FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149256613> ?p ?o ?g. }

• W2149256613 endingPage "2227" @default.
• W2149256613 startingPage "2222" @default.
• W2149256613 abstract "Background- Vascular smooth muscle cell (VSMC) proliferation is a critical factor in the neointima formation that causes restenosis after coronary angioplasty (PTCA). Desferri-exochelin 772SM (D-EXO), a highly diffusible, lipophilic iron chelator secreted by Mycobacterium tuberculosis, inhibits proliferation of VSMCs in culture. We hypothesized that treatment with D-EXO would inhibit neointima formation in balloon-injured vessels in vivo. Methods and Results- We subjected 24 pigs to overstretch coronary artery injury with standard PTCA balloons and then administered intramural injections of either D-EXO (n=14) or vehicle (n=10) through an Infiltrator catheter. Treatments were randomized, and the investigators were blinded with regard to treatment group until data analysis was completed. One month later, we euthanized the pigs, excised the injured coronary segments, made multiple sections of each segment, and identified the site of maximal neointima formation. An injury score based on the degree of disruption of the internal or external elastic lamina or media was assigned. D-EXO reduced stenosis index (neointima area divided by the area within the internal elastic lamina), adjusted for injury score, by 47%. Neointima thickness was also reduced. Conclusions- D-EXO, injected intramurally, substantially inhibited formation of neointima in a porcine vascular injury model." @default.
• W2149256613 created "2016-06-24" @default.
• W2149256613 creator A5015344354 @default.
• W2149256613 creator A5016770881 @default.
• W2149256613 creator A5025171316 @default.
• W2149256613 creator A5037778810 @default.
• W2149256613 creator A5040703804 @default.
• W2149256613 creator A5062026780 @default.
• W2149256613 creator A5066688072 @default.
• W2149256613 creator A5086717243 @default.
• W2149256613 date "2001-10-30" @default.
• W2149256613 modified "2023-10-03" @default.
• W2149256613 title "An Iron-Binding Exochelin Prevents Restenosis Due to Coronary Artery Balloon Injury in a Porcine Model" @default.
• W2149256613 cites W1510505825 @default.
• W2149256613 cites W1965179617 @default.
• W2149256613 cites W1970043831 @default.
• W2149256613 cites W1979219149 @default.
• W2149256613 cites W2002155023 @default.
• W2149256613 cites W2021851372 @default.
• W2149256613 cites W2034487226 @default.
• W2149256613 cites W2036805568 @default.
• W2149256613 cites W2040493219 @default.
• W2149256613 cites W2046998375 @default.
• W2149256613 cites W2068385607 @default.
• W2149256613 cites W2074919956 @default.
• W2149256613 cites W2083612433 @default.
• W2149256613 cites W2086543273 @default.
• W2149256613 cites W2135194931 @default.
• W2149256613 cites W2330609598 @default.
• W2149256613 cites W2338244399 @default.
• W2149256613 doi "https://doi.org/10.1161/hc4301.097194" @default.
• W2149256613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11684635" @default.
• W2149256613 hasPublicationYear "2001" @default.
• W2149256613 type Work @default.
• W2149256613 sameAs 2149256613 @default.
• W2149256613 citedByCount "18" @default.
• W2149256613 countsByYear W21492566132012 @default.
• W2149256613 countsByYear W21492566132013 @default.
• W2149256613 countsByYear W21492566132014 @default.
• W2149256613 countsByYear W21492566132022 @default.
• W2149256613 crossrefType "journal-article" @default.
• W2149256613 hasAuthorship W2149256613A5015344354 @default.
• W2149256613 hasAuthorship W2149256613A5016770881 @default.
• W2149256613 hasAuthorship W2149256613A5025171316 @default.
• W2149256613 hasAuthorship W2149256613A5037778810 @default.
• W2149256613 hasAuthorship W2149256613A5040703804 @default.
• W2149256613 hasAuthorship W2149256613A5062026780 @default.
• W2149256613 hasAuthorship W2149256613A5066688072 @default.
• W2149256613 hasAuthorship W2149256613A5086717243 @default.
• W2149256613 hasBestOaLocation W21492566131 @default.
• W2149256613 hasConcept C126322002 @default.
• W2149256613 hasConcept C139059822 @default.
• W2149256613 hasConcept C150903083 @default.
• W2149256613 hasConcept C164705383 @default.
• W2149256613 hasConcept C207001950 @default.
• W2149256613 hasConcept C2776205367 @default.
• W2149256613 hasConcept C2776820930 @default.
• W2149256613 hasConcept C2777339539 @default.
• W2149256613 hasConcept C2778283817 @default.
• W2149256613 hasConcept C2778583881 @default.
• W2149256613 hasConcept C2779395532 @default.
• W2149256613 hasConcept C2780007028 @default.
• W2149256613 hasConcept C2780326628 @default.
• W2149256613 hasConcept C2992686903 @default.
• W2149256613 hasConcept C2993470428 @default.
• W2149256613 hasConcept C71924100 @default.
• W2149256613 hasConcept C86803240 @default.
• W2149256613 hasConceptScore W2149256613C126322002 @default.
• W2149256613 hasConceptScore W2149256613C139059822 @default.
• W2149256613 hasConceptScore W2149256613C150903083 @default.
• W2149256613 hasConceptScore W2149256613C164705383 @default.
• W2149256613 hasConceptScore W2149256613C207001950 @default.
• W2149256613 hasConceptScore W2149256613C2776205367 @default.
• W2149256613 hasConceptScore W2149256613C2776820930 @default.
• W2149256613 hasConceptScore W2149256613C2777339539 @default.
• W2149256613 hasConceptScore W2149256613C2778283817 @default.
• W2149256613 hasConceptScore W2149256613C2778583881 @default.
• W2149256613 hasConceptScore W2149256613C2779395532 @default.
• W2149256613 hasConceptScore W2149256613C2780007028 @default.
• W2149256613 hasConceptScore W2149256613C2780326628 @default.
• W2149256613 hasConceptScore W2149256613C2992686903 @default.
• W2149256613 hasConceptScore W2149256613C2993470428 @default.
• W2149256613 hasConceptScore W2149256613C71924100 @default.
• W2149256613 hasConceptScore W2149256613C86803240 @default.
• W2149256613 hasIssue "18" @default.
• W2149256613 hasLocation W21492566131 @default.
• W2149256613 hasLocation W21492566132 @default.
• W2149256613 hasOpenAccess W2149256613 @default.
• W2149256613 hasPrimaryLocation W21492566131 @default.
• W2149256613 hasRelatedWork W1963881127 @default.
• W2149256613 hasRelatedWork W1964723030 @default.
• W2149256613 hasRelatedWork W1992705822 @default.
• W2149256613 hasRelatedWork W2102133507 @default.
• W2149256613 hasRelatedWork W2136191582 @default.
• W2149256613 hasRelatedWork W2180160231 @default.
• W2149256613 hasRelatedWork W2369935680 @default.
• W2149256613 hasRelatedWork W2379694518 @default.
• W2149256613 hasRelatedWork W2386733398 @default.

• next