FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149257862> ?p ?o ?g. }

• W2149257862 endingPage "25" @default.
• W2149257862 startingPage "17" @default.
• W2149257862 abstract "A novel oxidase, catalyzing in the presence of oxygen the removal of four hydrogen atoms from a number of tetrahydroprotoberberines with simultaneous production of 1 mol H2O2 and H2O each, has been discovered and purified to homogeneity from Berberis wilsoniae cell cultures. This enzyme, (S)-tetrahydroprotoberberine oxidase, exhibited strict specificity for the (S)-enantiomer of tetrahydroprotoberberines and 1-benzylisoquinoline alkaloids, a pH optimum at 8.9, a molecular mass of 105 kDa and consisted of two subunits each of 53 kDa and covalently bound flavin. The Km values for (S)-scoulerine and (S)-norreticuline were 25 microM and 150 microM respectively. Concentration of the end-products, either protoberberines or H2O2, greater than 0.5 mM caused severe enzyme inhibition. This catalyst was responsible for the conversion of (S)-tetrahydrocolumbamine to the key intermediate, columbamine, in the metabolic pathway leading to berberine, jatrorrhizine and palmatine." @default.
• W2149257862 created "2016-06-24" @default.
• W2149257862 creator A5019116311 @default.
• W2149257862 creator A5071211916 @default.
• W2149257862 creator A5072214793 @default.
• W2149257862 date "1988-07-01" @default.
• W2149257862 modified "2023-10-10" @default.
• W2149257862 title "Purification and properties of (S)-tetrahydroprotoberberine oxidase from suspension-cultured cells of Berberis wilsoniae" @default.
• W2149257862 cites W1417132794 @default.
• W2149257862 cites W1455200103 @default.
• W2149257862 cites W1755682939 @default.
• W2149257862 cites W1946263363 @default.
• W2149257862 cites W1965377330 @default.
• W2149257862 cites W1967118561 @default.
• W2149257862 cites W1970082049 @default.
• W2149257862 cites W1975484145 @default.
• W2149257862 cites W1981262898 @default.
• W2149257862 cites W1986963239 @default.
• W2149257862 cites W1988570463 @default.
• W2149257862 cites W1989486865 @default.
• W2149257862 cites W1997487102 @default.
• W2149257862 cites W2010855809 @default.
• W2149257862 cites W2011932224 @default.
• W2149257862 cites W2020987696 @default.
• W2149257862 cites W2025347917 @default.
• W2149257862 cites W2026133178 @default.
• W2149257862 cites W2026682758 @default.
• W2149257862 cites W2055913160 @default.
• W2149257862 cites W2058858269 @default.
• W2149257862 cites W2061637029 @default.
• W2149257862 cites W2067491559 @default.
• W2149257862 cites W2077512489 @default.
• W2149257862 cites W2103988735 @default.
• W2149257862 cites W2128635872 @default.
• W2149257862 cites W2162941675 @default.
• W2149257862 cites W2019384702 @default.
• W2149257862 doi "https://doi.org/10.1111/j.1432-1033.1988.tb14160.x" @default.
• W2149257862 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3402447" @default.
• W2149257862 hasPublicationYear "1988" @default.
• W2149257862 type Work @default.
• W2149257862 sameAs 2149257862 @default.
• W2149257862 citedByCount "58" @default.
• W2149257862 countsByYear W21492578622012 @default.
• W2149257862 countsByYear W21492578622013 @default.
• W2149257862 countsByYear W21492578622014 @default.
• W2149257862 countsByYear W21492578622015 @default.
• W2149257862 countsByYear W21492578622017 @default.
• W2149257862 countsByYear W21492578622019 @default.
• W2149257862 countsByYear W21492578622020 @default.
• W2149257862 countsByYear W21492578622021 @default.
• W2149257862 countsByYear W21492578622022 @default.
• W2149257862 crossrefType "journal-article" @default.
• W2149257862 hasAuthorship W2149257862A5019116311 @default.
• W2149257862 hasAuthorship W2149257862A5071211916 @default.
• W2149257862 hasAuthorship W2149257862A5072214793 @default.
• W2149257862 hasBestOaLocation W21492578621 @default.
• W2149257862 hasConcept C181199279 @default.
• W2149257862 hasConcept C185592680 @default.
• W2149257862 hasConcept C2777288208 @default.
• W2149257862 hasConcept C2778439678 @default.
• W2149257862 hasConcept C2778746568 @default.
• W2149257862 hasConcept C2779733990 @default.
• W2149257862 hasConcept C2780116568 @default.
• W2149257862 hasConcept C33093398 @default.
• W2149257862 hasConcept C38485361 @default.
• W2149257862 hasConcept C533411734 @default.
• W2149257862 hasConcept C553450214 @default.
• W2149257862 hasConcept C55493867 @default.
• W2149257862 hasConcept C59822182 @default.
• W2149257862 hasConcept C71240020 @default.
• W2149257862 hasConcept C86803240 @default.
• W2149257862 hasConceptScore W2149257862C181199279 @default.
• W2149257862 hasConceptScore W2149257862C185592680 @default.
• W2149257862 hasConceptScore W2149257862C2777288208 @default.
• W2149257862 hasConceptScore W2149257862C2778439678 @default.
• W2149257862 hasConceptScore W2149257862C2778746568 @default.
• W2149257862 hasConceptScore W2149257862C2779733990 @default.
• W2149257862 hasConceptScore W2149257862C2780116568 @default.
• W2149257862 hasConceptScore W2149257862C33093398 @default.
• W2149257862 hasConceptScore W2149257862C38485361 @default.
• W2149257862 hasConceptScore W2149257862C533411734 @default.
• W2149257862 hasConceptScore W2149257862C553450214 @default.
• W2149257862 hasConceptScore W2149257862C55493867 @default.
• W2149257862 hasConceptScore W2149257862C59822182 @default.
• W2149257862 hasConceptScore W2149257862C71240020 @default.
• W2149257862 hasConceptScore W2149257862C86803240 @default.
• W2149257862 hasIssue "1" @default.
• W2149257862 hasLocation W21492578621 @default.
• W2149257862 hasLocation W21492578622 @default.
• W2149257862 hasOpenAccess W2149257862 @default.
• W2149257862 hasPrimaryLocation W21492578621 @default.
• W2149257862 hasRelatedWork W1971154989 @default.
• W2149257862 hasRelatedWork W2077250350 @default.
• W2149257862 hasRelatedWork W2143207960 @default.
• W2149257862 hasRelatedWork W2143877891 @default.
• W2149257862 hasRelatedWork W2149257862 @default.
• W2149257862 hasRelatedWork W2371386989 @default.
• W2149257862 hasRelatedWork W2372316143 @default.

• next