FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149405576> ?p ?o ?g. }

• W2149405576 endingPage "657" @default.
• W2149405576 startingPage "651" @default.
• W2149405576 abstract "ABSTRACT Tuberculosis (TB) in humans is caused by members of the Mycobacterium tuberculosis complex (MTC). Rapid detection of the MTC is necessary for the timely initiation of antibiotic treatment, while differentiation between members of the complex may be important to guide the appropriate antibiotic treatment and provide epidemiological information. In this study, a multiplex real-time PCR diagnostics assay using novel molecular targets was designed to identify the MTC while simultaneously differentiating between M. tuberculosis and M. canettii . The lepA gene was targeted for the detection of members of the MTC, the wbbl1 gene was used for the differentiation of M. tuberculosis and M. canettii from the remainder of the complex, and a unique region of the M. canettii genome, a possible novel region of difference (RD), was targeted for the specific identification of M. canettii . The multiplex real-time PCR assay was tested using 125 bacterial strains (64 MTC isolates, 44 nontuberculosis mycobacteria [NTM], and 17 other bacteria). The assay was determined to be 100% specific for the mycobacteria tested. Limits of detection of 2.2, 2.17, and 0.73 cell equivalents were determined for M. tuberculosis / M. canettii , the MTC, and M. canettii , respectively, using probit regression analysis. Further validation of this diagnostics assay, using clinical samples, should demonstrate its potential for the rapid, accurate, and sensitive diagnosis of TB caused by M. tuberculosis , M. canettii , and the other members of the MTC." @default.
• W2149405576 created "2016-06-24" @default.
• W2149405576 creator A5025754154 @default.
• W2149405576 creator A5035435086 @default.
• W2149405576 creator A5035894629 @default.
• W2149405576 creator A5039476787 @default.
• W2149405576 creator A5069432726 @default.
• W2149405576 creator A5072839564 @default.
• W2149405576 date "2011-02-01" @default.
• W2149405576 modified "2023-10-01" @default.
• W2149405576 title "Novel Multiplex Real-Time PCR Diagnostic Assay for Identification and Differentiation of Mycobacterium tuberculosis, Mycobacterium canettii, and Mycobacterium tuberculosis Complex Strains" @default.
• W2149405576 cites W130900827 @default.
• W2149405576 cites W1546792409 @default.
• W2149405576 cites W161088928 @default.
• W2149405576 cites W1903307467 @default.
• W2149405576 cites W1938914100 @default.
• W2149405576 cites W1977217467 @default.
• W2149405576 cites W1986974687 @default.
• W2149405576 cites W1992232200 @default.
• W2149405576 cites W1994580619 @default.
• W2149405576 cites W2018280419 @default.
• W2149405576 cites W2020110672 @default.
• W2149405576 cites W2024974612 @default.
• W2149405576 cites W2052791500 @default.
• W2149405576 cites W2079365047 @default.
• W2149405576 cites W2097920517 @default.
• W2149405576 cites W2102030014 @default.
• W2149405576 cites W2103629091 @default.
• W2149405576 cites W2103806571 @default.
• W2149405576 cites W2104145784 @default.
• W2149405576 cites W2108278673 @default.
• W2149405576 cites W2113265821 @default.
• W2149405576 cites W2127991349 @default.
• W2149405576 cites W2130559210 @default.
• W2149405576 cites W2130568458 @default.
• W2149405576 cites W2132658179 @default.
• W2149405576 cites W2133783230 @default.
• W2149405576 cites W2135717170 @default.
• W2149405576 cites W2141439851 @default.
• W2149405576 cites W2147955285 @default.
• W2149405576 cites W2148856546 @default.
• W2149405576 cites W2152388481 @default.
• W2149405576 cites W2161350984 @default.
• W2149405576 cites W2161865728 @default.
• W2149405576 cites W2163554056 @default.
• W2149405576 cites W2164931582 @default.
• W2149405576 cites W2165906391 @default.
• W2149405576 cites W2167903799 @default.
• W2149405576 cites W2169973271 @default.
• W2149405576 doi "https://doi.org/10.1128/jcm.01426-10" @default.
• W2149405576 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3043491" @default.
• W2149405576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21123525" @default.
• W2149405576 hasPublicationYear "2011" @default.
• W2149405576 type Work @default.
• W2149405576 sameAs 2149405576 @default.
• W2149405576 citedByCount "26" @default.
• W2149405576 countsByYear W21494055762012 @default.
• W2149405576 countsByYear W21494055762013 @default.
• W2149405576 countsByYear W21494055762014 @default.
• W2149405576 countsByYear W21494055762015 @default.
• W2149405576 countsByYear W21494055762016 @default.
• W2149405576 countsByYear W21494055762017 @default.
• W2149405576 countsByYear W21494055762018 @default.
• W2149405576 countsByYear W21494055762019 @default.
• W2149405576 countsByYear W21494055762022 @default.
• W2149405576 crossrefType "journal-article" @default.
• W2149405576 hasAuthorship W2149405576A5025754154 @default.
• W2149405576 hasAuthorship W2149405576A5035435086 @default.
• W2149405576 hasAuthorship W2149405576A5035894629 @default.
• W2149405576 hasAuthorship W2149405576A5039476787 @default.
• W2149405576 hasAuthorship W2149405576A5069432726 @default.
• W2149405576 hasAuthorship W2149405576A5072839564 @default.
• W2149405576 hasBestOaLocation W21494055762 @default.
• W2149405576 hasConcept C104317684 @default.
• W2149405576 hasConcept C142724271 @default.
• W2149405576 hasConcept C159047783 @default.
• W2149405576 hasConcept C2777975735 @default.
• W2149405576 hasConcept C2778679867 @default.
• W2149405576 hasConcept C2779790121 @default.
• W2149405576 hasConcept C2780374374 @default.
• W2149405576 hasConcept C2781069245 @default.
• W2149405576 hasConcept C2781188995 @default.
• W2149405576 hasConcept C49105822 @default.
• W2149405576 hasConcept C54355233 @default.
• W2149405576 hasConcept C71924100 @default.
• W2149405576 hasConcept C86803240 @default.
• W2149405576 hasConcept C89423630 @default.
• W2149405576 hasConcept C90583042 @default.
• W2149405576 hasConceptScore W2149405576C104317684 @default.
• W2149405576 hasConceptScore W2149405576C142724271 @default.
• W2149405576 hasConceptScore W2149405576C159047783 @default.
• W2149405576 hasConceptScore W2149405576C2777975735 @default.
• W2149405576 hasConceptScore W2149405576C2778679867 @default.
• W2149405576 hasConceptScore W2149405576C2779790121 @default.
• W2149405576 hasConceptScore W2149405576C2780374374 @default.
• W2149405576 hasConceptScore W2149405576C2781069245 @default.
• W2149405576 hasConceptScore W2149405576C2781188995 @default.
• W2149405576 hasConceptScore W2149405576C49105822 @default.

• next