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- W2149285764 abstract "Thirteen months after starting methyldopa therapy, a 55-year-old white male patient presented with a syndrome of hemolytic anemia, arthritis, photosensitivity, and a positive antinuclear antibody test result. Methyldopa-induced antinuclear antibodies were mainly IgG, directed against class H1 histones. Antibodies to native DNA and nonhistone proteins were not detected. Upon withdrawal of methyldopa therapy, and with a short course of prednisone and danazol therapy, the patient's symptoms and hemolytic anemia resolved. His clinical symptoms and serologic abnormalities returned to normal and remained negative after 2 years of followup." @default.
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- W2149285764 date "1989-02-01" @default.
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- W2149285764 title "Methyldopa-induced systemic lupus erythematosus" @default.
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- W2149285764 doi "https://doi.org/10.1002/anr.1780320214" @default.
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