FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149274570> ?p ?o ?g. }

• W2149274570 endingPage "148" @default.
• W2149274570 startingPage "134" @default.
• W2149274570 abstract "Insect metamorphosis provides a valuable model for studying mechanisms of steroid hormone action on the nervous system during a dynamic phase of functional remodeling. TheDrosophila Broad Complex(BRC) holds a pivotal position in the gene expression cascade triggered by the molting hormone 20-hydroxyecdysone (20E) at the onset of metamorphosis. We previously demonstrated that theBRC,which encodes a family of zinc-finger transcription factors, is essential for transducing 20E signals into the morphogenetic movements and cellular assembly that alter the CNS from juvenile to adult form and function. We set out to examine the relationship ofBRCto two other genes,IMP-E1andDeformed(Dfd), involved in the metamorphic transition of the CNS. Representatives of the whole family ofBRCtranscript isoforms accumulate in the CNS during the larval-to-pupal transition and respond directly to 20Ein vitro. IMP-E1is also directly regulated by 20E, but its induction is independent ofBRC,revealing that 20E works through at least two pathways in the CNS. DFD expression is also independent ofBRCfunction. Surprisingly, BRC and DFD proteins are expressed in distinct, nonoverlapping subsets of neuronal nuclei of the subesophageal ganglion even though both are required for its migration into the head capsule. This suggests that the segment identity and ecdysone cascades operate in parallel to control region-specific reorganization during metamorphosis." @default.
• W2149274570 created "2016-06-24" @default.
• W2149274570 creator A5011637469 @default.
• W2149274570 creator A5085819632 @default.
• W2149274570 date "1998-06-01" @default.
• W2149274570 modified "2023-10-10" @default.
• W2149274570 title "Parallel Molecular Genetic Pathways Operate during CNS Metamorphosis inDrosophila" @default.
• W2149274570 cites W1665357660 @default.
• W2149274570 cites W1685133733 @default.
• W2149274570 cites W1907480816 @default.
• W2149274570 cites W1920119772 @default.
• W2149274570 cites W1971311303 @default.
• W2149274570 cites W1973334224 @default.
• W2149274570 cites W1976049591 @default.
• W2149274570 cites W1976851982 @default.
• W2149274570 cites W1979252107 @default.
• W2149274570 cites W1981430187 @default.
• W2149274570 cites W1984234078 @default.
• W2149274570 cites W1990766096 @default.
• W2149274570 cites W1994563997 @default.
• W2149274570 cites W1995267165 @default.
• W2149274570 cites W2008399291 @default.
• W2149274570 cites W2013319978 @default.
• W2149274570 cites W2015757393 @default.
• W2149274570 cites W2017111453 @default.
• W2149274570 cites W2018759259 @default.
• W2149274570 cites W2023218866 @default.
• W2149274570 cites W2030233815 @default.
• W2149274570 cites W2046209045 @default.
• W2149274570 cites W2046218009 @default.
• W2149274570 cites W2046238809 @default.
• W2149274570 cites W2047257157 @default.
• W2149274570 cites W2054609985 @default.
• W2149274570 cites W2055734100 @default.
• W2149274570 cites W2057745494 @default.
• W2149274570 cites W2058235418 @default.
• W2149274570 cites W2058773589 @default.
• W2149274570 cites W2060959074 @default.
• W2149274570 cites W2065972650 @default.
• W2149274570 cites W2067975978 @default.
• W2149274570 cites W2071157332 @default.
• W2149274570 cites W2071977571 @default.
• W2149274570 cites W2073133778 @default.
• W2149274570 cites W2073784494 @default.
• W2149274570 cites W2073934947 @default.
• W2149274570 cites W2075754851 @default.
• W2149274570 cites W2078119356 @default.
• W2149274570 cites W2097978662 @default.
• W2149274570 cites W2101143531 @default.
• W2149274570 cites W2103116478 @default.
• W2149274570 cites W2109284595 @default.
• W2149274570 cites W2110983797 @default.
• W2149274570 cites W2125161163 @default.
• W2149274570 cites W2128147740 @default.
• W2149274570 cites W2131840309 @default.
• W2149274570 cites W2134801690 @default.
• W2149274570 cites W2136267625 @default.
• W2149274570 cites W2136838504 @default.
• W2149274570 cites W2141464871 @default.
• W2149274570 cites W2145147563 @default.
• W2149274570 cites W2155984905 @default.
• W2149274570 cites W2164768118 @default.
• W2149274570 cites W2167194725 @default.
• W2149274570 cites W2184176235 @default.
• W2149274570 cites W2213727528 @default.
• W2149274570 cites W2231569610 @default.
• W2149274570 cites W2273318325 @default.
• W2149274570 cites W27330565 @default.
• W2149274570 cites W2885572916 @default.
• W2149274570 cites W4243306241 @default.
• W2149274570 cites W66242839 @default.
• W2149274570 cites W964152825 @default.
• W2149274570 doi "https://doi.org/10.1006/mcne.1998.0683" @default.
• W2149274570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9647692" @default.
• W2149274570 hasPublicationYear "1998" @default.
• W2149274570 type Work @default.
• W2149274570 sameAs 2149274570 @default.
• W2149274570 citedByCount "16" @default.
• W2149274570 countsByYear W21492745702020 @default.
• W2149274570 countsByYear W21492745702021 @default.
• W2149274570 crossrefType "journal-article" @default.
• W2149274570 hasAuthorship W2149274570A5011637469 @default.
• W2149274570 hasAuthorship W2149274570A5085819632 @default.
• W2149274570 hasConcept C104317684 @default.
• W2149274570 hasConcept C109130350 @default.
• W2149274570 hasConcept C134018914 @default.
• W2149274570 hasConcept C136397037 @default.
• W2149274570 hasConcept C169760540 @default.
• W2149274570 hasConcept C173758957 @default.
• W2149274570 hasConcept C24284526 @default.
• W2149274570 hasConcept C2777124376 @default.
• W2149274570 hasConcept C2777180181 @default.
• W2149274570 hasConcept C47002013 @default.
• W2149274570 hasConcept C53345823 @default.
• W2149274570 hasConcept C54355233 @default.
• W2149274570 hasConcept C59822182 @default.
• W2149274570 hasConcept C63932345 @default.
• W2149274570 hasConcept C71220013 @default.

• next