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- W2149281305 abstract "The purpose of this chapter is to focus on areas that are often underestimated in theirimportance for optimized results in mass spectrometric analyses, namely samplepreparation. While there is no doubt that the advancements in technology led us to wherewe are now - it is also clear that a deep understanding of appropriate sample preparationtechniques can be key to success of a proteomics experiment. Equally, lack of suchknowledge can be the source of avoidable, failed experiments. Here, we will share ourexperience and discuss common contaminants such as buffers, solubilization reagents andthose contaminants that are introduced through the use of specific biological protocols.The chapter will outline how best to deal with these common problems in order tomaximize the returns from a proteomics experiment. We will also briefly discuss theimportance of liquid chromatography and mass spectrometry optimization as well asbioinformatics tools to increase the amount of information that can be retrieved fromsuch experiments." @default.
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- W2149281305 date "2011-01-01" @default.
- W2149281305 modified "2023-09-22" @default.
- W2149281305 title "Avoiding pitfalls in proteomics sample preparation" @default.
- W2149281305 hasPublicationYear "2011" @default.
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