Matches in SemOpenAlex for { <https://semopenalex.org/work/W2149437278> ?p ?o ?g. }
- W2149437278 endingPage "352" @default.
- W2149437278 startingPage "341" @default.
- W2149437278 abstract "The management of congenital adrenal hyperplasia involves suppression of adrenal androgen production, in addition to treatment of adrenal insufficiency. Management of adolescents with congenital adrenal hyperplasia is especially challenging because changes in the hormonal milieu during puberty can lead to inadequate suppression of adrenal androgens, psychosocial issues often affect adherence to medical therapy, and sexual function plays a major part in adolescence and young adulthood. For these reasons, treatment regimen reassessment is indicated during adolescence. Patients with non-classic congenital adrenal hyperplasia require reassessment regarding the need for glucocorticoid drug treatment. No clinical trials have compared various regimens for classic congenital adrenal hyperplasia in adults, thus therapy is individualised and based on the prevention of adverse outcomes. Extensive patient education is key during transition from paediatric care to adult care and should include education of females with classic congenital adrenal hyperplasia regarding their genital anatomy and surgical history. Common issues for these patients include urinary incontinence, vaginal stenosis, clitoral pain, and cosmetic concerns; for males with classic congenital adrenal hyperplasia, common issues include testicular adrenal rest tumours. Transition from paediatric to adult care is most successful when phased over many years. Education of health-care providers on how to successfully transition patients is greatly needed. The management of congenital adrenal hyperplasia involves suppression of adrenal androgen production, in addition to treatment of adrenal insufficiency. Management of adolescents with congenital adrenal hyperplasia is especially challenging because changes in the hormonal milieu during puberty can lead to inadequate suppression of adrenal androgens, psychosocial issues often affect adherence to medical therapy, and sexual function plays a major part in adolescence and young adulthood. For these reasons, treatment regimen reassessment is indicated during adolescence. Patients with non-classic congenital adrenal hyperplasia require reassessment regarding the need for glucocorticoid drug treatment. No clinical trials have compared various regimens for classic congenital adrenal hyperplasia in adults, thus therapy is individualised and based on the prevention of adverse outcomes. Extensive patient education is key during transition from paediatric care to adult care and should include education of females with classic congenital adrenal hyperplasia regarding their genital anatomy and surgical history. Common issues for these patients include urinary incontinence, vaginal stenosis, clitoral pain, and cosmetic concerns; for males with classic congenital adrenal hyperplasia, common issues include testicular adrenal rest tumours. Transition from paediatric to adult care is most successful when phased over many years. Education of health-care providers on how to successfully transition patients is greatly needed." @default.
- W2149437278 created "2016-06-24" @default.
- W2149437278 creator A5021756024 @default.
- W2149437278 creator A5090886190 @default.
- W2149437278 date "2013-12-01" @default.
- W2149437278 modified "2023-10-14" @default.
- W2149437278 title "Management of adolescents with congenital adrenal hyperplasia" @default.
- W2149437278 cites W136348730 @default.
- W2149437278 cites W1819182952 @default.
- W2149437278 cites W1963721655 @default.
- W2149437278 cites W1971566801 @default.
- W2149437278 cites W1971946657 @default.
- W2149437278 cites W1972087695 @default.
- W2149437278 cites W1977128264 @default.
- W2149437278 cites W1979323952 @default.
- W2149437278 cites W1979700466 @default.
- W2149437278 cites W1981718662 @default.
- W2149437278 cites W1988095012 @default.
- W2149437278 cites W1989173779 @default.
- W2149437278 cites W1993597474 @default.
- W2149437278 cites W1993728185 @default.
- W2149437278 cites W2000606801 @default.
- W2149437278 cites W2002092647 @default.
- W2149437278 cites W2007492491 @default.
- W2149437278 cites W2010913631 @default.
- W2149437278 cites W2020519708 @default.
- W2149437278 cites W2025433659 @default.
- W2149437278 cites W2029059844 @default.
- W2149437278 cites W2032024914 @default.
- W2149437278 cites W2035894113 @default.
- W2149437278 cites W2057322180 @default.
- W2149437278 cites W2059708085 @default.
- W2149437278 cites W2060134694 @default.
- W2149437278 cites W2065052319 @default.
- W2149437278 cites W2066490294 @default.
- W2149437278 cites W2067033063 @default.
- W2149437278 cites W2073726358 @default.
- W2149437278 cites W2073903800 @default.
- W2149437278 cites W2075804064 @default.
- W2149437278 cites W2077074712 @default.
- W2149437278 cites W2078319644 @default.
- W2149437278 cites W2079774827 @default.
- W2149437278 cites W2081542685 @default.
- W2149437278 cites W2087901274 @default.
- W2149437278 cites W2093319681 @default.
- W2149437278 cites W2094489780 @default.
- W2149437278 cites W2095652975 @default.
- W2149437278 cites W2097459572 @default.
- W2149437278 cites W2099933339 @default.
- W2149437278 cites W2100016925 @default.
- W2149437278 cites W2103699943 @default.
- W2149437278 cites W2108183811 @default.
- W2149437278 cites W2112198851 @default.
- W2149437278 cites W2113189473 @default.
- W2149437278 cites W2117425767 @default.
- W2149437278 cites W2118197855 @default.
- W2149437278 cites W2118556129 @default.
- W2149437278 cites W2119277329 @default.
- W2149437278 cites W2119916816 @default.
- W2149437278 cites W2120918030 @default.
- W2149437278 cites W2121649468 @default.
- W2149437278 cites W2123331625 @default.
- W2149437278 cites W2124353228 @default.
- W2149437278 cites W2124458165 @default.
- W2149437278 cites W2128532760 @default.
- W2149437278 cites W2129571572 @default.
- W2149437278 cites W2129778008 @default.
- W2149437278 cites W2132144622 @default.
- W2149437278 cites W2135626592 @default.
- W2149437278 cites W2135707678 @default.
- W2149437278 cites W2135973391 @default.
- W2149437278 cites W2136864398 @default.
- W2149437278 cites W2138134011 @default.
- W2149437278 cites W2138979064 @default.
- W2149437278 cites W2142217249 @default.
- W2149437278 cites W2144250683 @default.
- W2149437278 cites W2147891871 @default.
- W2149437278 cites W2148272405 @default.
- W2149437278 cites W2149660633 @default.
- W2149437278 cites W2157865750 @default.
- W2149437278 cites W2158627290 @default.
- W2149437278 cites W2160090915 @default.
- W2149437278 cites W2160882127 @default.
- W2149437278 cites W2162431841 @default.
- W2149437278 cites W2165157670 @default.
- W2149437278 cites W2165873915 @default.
- W2149437278 cites W2167051167 @default.
- W2149437278 cites W2171084347 @default.
- W2149437278 cites W2417758583 @default.
- W2149437278 cites W29799815 @default.
- W2149437278 cites W3095533299 @default.
- W2149437278 cites W4229808883 @default.
- W2149437278 cites W4232753436 @default.
- W2149437278 cites W4234360283 @default.
- W2149437278 cites W4235605211 @default.
- W2149437278 cites W4237093973 @default.
- W2149437278 cites W4241699438 @default.
- W2149437278 cites W4242038942 @default.