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• W2149254976 abstract "A novel method for asymmetric synthesis of trans-2,3-disubstituted indolines has been developed. The strategy involves the (−)-sparteine-mediated electrophilic substitution of 2-benzyl N-pivaloylaniline with aromatic or α,β-unsaturated aldehydes and subsequent intramolecular nucleophilic substitution. The simple protocol for two-step process can produce highly enantioenriched indolines 3a–o up to 98:2 er." @default.
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• W2149254976 date "2011-12-19" @default.
• W2149254976 modified "2023-09-26" @default.
• W2149254976 title "Asymmetric Synthesis of <i>trans</i>-2,3-Disubstituted Indoline Derivatives" @default.
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• W2149254976 doi "https://doi.org/10.1021/jo2023526" @default.
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