic ablation of high-grade dysplasia and early cancer in Barrett's esophagus by means of 5-aminolevulinic acid" @default.
• W2149233865 cites W1491111636 @default.
• W2149233865 cites W1536161276 @default.
• W2149233865 cites W1568080413 @default.
• W2149233865 cites W1625189041 @default.
• W2149233865 cites W1867956748 @default.
• W2149233865 cites W1883444875 @default.
• W2149233865 cites W1964219512 @default.
• W2149233865 cites W1987623577 @default.
• W2149233865 cites W1988141366 @default.
• W2149233865 cites W1990864286 @default.
• W2149233865 cites W1991767819 @default.
• W2149233865 cites W1993234428 @default.
• W2149233865 cites W1993236245 @default.
• W2149233865 cites W2036243900 @default.
• W2149233865 cites W2042573229 @default.
• W2149233865 cites W2044803197 @default.
• W2149233865 cites W2047889682 @default.
• W2149233865 cites W2053397394 @default.
• W2149233865 cites W2055796784 @default.
• W2149233865 cites W2056484082 @default.
• W2149233865 cites W2072823589 @default.
• W2149233865 cites W2073339937 @default.
• W2149233865 cites W2074645799 @default.
• W2149233865 cites W2080349482 @default.
• W2149233865 cites W2088044717 @default.
• W2149233865 cites W2109966571 @default.
• W2149233865 cites W2132658626 @default.
• W2149233865 cites W2150240082 @default.
• W2149233865 cites W2154551981 @default.
• W2149233865 cites W4239269637 @default.
• W2149233865 cites W4250095675 @default.
• W2149233865 cites W4255683556 @default.
• W2149233865 cites W4294350674 @default.
• W2149233865 doi "https://doi.org/10.1016/s0016-5085(98)70527-x" @default.
• W2149233865 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9496934" @default.
• W2149233865 hasPublicationYear "1998" @default.
• W2149233865 type Work @default.
• W2149233865 sameAs 2149233865 @default.
• W2149233865 citedByCount "382" @default.
• W2149233865 countsByYear W21492338652012 @default.
• W2149233865 countsByYear W21492338652013 @default.
• W2149233865 countsByYear W21492338652014 @default.
• W2149233865 countsByYear W21492338652015 @default.
• W2149233865 countsByYear W21492338652016 @default.
• W2149233865 countsByYear W21492338652017 @default.
• W2149233865 countsByYear W21492338652018 @default.
• W2149233865 countsByYear W21492338652019 @default.
• W2149233865 countsByYear W21492338652020 @default.
• W2149233865 countsByYear W21492338652021 @default.
• W2149233865 countsByYear W21492338652022 @default.
• W2149233865 countsByYear W21492338652023 @default.
• W2149233865 crossrefType "journal-article" @default.
• W2149233865 hasAuthorship W2149233865A5016594964 @default.
• W2149233865 hasAuthorship W2149233865A5023060755 @default.
• W2149233865 hasAuthorship W2149233865A5023485183 @default.
• W2149233865 hasAuthorship W2149233865A5054331215 @default.
• W2149233865 hasAuthorship W2149233865A5059688508 @default.
• W2149233865 hasAuthorship W2149233865A5070459365 @default.
• W2149233865 hasAuthorship W2149233865A5084527744 @default.
• W2149233865 hasBestOaLocation W21492338651 @default.
• W2149233865 hasConcept C121608353 @default.
• W2149233865 hasConcept C126322002 @default.
• W2149233865 hasConcept C178790620 @default.
• W2149233865 hasConcept C185592680 @default.
• W2149233865 hasConcept C2775894508 @default.
• W2149233865 hasConcept C2777297899 @default.
• W2149233865 hasConcept C2777819096 @default.
• W2149233865 hasConcept C2778589982 @default.
• W2149233865 hasConcept C2778902805 @default.
• W2149233865 hasConcept C2779671804 @default.
• W2149233865 hasConcept C2779742542 @default.
• W2149233865 hasConcept C2780323790 @default.
• W2149233865 hasConcept C2781182431 @default.
• W2149233865 hasConcept C2781323092 @default.
• W2149233865 hasConcept C2781469039 @default.
• W2149233865 hasConcept C71924100 @default.
• W2149233865 hasConcept C90924648 @default.
• W2149233865 hasConceptScore W2149233865C121608353 @default.
• W2149233865 hasConceptScore W2149233865C126322002 @default.
• W2149233865 hasConceptScore W2149233865C178790620 @default.
• W2149233865 hasConceptScore W2149233865C185592680 @default.
• W2149233865 hasConceptScore W2149233865C2775894508 @default.
• W2149233865 hasConceptScore W2149233865C2777297899 @default.
• W2149233865 hasConceptScore W2149233865C2777819096 @default.
• W2149233865 hasConceptScore W2149233865C2778589982 @default.
• W2149233865 hasConceptScore W2149233865C2778902805 @default.

• next