FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149281736> ?p ?o ?g. }

• W2149281736 endingPage "1002" @default.
• W2149281736 startingPage "997" @default.
• W2149281736 abstract "Background Positron emission tomography (PET), a new noninvasive imaging modality, utilizing 2-[F-18]-fluoro-2-deoxy-D-glucose (FDC), has demonstrated increased FDC uptake in lung tumors. Objective To determine the diagnostic efficacy of PET-FDG imaging in differentiating benign from malignant solitary pulmonary nodules. Patient selection A prospective study of 30 patients who presented with indeterminate solitary pulmonary nodules less than 3 cm in size based on chest radiograph and computed tomographic (CT) scan. Setting Two tertiary care medical centers in Omaha, Neb: Creighton University Medical Center and the Omaha Veterans Administration Medical Center. Measurements Positron emission tomographic imaging of the lung was performed 1 h after intravenous injection of 10 mCi of F-18-FDG. Qualitative analysis of the images was performed independently by two observers by visual identification of the areas of increased FDC uptake in the lung nodules. Semiquantitative analysis was performed using computation of differential uptake ratio (DUR). Histologic specimens were obtained in 29 patients (thoracotomy 20, transthoracic needle aspiration biopsy 8, bronchoscopy1). Results Positron emission tomographic imaging correctly identified 27 of 30 pulmonary nodules. Diagnostic accuracy was high with sensitivity of 95 percent and specificity of 80 percent. The positive and negative predictive value of PET imaging for solitary pulmonary nodules was 90 percent and 89 percent, respectively. The DUR values were significantly higher for malignant nodules (mean± SD, 5.55 ±2.79) than benign nodules (mean±SD, 0.95 ±0.99) (p<0.001). There was one false-negative result in a patient with a 1-cm nodule identified as a scar adenocarcinoma. There were two false-positive cases and both had caseating granulomas with active inflammation and Histoplasma organisms. Conclusion PET-FDC imaging of the lung, a new noninvasive diagnostic test, has a high degree of accuracy in differentiating benign from malignant pulmonary nodules. PET-FDC imaging could complement CT scanning in the evaluation and treatment of patients with solitary pulmonary nodules. Positron emission tomography (PET), a new noninvasive imaging modality, utilizing 2-[F-18]-fluoro-2-deoxy-D-glucose (FDC), has demonstrated increased FDC uptake in lung tumors. To determine the diagnostic efficacy of PET-FDG imaging in differentiating benign from malignant solitary pulmonary nodules. A prospective study of 30 patients who presented with indeterminate solitary pulmonary nodules less than 3 cm in size based on chest radiograph and computed tomographic (CT) scan. Two tertiary care medical centers in Omaha, Neb: Creighton University Medical Center and the Omaha Veterans Administration Medical Center. Positron emission tomographic imaging of the lung was performed 1 h after intravenous injection of 10 mCi of F-18-FDG. Qualitative analysis of the images was performed independently by two observers by visual identification of the areas of increased FDC uptake in the lung nodules. Semiquantitative analysis was performed using computation of differential uptake ratio (DUR). Histologic specimens were obtained in 29 patients (thoracotomy 20, transthoracic needle aspiration biopsy 8, bronchoscopy1). Positron emission tomographic imaging correctly identified 27 of 30 pulmonary nodules. Diagnostic accuracy was high with sensitivity of 95 percent and specificity of 80 percent. The positive and negative predictive value of PET imaging for solitary pulmonary nodules was 90 percent and 89 percent, respectively. The DUR values were significantly higher for malignant nodules (mean± SD, 5.55 ±2.79) than benign nodules (mean±SD, 0.95 ±0.99) (p<0.001). There was one false-negative result in a patient with a 1-cm nodule identified as a scar adenocarcinoma. There were two false-positive cases and both had caseating granulomas with active inflammation and Histoplasma organisms. PET-FDC imaging of the lung, a new noninvasive diagnostic test, has a high degree of accuracy in differentiating benign from malignant pulmonary nodules. PET-FDC imaging could complement CT scanning in the evaluation and treatment of patients with solitary pulmonary nodules." @default.
• W2149281736 created "2016-06-24" @default.
• W2149281736 creator A5003974303 @default.
• W2149281736 creator A5004394761 @default.
• W2149281736 creator A5043221080 @default.
• W2149281736 creator A5067032786 @default.
• W2149281736 creator A5067260566 @default.
• W2149281736 date "1993-10-01" @default.
• W2149281736 modified "2023-09-26" @default.
• W2149281736 title "Diagnostic Efficacy of PET-FDG Imaging in Solitary Pulmonary Nodules" @default.
• W2149281736 cites W1965652113 @default.
• W2149281736 cites W1978332638 @default.
• W2149281736 cites W1987947700 @default.
• W2149281736 cites W2025974957 @default.
• W2149281736 cites W2051883062 @default.
• W2149281736 cites W2052109589 @default.
• W2149281736 cites W2056851921 @default.
• W2149281736 cites W2062438495 @default.
• W2149281736 cites W2076729187 @default.
• W2149281736 cites W2078729376 @default.
• W2149281736 cites W2086028712 @default.
• W2149281736 cites W2089294097 @default.
• W2149281736 cites W2089868947 @default.
• W2149281736 cites W2091981210 @default.
• W2149281736 cites W2097912113 @default.
• W2149281736 cites W2122833820 @default.
• W2149281736 cites W2124158129 @default.
• W2149281736 cites W2174331325 @default.
• W2149281736 cites W2334574500 @default.
• W2149281736 cites W4328000885 @default.
• W2149281736 doi "https://doi.org/10.1378/chest.104.4.997" @default.
• W2149281736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8404239" @default.
• W2149281736 hasPublicationYear "1993" @default.
• W2149281736 type Work @default.
• W2149281736 sameAs 2149281736 @default.
• W2149281736 citedByCount "320" @default.
• W2149281736 countsByYear W21492817362012 @default.
• W2149281736 countsByYear W21492817362013 @default.
• W2149281736 countsByYear W21492817362014 @default.
• W2149281736 countsByYear W21492817362015 @default.
• W2149281736 countsByYear W21492817362016 @default.
• W2149281736 countsByYear W21492817362017 @default.
• W2149281736 countsByYear W21492817362018 @default.
• W2149281736 countsByYear W21492817362020 @default.
• W2149281736 countsByYear W21492817362021 @default.
• W2149281736 crossrefType "journal-article" @default.
• W2149281736 hasAuthorship W2149281736A5003974303 @default.
• W2149281736 hasAuthorship W2149281736A5004394761 @default.
• W2149281736 hasAuthorship W2149281736A5043221080 @default.
• W2149281736 hasAuthorship W2149281736A5067032786 @default.
• W2149281736 hasAuthorship W2149281736A5067260566 @default.
• W2149281736 hasConcept C126322002 @default.
• W2149281736 hasConcept C126838900 @default.
• W2149281736 hasConcept C141071460 @default.
• W2149281736 hasConcept C142724271 @default.
• W2149281736 hasConcept C151730666 @default.
• W2149281736 hasConcept C2775842073 @default.
• W2149281736 hasConcept C2775934546 @default.
• W2149281736 hasConcept C2776731575 @default.
• W2149281736 hasConcept C2777714996 @default.
• W2149281736 hasConcept C2778847313 @default.
• W2149281736 hasConcept C2780244788 @default.
• W2149281736 hasConcept C2780801072 @default.
• W2149281736 hasConcept C2781137159 @default.
• W2149281736 hasConcept C2989005 @default.
• W2149281736 hasConcept C36454342 @default.
• W2149281736 hasConcept C544519230 @default.
• W2149281736 hasConcept C71924100 @default.
• W2149281736 hasConcept C86803240 @default.
• W2149281736 hasConceptScore W2149281736C126322002 @default.
• W2149281736 hasConceptScore W2149281736C126838900 @default.
• W2149281736 hasConceptScore W2149281736C141071460 @default.
• W2149281736 hasConceptScore W2149281736C142724271 @default.
• W2149281736 hasConceptScore W2149281736C151730666 @default.
• W2149281736 hasConceptScore W2149281736C2775842073 @default.
• W2149281736 hasConceptScore W2149281736C2775934546 @default.
• W2149281736 hasConceptScore W2149281736C2776731575 @default.
• W2149281736 hasConceptScore W2149281736C2777714996 @default.
• W2149281736 hasConceptScore W2149281736C2778847313 @default.
• W2149281736 hasConceptScore W2149281736C2780244788 @default.
• W2149281736 hasConceptScore W2149281736C2780801072 @default.
• W2149281736 hasConceptScore W2149281736C2781137159 @default.
• W2149281736 hasConceptScore W2149281736C2989005 @default.
• W2149281736 hasConceptScore W2149281736C36454342 @default.
• W2149281736 hasConceptScore W2149281736C544519230 @default.
• W2149281736 hasConceptScore W2149281736C71924100 @default.
• W2149281736 hasConceptScore W2149281736C86803240 @default.
• W2149281736 hasIssue "4" @default.
• W2149281736 hasLocation W21492817361 @default.
• W2149281736 hasLocation W21492817362 @default.
• W2149281736 hasOpenAccess W2149281736 @default.
• W2149281736 hasPrimaryLocation W21492817361 @default.
• W2149281736 hasRelatedWork W1970742162 @default.
• W2149281736 hasRelatedWork W2014220756 @default.
• W2149281736 hasRelatedWork W2113154596 @default.
• W2149281736 hasRelatedWork W2158839023 @default.
• W2149281736 hasRelatedWork W2186704574 @default.
• W2149281736 hasRelatedWork W2314908462 @default.

• next