FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149374964> ?p ?o ?g. }

• W2149374964 endingPage "381" @default.
• W2149374964 startingPage "369" @default.
• W2149374964 abstract "The aim of the present paper was to describe the mechanisms and management of antipsychotic-induced weight gain in schizophrenia patients. A comprehensive literature review of all available articles on the mechanisms and management of antipsychotic-induced weight gain was done by searching databases PsychINFO and PubMed. A summary of the available guidelines for monitoring of antipsychotic-induced weight gain and metabolic syndrome is also provided. There has been a substantial increase in the number of studies investigating the mechanisms and management of antipsychotic-induced weight gain after 2002. These include advances in the understanding of pharmacogenomics of weight gain and several randomized controlled trials (RCTs) evaluating pharmacological and psychological treatments to promote weight loss. The most effective strategy for prevention of weight gain is the choice of antipsychotic medication with low weight gain potential. In individuals with established weight gain and metabolic issues, switching to an antipsychotic agent with lower weight gain potential and/or lifestyle modifications with physical activity are most effective in promoting weight loss. Pharmacological agents such as orlistat and sibutramine are effective in general obesity but have not been sufficiently evaluated in antipsychotic-induced weight gain. The case to prescribe routine pharmacological treatment to promote weight loss is weak. Long-term, pragmatic studies are required to inform clinical practice. Weight gain in schizophrenia is associated with significant physical and psychological morbidity. Achieving an optimal trade-off between effectiveness and side-effects of antipsychotic agents, although difficult, is achievable. This should be based on three main principles: (i) a shared decision-making model between the patient, clinician and carer(s) when choosing an antipsychotic; (ii) a commitment to baseline and follow-up monitoring with explicit identification of the responsible individual or team; and (iii) the adoption of clear structured protocols for clinicians to follow in case of clinically significant weight gain and metabolic issues, which should incorporate greater collaboration between various health professionals from psychiatric and medical specialist services." @default.
• W2149374964 created "2016-06-24" @default.
• W2149374964 creator A5063220383 @default.
• W2149374964 date "2008-01-01" @default.
• W2149374964 modified "2023-09-27" @default.
• W2149374964 title "Antipsychotic Induced Weight Gain in Schizophrenia: Mechanisms and Management" @default.
• W2149374964 cites W1488696416 @default.
• W2149374964 cites W1512329974 @default.
• W2149374964 cites W1941383034 @default.
• W2149374964 cites W1943105996 @default.
• W2149374964 cites W1964652901 @default.
• W2149374964 cites W1965144722 @default.
• W2149374964 cites W1965780343 @default.
• W2149374964 cites W1970482380 @default.
• W2149374964 cites W1972080797 @default.
• W2149374964 cites W1974967636 @default.
• W2149374964 cites W1978158016 @default.
• W2149374964 cites W1980391156 @default.
• W2149374964 cites W1982501208 @default.
• W2149374964 cites W1983071462 @default.
• W2149374964 cites W1983759188 @default.
• W2149374964 cites W1984732060 @default.
• W2149374964 cites W1986376350 @default.
• W2149374964 cites W1988714288 @default.
• W2149374964 cites W1992197921 @default.
• W2149374964 cites W1993446055 @default.
• W2149374964 cites W1995060015 @default.
• W2149374964 cites W1995329837 @default.
• W2149374964 cites W1995523980 @default.
• W2149374964 cites W1999095420 @default.
• W2149374964 cites W2000226432 @default.
• W2149374964 cites W2002701207 @default.
• W2149374964 cites W2015076276 @default.
• W2149374964 cites W2016362292 @default.
• W2149374964 cites W2027573756 @default.
• W2149374964 cites W2027602369 @default.
• W2149374964 cites W2029663626 @default.
• W2149374964 cites W2031217954 @default.
• W2149374964 cites W2033858169 @default.
• W2149374964 cites W2036930310 @default.
• W2149374964 cites W2039605943 @default.
• W2149374964 cites W2040340453 @default.
• W2149374964 cites W2041662031 @default.
• W2149374964 cites W2042826217 @default.
• W2149374964 cites W2044364656 @default.
• W2149374964 cites W2046012884 @default.
• W2149374964 cites W2047946696 @default.
• W2149374964 cites W2049707875 @default.
• W2149374964 cites W2052350817 @default.
• W2149374964 cites W2053508950 @default.
• W2149374964 cites W2053550022 @default.
• W2149374964 cites W2054296290 @default.
• W2149374964 cites W2054299066 @default.
• W2149374964 cites W2060894123 @default.
• W2149374964 cites W2064370832 @default.
• W2149374964 cites W2066284526 @default.
• W2149374964 cites W2066964991 @default.
• W2149374964 cites W2067763161 @default.
• W2149374964 cites W2070213965 @default.
• W2149374964 cites W2074044948 @default.
• W2149374964 cites W2075480382 @default.
• W2149374964 cites W2075512479 @default.
• W2149374964 cites W2078298988 @default.
• W2149374964 cites W2078771025 @default.
• W2149374964 cites W2079567719 @default.
• W2149374964 cites W2082322888 @default.
• W2149374964 cites W2085017297 @default.
• W2149374964 cites W2085646012 @default.
• W2149374964 cites W2088688771 @default.
• W2149374964 cites W2090786172 @default.
• W2149374964 cites W2094381952 @default.
• W2149374964 cites W2101762862 @default.
• W2149374964 cites W2102880815 @default.
• W2149374964 cites W2104997591 @default.
• W2149374964 cites W2105786227 @default.
• W2149374964 cites W2108988641 @default.
• W2149374964 cites W2111105929 @default.
• W2149374964 cites W2112271959 @default.
• W2149374964 cites W2113540412 @default.
• W2149374964 cites W2113867823 @default.
• W2149374964 cites W2114801996 @default.
• W2149374964 cites W2115027765 @default.
• W2149374964 cites W2115057047 @default.
• W2149374964 cites W2115134494 @default.
• W2149374964 cites W2120588226 @default.
• W2149374964 cites W2123409433 @default.
• W2149374964 cites W2123530223 @default.
• W2149374964 cites W2130670966 @default.
• W2149374964 cites W2131650924 @default.
• W2149374964 cites W2132495209 @default.
• W2149374964 cites W2132930967 @default.
• W2149374964 cites W2137417913 @default.
• W2149374964 cites W2137568454 @default.
• W2149374964 cites W2146830005 @default.
• W2149374964 cites W2146966049 @default.
• W2149374964 cites W2149830716 @default.
• W2149374964 cites W2153744963 @default.
• W2149374964 cites W2156659475 @default.

• next