Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149376434> ?p ?o ?g. }
- W2149376434 endingPage "230" @default.
- W2149376434 startingPage "224" @default.
- W2149376434 abstract "The recent evolution of Plasmodium falciparum is at odds with the extensive polymorphism found in most genes coding for antigens. Here, we examined the patterns and putative mechanisms of sequence diversification in the merozoite surface protein-2 (MSP-2), a major malarial repetitive surface antigen. We compared the msp-2 gene sequences from closely related clones derived from sympatric parasite isolates from Brazilian Amazonia and used microsatellite typing to examine, in these same clones, the haplotype background of chromosome 2, where msp-2 is located. We found examples of msp-2 sequence rearrangements putatively created by nonreciprocal recombinational events, such as replication slippage and gene conversion, while maintaining the chromosome haplotype. We conclude that these nonreciprocal recombination events may represent a major source of antigenic diversity in MSP-2 in P. falciparum populations with low rates of classical meiotic recombination." @default.
- W2149376434 created "2016-06-24" @default.
- W2149376434 creator A5008869091 @default.
- W2149376434 creator A5029777006 @default.
- W2149376434 creator A5032097589 @default.
- W2149376434 creator A5039438183 @default.
- W2149376434 creator A5045348162 @default.
- W2149376434 creator A5057264842 @default.
- W2149376434 creator A5062896436 @default.
- W2149376434 creator A5063300591 @default.
- W2149376434 creator A5078824892 @default.
- W2149376434 date "2006-07-01" @default.
- W2149376434 modified "2023-10-01" @default.
- W2149376434 title "Origins of sequence diversity in the malaria vaccine candidate merozoite surface protein-2 (MSP-2) in Amazonian isolates of Plasmodium falciparum" @default.
- W2149376434 cites W1485825200 @default.
- W2149376434 cites W1871678940 @default.
- W2149376434 cites W1902880673 @default.
- W2149376434 cites W1968447227 @default.
- W2149376434 cites W1969503178 @default.
- W2149376434 cites W1970700657 @default.
- W2149376434 cites W1985100564 @default.
- W2149376434 cites W1996027178 @default.
- W2149376434 cites W1996674271 @default.
- W2149376434 cites W2016478791 @default.
- W2149376434 cites W2019851585 @default.
- W2149376434 cites W2026791163 @default.
- W2149376434 cites W2035054548 @default.
- W2149376434 cites W2041067932 @default.
- W2149376434 cites W2042709462 @default.
- W2149376434 cites W2048296548 @default.
- W2149376434 cites W2052159816 @default.
- W2149376434 cites W2069441054 @default.
- W2149376434 cites W2074874530 @default.
- W2149376434 cites W2086386648 @default.
- W2149376434 cites W2090725059 @default.
- W2149376434 cites W2093994250 @default.
- W2149376434 cites W2108679796 @default.
- W2149376434 cites W2119629266 @default.
- W2149376434 cites W2137134809 @default.
- W2149376434 cites W2146292805 @default.
- W2149376434 cites W2155700184 @default.
- W2149376434 cites W2159487337 @default.
- W2149376434 cites W2165672288 @default.
- W2149376434 cites W2170589905 @default.
- W2149376434 cites W2170874271 @default.
- W2149376434 cites W4231922091 @default.
- W2149376434 doi "https://doi.org/10.1016/j.gene.2006.03.011" @default.
- W2149376434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16716539" @default.
- W2149376434 hasPublicationYear "2006" @default.
- W2149376434 type Work @default.
- W2149376434 sameAs 2149376434 @default.
- W2149376434 citedByCount "17" @default.
- W2149376434 countsByYear W21493764342012 @default.
- W2149376434 countsByYear W21493764342013 @default.
- W2149376434 countsByYear W21493764342015 @default.
- W2149376434 countsByYear W21493764342017 @default.
- W2149376434 countsByYear W21493764342018 @default.
- W2149376434 countsByYear W21493764342019 @default.
- W2149376434 crossrefType "journal-article" @default.
- W2149376434 hasAuthorship W2149376434A5008869091 @default.
- W2149376434 hasAuthorship W2149376434A5029777006 @default.
- W2149376434 hasAuthorship W2149376434A5032097589 @default.
- W2149376434 hasAuthorship W2149376434A5039438183 @default.
- W2149376434 hasAuthorship W2149376434A5045348162 @default.
- W2149376434 hasAuthorship W2149376434A5057264842 @default.
- W2149376434 hasAuthorship W2149376434A5062896436 @default.
- W2149376434 hasAuthorship W2149376434A5063300591 @default.
- W2149376434 hasAuthorship W2149376434A5078824892 @default.
- W2149376434 hasConcept C104317684 @default.
- W2149376434 hasConcept C112212490 @default.
- W2149376434 hasConcept C135763542 @default.
- W2149376434 hasConcept C156695909 @default.
- W2149376434 hasConcept C159047783 @default.
- W2149376434 hasConcept C197754878 @default.
- W2149376434 hasConcept C203014093 @default.
- W2149376434 hasConcept C2778048844 @default.
- W2149376434 hasConcept C2778371730 @default.
- W2149376434 hasConcept C2781034427 @default.
- W2149376434 hasConcept C54355233 @default.
- W2149376434 hasConcept C86803240 @default.
- W2149376434 hasConceptScore W2149376434C104317684 @default.
- W2149376434 hasConceptScore W2149376434C112212490 @default.
- W2149376434 hasConceptScore W2149376434C135763542 @default.
- W2149376434 hasConceptScore W2149376434C156695909 @default.
- W2149376434 hasConceptScore W2149376434C159047783 @default.
- W2149376434 hasConceptScore W2149376434C197754878 @default.
- W2149376434 hasConceptScore W2149376434C203014093 @default.
- W2149376434 hasConceptScore W2149376434C2778048844 @default.
- W2149376434 hasConceptScore W2149376434C2778371730 @default.
- W2149376434 hasConceptScore W2149376434C2781034427 @default.
- W2149376434 hasConceptScore W2149376434C54355233 @default.
- W2149376434 hasConceptScore W2149376434C86803240 @default.
- W2149376434 hasIssue "2" @default.
- W2149376434 hasLocation W21493764341 @default.
- W2149376434 hasLocation W21493764342 @default.
- W2149376434 hasOpenAccess W2149376434 @default.
- W2149376434 hasPrimaryLocation W21493764341 @default.
- W2149376434 hasRelatedWork W1965237847 @default.