Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149287982> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2149287982 endingPage "3009" @default.
- W2149287982 startingPage "2995" @default.
- W2149287982 abstract "The three isotypes of peroxisome proliferator-activated receptors (PPARs), PPARa, β/δ and γ, are ligand-inducible transcription factors that belong to the nuclear hormone receptor family. PPARs are implicated in the control of inflammatory responses and in energy homeostasis and thus, can be defined as metabolic and anti-inflammatory transcription factors. They exert their anti-inflammatory effects by inhibiting the induction of pro-inflammatory cytokines, adhesion molecules and extracellular matrix proteins or by stimulating the production of anti-inflammatory molecules. Furthermore, PPARs modulate the proliferation, differentiation and survival of immune cells including macrophages, B cells and T cells. This review discusses the molecular mechanisms by which PPARs and their ligands modulate the inflammatory response. In addition, it presents recent developments implicating PPAR specific ligands in potential treatments of inflammationrelated diseases, such as atherosclerosis, inflammatory bowel diseases, Parkinsons and Alzheimers diseases." @default.
- W2149287982 created "2016-06-24" @default.
- W2149287982 creator A5037086101 @default.
- W2149287982 creator A5051103093 @default.
- W2149287982 creator A5078475681 @default.
- W2149287982 date "2005-12-01" @default.
- W2149287982 modified "2023-10-18" @default.
- W2149287982 title "PPARs in Diseases: Control Mechanisms of Inflammation" @default.
- W2149287982 doi "https://doi.org/10.2174/092986705774462905" @default.
- W2149287982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16378501" @default.
- W2149287982 hasPublicationYear "2005" @default.
- W2149287982 type Work @default.
- W2149287982 sameAs 2149287982 @default.
- W2149287982 citedByCount "173" @default.
- W2149287982 countsByYear W21492879822012 @default.
- W2149287982 countsByYear W21492879822013 @default.
- W2149287982 countsByYear W21492879822014 @default.
- W2149287982 countsByYear W21492879822015 @default.
- W2149287982 countsByYear W21492879822016 @default.
- W2149287982 countsByYear W21492879822017 @default.
- W2149287982 countsByYear W21492879822018 @default.
- W2149287982 countsByYear W21492879822019 @default.
- W2149287982 countsByYear W21492879822020 @default.
- W2149287982 countsByYear W21492879822021 @default.
- W2149287982 countsByYear W21492879822022 @default.
- W2149287982 countsByYear W21492879822023 @default.
- W2149287982 crossrefType "journal-article" @default.
- W2149287982 hasAuthorship W2149287982A5037086101 @default.
- W2149287982 hasAuthorship W2149287982A5051103093 @default.
- W2149287982 hasAuthorship W2149287982A5078475681 @default.
- W2149287982 hasConcept C104317684 @default.
- W2149287982 hasConcept C16224149 @default.
- W2149287982 hasConcept C170493617 @default.
- W2149287982 hasConcept C185592680 @default.
- W2149287982 hasConcept C187345961 @default.
- W2149287982 hasConcept C203014093 @default.
- W2149287982 hasConcept C2776914184 @default.
- W2149287982 hasConcept C55493867 @default.
- W2149287982 hasConcept C63645605 @default.
- W2149287982 hasConcept C63932345 @default.
- W2149287982 hasConcept C86339819 @default.
- W2149287982 hasConcept C86803240 @default.
- W2149287982 hasConcept C8891405 @default.
- W2149287982 hasConcept C95444343 @default.
- W2149287982 hasConceptScore W2149287982C104317684 @default.
- W2149287982 hasConceptScore W2149287982C16224149 @default.
- W2149287982 hasConceptScore W2149287982C170493617 @default.
- W2149287982 hasConceptScore W2149287982C185592680 @default.
- W2149287982 hasConceptScore W2149287982C187345961 @default.
- W2149287982 hasConceptScore W2149287982C203014093 @default.
- W2149287982 hasConceptScore W2149287982C2776914184 @default.
- W2149287982 hasConceptScore W2149287982C55493867 @default.
- W2149287982 hasConceptScore W2149287982C63645605 @default.
- W2149287982 hasConceptScore W2149287982C63932345 @default.
- W2149287982 hasConceptScore W2149287982C86339819 @default.
- W2149287982 hasConceptScore W2149287982C86803240 @default.
- W2149287982 hasConceptScore W2149287982C8891405 @default.
- W2149287982 hasConceptScore W2149287982C95444343 @default.
- W2149287982 hasIssue "25" @default.
- W2149287982 hasLocation W21492879821 @default.
- W2149287982 hasLocation W21492879822 @default.
- W2149287982 hasOpenAccess W2149287982 @default.
- W2149287982 hasPrimaryLocation W21492879821 @default.
- W2149287982 hasRelatedWork W2000314727 @default.
- W2149287982 hasRelatedWork W2029952579 @default.
- W2149287982 hasRelatedWork W2300083810 @default.
- W2149287982 hasRelatedWork W2316296538 @default.
- W2149287982 hasRelatedWork W2348701128 @default.
- W2149287982 hasRelatedWork W2363579653 @default.
- W2149287982 hasRelatedWork W2393668389 @default.
- W2149287982 hasRelatedWork W2409513872 @default.
- W2149287982 hasRelatedWork W2999117591 @default.
- W2149287982 hasRelatedWork W191592690 @default.
- W2149287982 hasVolume "12" @default.
- W2149287982 isParatext "false" @default.
- W2149287982 isRetracted "false" @default.
- W2149287982 magId "2149287982" @default.
- W2149287982 workType "article" @default.